Cheap flights from CAE to EYW (Columbia Metropolitan to Key West Intl.)

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Cheap Flights from CAE to EYW starting at $279 One Way, $335 Round Trip

Prices starting at $335 for return flights and $279 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Dec 21 - Fri, Dec 25
CAE
Columbia
EYW
Key West
$335 Roundtrip, found 1 day ago
$335
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 21 from Columbia to Key West, returning Fri, Dec 25, priced at $335 found 1 day ago
Mon, Dec 21 - Fri, Dec 25
CAE
Columbia
EYW
Key West
$377 Roundtrip, found 1 day ago
$377
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Dec 21 from Columbia to Key West, returning Fri, Dec 25, priced at $377 found 1 day ago
Mon, Dec 21 - Fri, Dec 25
CAE
Columbia
EYW
Key West
$383 Roundtrip, found 1 day ago
$383
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 21 from Columbia to Key West, returning Fri, Dec 25, priced at $383 found 1 day ago
Mon, Dec 21 - Fri, Dec 25
CAE
Columbia
EYW
Key West
$415 Roundtrip, found 1 day ago
$415
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 21 from Columbia to Key West, returning Fri, Dec 25, priced at $415 found 1 day ago
Mon, Dec 21 - Fri, Dec 25
CAE
Columbia
EYW
Key West
$416 Roundtrip, found 1 day ago
$416
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 21 from Columbia to Key West, returning Fri, Dec 25, priced at $416 found 1 day ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
The price is $243 total per night from Sep 2 to Sep 3
$243 total
per night
Sep 2 - Sep 3
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,222 reviews)
"Beautiful resort! Well kept, great staff! Only downfall of the on resort restaurant….. service fees are STEEP!"

Reviewed on Aug 9, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
The price is $166 total per night from Aug 30 to Aug 31
$166 total
per night
Aug 30 - Aug 31
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,469 reviews)
"Everything was great, had an excellent time, & would stay here again."

Reviewed on Aug 10, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
The price is $171 total per night from Aug 20 to Aug 21
$171 total
per night
Aug 20 - Aug 21
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,078 reviews)
"Thanks"

Reviewed on Aug 9, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$203 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,497 reviews)
"Hotel was nice but not worth the nightly rate or the price for the extra daily hotel fee for the amenities. The room was clean and spacious. The beach was inaccessible due to the sargassum. The pools were dirty. There was only 1 attendant at the Pineapple bar who was overworked and in a bad mood. ..."

Reviewed on Aug 10, 2026

Southernmost Beach Resort and Guesthouses
Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$192 nightly
The price is $216 total per night from Aug 11 to Aug 12
$216 total
Aug 11 - Aug 12
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (2,417 reviews)
"It was a great place, the furniture and deco very nice and high end, the shuttle to downtown a big plus. The beach OK, but you must realize that you don't go to Key West for the beach, you go for the environment in town, the people, the shopping, the food and the most amazing sunset."

Reviewed on Aug 10, 2026

Beachside Resort & Residences
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$171 nightly
The price is $192 total per night from Sep 8 to Sep 9
$192 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,614 reviews)
"Pros: Super friendly staff, very professional and attentive, pools are saltwater and nice, poolside cabanas are nice and fun if you decide to rent one for the day, Backyard bars are responsibly priced and food is good to order on site, rooms are clean. Backyard amenities and games are great for family ..."

Reviewed on Aug 10, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$152 nightly
The price is $171 total per night from Aug 20 to Aug 21
$171 total
Aug 20 - Aug 21
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,078 reviews)
"Thanks"

Reviewed on Aug 9, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$148 nightly
The price is $166 total per night from Aug 30 to Aug 31
$166 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,470 reviews)
"Clean, location was great! Loved waking up to see the beautiful view every morning!"

Reviewed on Aug 10, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$145 nightly
The price is $163 total per night from Aug 16 to Aug 17
$163 total
Aug 16 - Aug 17
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,011 reviews)
"Beautiful property. Staff were very friendly and helpful. Parking is limited which was the only downfall. Would definitely recommend and would book again"

Reviewed on Aug 8, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$155 nightly
The price is $175 total per night from Aug 25 to Aug 26
$175 total
Aug 25 - Aug 26
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,375 reviews)
"Nice spacious room. You get many coupons for nearby bars. You even get 1 free alcoholic drink from their Bar "Tipsy Rooster" :) We also ordered a golf cart through our motel's receptionist - and it was delivered to the motel. Location is a bit far from all the action of Duval St. But about 25 min ..."

Reviewed on Aug 9, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$104 nightly
The price is $117 total per night from Aug 12 to Aug 13
$117 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,004 reviews)
"Well the room was updated however no firealarm and wires were hanging out of th wall. Next room was very loud til 2am and staff wouldnt do anything about it. Pool was under maintenance for over weeks and closed to guests even though at booking nothing was mentioned about it."

Reviewed on Aug 7, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$131 nightly
The price is $144 total per night from Aug 26 to Aug 27
$144 total
Aug 26 - Aug 27
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,075 reviews)
"Very relaxing and quiet"

Reviewed on Aug 10, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$203 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,497 reviews)
"Hotel was nice but not worth the nightly rate or the price for the extra daily hotel fee for the amenities. The room was clean and spacious. The beach was inaccessible due to the sargassum. The pools were dirty. There was only 1 attendant at the Pineapple bar who was overworked and in a bad mood. ..."

Reviewed on Aug 10, 2026

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$171 nightly
The price is $192 total per night from Sep 8 to Sep 9
$192 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,614 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"Pros: Super friendly staff, very professional and attentive, pools are saltwater and nice, poolside cabanas are nice and fun if you decide to rent one for the day, Backyard bars are responsibly priced and food is good to order on site, rooms are clean. Backyard amenities and games are great for family ..."

Reviewed on Aug 10, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$175 nightly
The price is $197 total per night from Aug 17 to Aug 18
$197 total
Aug 17 - Aug 18
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
9/10 Wonderful! (1,847 reviews)
"everything is way too expensive for what you get. parking should be free. checkin is super late. it was at 6pm. then they want to charge you 50$ for 12 o'clock check out... which they didnt after i requested it removed. breakfast is expensive. Golf kart is more expensive then renting a car."

Reviewed on Aug 10, 2026

Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CAE to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
CAE Address & GPS
Address:
125-A Summer Lake
Columbia SC, 29170
United States
IATA Code:
CAE
Longitude:
-81.119497
Latitude:
33.938804
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Columbia Metropolitan Airport to Key West Intl. Airport?
You'll have to change planes if you want to fly from Columbia Metropolitan Airport to Key West Intl. Airport. Numerous carriers operate on this route with only one stopover, including American Airlines, Delta Air Lines and KLM.
What is the shortest flight from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
Relish in an in-flight wine and settle into your seat with an interesting book or movie. With the journey from Columbia to Key West taking 4 hours and 54 minutes, you'll have enough time to kick back and enjoy the ride.
How many hours flight from CAE to EYW?
It typically takes about 5 hours to journey from CAE to Key West Intl. Airport. You'll be in the air for quite some time, so take your own entertainment, like a gripping novel or a few podcasts.
What airlines have the most flights from Columbia Metropolitan Airport to EYW?
If you're hoping to book with an airline that offers direct flights from CAE to EYW, you're out of luck. You'll need to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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