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Cheap Flights From Florence Regional Airport Starting At $128 One Way, $247 Round Trip

Prices starting at $247 for return flights and $128 for one-way flights to were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cheap Flights to Florence Regional Airport starting at $128 One Way, $247 Round Trip

One way and return prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Deals On This Weekend's Flights

Origin Destination Travel Dates Flights From*
FLO Fort Lauderdale Jun 19 - Jul 13 $367
FLO New York Jun 19 - Jun 21 $369
*Prices include taxes and fees
Florence Regional Airport
Airport Name
Florence Airport
Airport Location
Florence, United States

Airport Code

Precip: 40%

Airport Data

Name of Airport
Airport IATA Code
Lowest Flight Price $128
Available Airline Carriers American Airlines
Flights Per Day
Most Popular Airline

Fly to Florence Regional Airport

When you visit Florence in South Carolina , you'll find Florence Regional Airport (FLO) to be compact, quick and convenient. People come to the city for many reasons; it's thriving economically, with many well-known financial institutions and other large international firms choosing it as a site for regional HQ's.

It's also a regional center for medicine, with three excellent hospitals and a number of pharmaceutical companies in the area.


There's also plenty to see and do for the leisure visitor. Francis Marion University, which has over 4,000 students, puts on regular shows, while the Civic Center regularly features big-name acts.

Darlington Raceway is the place to head for high speed action, and is known as the track that's "too tough to tame". Labor Day race events are extremely popular, as is the on-site Stock Car Museum, opened around 50 years ago.

Florence is also about an hour's drive from Myrtle Beach, with its vast stretches of sand and numerous restaurants, concert halls and amusement parks.

Hotels & Flights

Accommodation in the city includes a range of hotels in the center of town and a cluster of well-known motels and business hotels on I95, to the north west of downtown.

Direct flights to Florence Airport originate in Charlotte NC. The flight takes 45 minutes and the airport is just three miles from the city center.

Flights from Florence Regional Airport - Frequently Asked Questions

Where can you fly to from FLO?

Tack on Charlotte, a popular domestic destination, and you've got a list of exhilarating places to discover on your next vacation.

Does Florence, SC Airport (FLO-Florence Regional) have a hotel?

Florence, SC Airport (FLO-Florence Regional) has no accommodations in the immediate area. But don't stress. Consider your options a little farther afield and you're sure to find a comfortable place to stay before you jet off.

If you have an early flight, there's no need to endure a sleepless night in the airport when the Hotel Florence, Tapestry Collection by Hilton is only a short cab ride away. Swap hard, plastic seats for a comfortable bed and make the most of amenities like a gift shop, business center facilities and 24-hour front desk services.

What airlines fly out of Florence Regional Airport (FLO)?

If you're hoping for a hassle-free travel experience from Florence Regional Airport, lock in your airfare with American Airlines. It's the top domestic airline with flights leaving this terminal.

If I am not able to travel due to COVID-19, can I cancel my flight from Florence, SC Airport (FLO-Florence Regional)?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans from Florence, SC Airport (FLO-Florence Regional) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights from Florence, SC Airport (FLO-Florence Regional) with flexible change policies?

In most cases you'll have the option to reschedule your flight from Florence, SC Airport (FLO-Florence Regional) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is FLO?

FLO is a code used to reference Florence Regional Airport (FLO) for ticketing purposes. This code is set by the International Air Transport Association for airports across the globe.

Are there private lounges in Florence, SC Airport (FLO-Florence Regional)?

Unfortunately, FLO currently doesn't have a private lounge. But don't worry. Use the time instead to explore the terminal's shops before your flight.

Flights Review

May 27, 2019

Flight was Great!!

Mar 13, 2018

In all i was very impressed with this trip flying on American Airline.

Feb 13, 2018

Air in the plane was too cold!! I was very uncomfortable.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.