Business Hotels in Florence, SC
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Featured Florence Business Hotels

Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
$120 nightly
The price is $134 total per night
$134 total
Apr 5 - Apr 6
Total with taxes and fees
At Home2 Suites by Hilton Florence, SC, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, tours or tickets, and luggage storage. Additional amenities include a business center, an arcade/game room, and laundry facilities.
Pool
Breakfast included

Best Western Inn
1808 W Lucas Street Florence SC
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $111 total per night
$111 total
Mar 29 - Mar 30
Total with taxes and fees
Guests of Best Western Inn enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a vending machine.
Pool
Breakfast included

Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $74 total per night
$74 total
Apr 8 - Apr 9
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center features free WiFi in public areas, meeting rooms, and a business center. If you drive, put free parking to good use. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a seasonal outdoor pool, a computer station, and laundry facilities.
Pool
Breakfast included

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $97 total per night
$97 total
Apr 26 - Apr 27
Total with taxes and fees
Guests of Quality Inn & Suites Florence Civic Center enjoy a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Fairfield Inn by Marriott Hartsville
200 S 4th St Hartsville SC
Free Cancellation
Reserve now, pay when you stay
$88 nightly
The price is $99 total per night
$99 total
Apr 3 - Apr 4
Total with taxes and fees
At Fairfield Inn by Marriott Hartsville, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and express check-in.
Pool
Breakfast included

Sleep Inn Florence North
1833 Florence Park Dr Florence SC
Free Cancellation
$68 nightly
The price is $76 total per night
$76 total
Apr 19 - Apr 20
Total with taxes and fees
Sleep Inn Florence North features a gym, free WiFi in public areas, and conference space. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $146 total per night
$146 total
Apr 12 - Apr 13
Total with taxes and fees
Guests staying at Hotel Florence, Tapestry Collection by Hilton enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Other amenities at this spa hotel include meeting rooms, conference space, and a 24-hour business center.
Spa
Parking included

Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $104 total per night
$104 total
Apr 14 - Apr 15
Total with taxes and fees
Guests of Spark by Hilton Florence North I-95, SC have access to an outdoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, concierge services, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a 24-hour business center, a meeting room, and a computer station.
Pool
Breakfast included

The Inn at the Crossroads
128 West Main Street Lake City SC
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $201 total per night
$201 total
Mar 29 - Mar 30
Total with taxes and fees
The Inn at the Crossroads features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking if you drive. The front desk is staffed 24/7 to help with concierge services, luggage storage, and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a terrace.
Breakfast included
Parking included

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
Free Cancellation
$118 nightly
The price is $132 total per night
$132 total
Mar 30 - Mar 31
Total with taxes and fees
Guests of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Best Western Executive Inn
1534 Highway 38 W Latta SC
Free Cancellation
Reserve now, pay when you stay
$106 nightly
The price is $116 total per night
$116 total
Apr 5 - Apr 6
Total with taxes and fees
Guests of Best Western Executive Inn have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a business center and a vending machine.
Pool
Breakfast included

Clarion Inn & Suites Florence - Darlington
1819 West Lucas Street Florence SC
Free Cancellation
$63 nightly
The price is $71 total per night
$71 total
Apr 27 - Apr 28
Total with taxes and fees
At Clarion Inn & Suites Florence - Darlington, guests have access to a gym, free WiFi in public areas, and conference space. If you decide to drive, there's free parking. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Suburban Studios Florence I-95
1914 W Lucas St Florence SC
Free Cancellation
Reserve now, pay when you stay
$52 nightly
The price is $58 total per night
$58 total
Apr 26 - Apr 27
Total with taxes and fees
At Suburban Studios Florence I-95, guests have access to free WiFi in public areas, coffee in a common area, and laundry facilities. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include barbecue grills and a vending machine.
Parking included
Free WiFi

Comfort Suites Florence I-95
2120 West Lucas Street Florence SC
Free Cancellation
$104 nightly
The price is $116 total per night
$116 total
Apr 19 - Apr 20
Total with taxes and fees
At Comfort Suites Florence I-95, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with an area shuttle for a fee. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Florence Express Inn
3024 TV Road Florence SC
At Florence Express Inn, guests have access to an outdoor pool, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florence hotels essential information
Accommodation | 392 hotels |
|---|---|
Lowest Price | $58 |
Highest Price | $201 |
Popular hotels | Home2 Suites by Hilton Florence, SC, Best Western Inn, Days Inn by Wyndham Florence Near Civic Center, Quality Inn & Suites Florence Civic Center, Fairfield Inn by Marriott Hartsville, Sleep Inn Florence North, Hotel Florence, Tapestry Collection by Hilton, Spark by Hilton Florence North I-95, SC, The Inn at the Crossroads, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG, Best Western Executive Inn, Clarion Inn & Suites Florence - Darlington, Suburban Studios Florence I-95, Comfort Suites Florence I-95, Florence Express Inn |
Recent Business Hotels Reviews

Hyatt Place Florence Downtown
3/5 Okay
"Everything was great except the staff at the bar. The first girl didn’t know how to use a bottle opener to open a beer. I asked the second girl to put in a grilled cheese right away so I can bring it up to my 1 year old baby. It took about an hour to get this grilled cheese and it came out with the rest of my food. I was given no bag to carry my several boxes of food. The grilled cheese fell on the ground and the bartender would not take the 7 dollars off of my bill. Horrible bar service. "
A verified traveler stayed at Hyatt Place Florence Downtown
Posted 7 hours ago
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