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Hotels in Florence

Search over 127 hotels from $47

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    Jul 25 - Jul 26
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    Check prices in Florence for tonight, Jul 25 - Jul 26
    Jul 26 - Jul 27
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    Jul 30 - Aug 1
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Top Rated Florence Hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3 mi from city center
The price is $79 per night
At Park Inn by Radisson Florence, SC, guests enjoy features like an indoor pool, a 24-hour fitness center, and free WiFi in public areas. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area, a computer station, and laundry facilities.
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.15 mi from city center
The price is $57 per night
At Days Inn by Wyndham Florence/I-95 North, guests have access to free WiFi in public areas, a seasonal outdoor pool, and free newspapers. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include laundry facilities and a TV in a common area.
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.08 mi from city center
The price is $66 per night
Howard Johnson by Wyndham Florence features free WiFi in public areas, a business center, and coffee in a common area. If you plan to drive, free parking is available. Helpful staff is there to provide front-desk service during limited hours, as well as offer insight about the area. This motel also has a computer station.
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

2.5 out of 5
900 Woody Jones Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
4.21 mi from city center
The price is $105 per night
Built in 2014, the brand new Home2 Suites by Hilton Florence, SC offers an indoor pool, a 24-hour fitness center, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with tours or tickets, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, an arcade/game room, and laundry facilities.
Country Inn & Suites by Radisson, Florence, SC

Country Inn & Suites by Radisson, Florence, SC

2.5 out of 5
1739 Mandeville Rd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.04 mi from city center
The price is $83 per night
Guests of Country Inn & Suites by Radisson, Florence, SC have access to an outdoor pool, a fitness center, and free WiFi in public areas. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with concierge services, dry cleaning/laundry, and securing valuables. Additional amenities include a meeting room, a 24-hour business center, and a computer station.
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 out of 5
2140 West Lucas Street, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.28 mi from city center
The price is $97 per night
Guests of Tru by Hilton Florence I-95 have access to an indoor pool, a fitness center, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and laundry facilities.
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an IHG Hotel

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an IHG Hotel

2.5 out of 5
2101 Florence Harllee Blvd, Florence, SC
Free Cancellation
5.99 mi from city center
The price is $114 per night
At Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an IHG Hotel, guests enjoy features like an indoor pool, a 24-hour fitness center, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a 24-hour business center, free newspapers, and laundry facilities.
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

2.5 out of 5
2123 W Lucas St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.16 mi from city center
The price is $86 per night
Guests staying at La Quinta Inn & Suites by Wyndham Florence enjoy an outdoor pool, a fitness center, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, coffee/tea in a common area, and express check-out.
Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel

Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel

2.5 out of 5
3440 W Radio Dr, Florence, SC
Free Cancellation
4.41 mi from city center
The price is $122 per night
Guests of Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel have access to an indoor pool, a 24-hour fitness center, and a spa tub. If you drive, put free parking to good use. A multilingual staff is on hand to assist with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a meeting room, and a 24-hour business center.
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
3.4 mi from city center
The price is $65 per night
Guests of Microtel Inn & Suites by Wyndham Florence enjoy access to free WiFi in public areas, a 24-hour business center, and coffee in a common area. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out, free newspapers, and a vending machine.
Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence

3 out of 5
3450 W Radio Drive, Florence, SC
Free Cancellation
Reserve now, pay when you stay
4.44 mi from city center
The price is $118 per night
Built in 2018, the brand new Homewood Suites by Hilton Florence features a 24-hour fitness center, an outdoor tennis court, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has multilingual staff ready to assist with securing valuables and luggage storage. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2 out of 5
1832 1/2 Lucas Street, I95 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
2.61 mi from city center
The price is $47 per night
Super 8 by Wyndham Florence features free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is available if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This motel also has a computer station.
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Luxury Hotels in Florence

    The Mantissa Hotel

    The Mantissa Hotel

    130 East Carolina Ave, Hartsville, SC
    The price is $125 per night from Jul 27 to Jul 27
    5/5Exceptional! (5 reviews)
    The Mantissa Hotel
    Days Inn by Wyndham Dillon

    Days Inn by Wyndham Dillon

    823 Radford Blvd, Dillon, SC
    The price is $80 per night from Jul 26 to Jul 26
    2.2/5 (12 reviews)
    Days Inn by Wyndham Dillon
    Hotel Florence, Tapestry Collection by Hilton

    Hotel Florence, Tapestry Collection by Hilton

    126 W Evans St, Florence, SC
    The price is $131 per night from Aug 1 to Aug 1
    3.6/5Good! (9 reviews)
    Hotel Florence, Tapestry Collection by Hilton

Pet Friendly Florence Hotels

    La Quinta Inn & Suites by Wyndham Florence

    La Quinta Inn & Suites by Wyndham Florence

    2123 W Lucas St, Florence, SC
    The price is $86 per night from Aug 8 to Aug 8
    3.9/5Very Good! (49 reviews)
    La Quinta Inn & Suites by Wyndham Florence
    Quality Inn And Suites Civic

    Quality Inn And Suites Civic

    150 Dunbarton Dr, Florence, SC
    The price is $90 per night from Jul 26 to Jul 26
    4.1/5Very Good! (33 reviews)
    Quality Inn And Suites Civic
    Red Roof Inn Florence - Civic Center

    Red Roof Inn Florence - Civic Center

    2690 David H McLeod Boulevard, Florence, SC
    The price is $72 per night from Jul 26 to Jul 26
    3.2/5 (29 reviews)
    Red Roof Inn Florence - Civic Center

Recent Reviews

    Tru by Hilton Florence I-95

    Tru by Hilton Florence I-95

    5/5 Excellent
    "The pool and complimentary breakfast was a really nice touch. "
    A verified traveler stayed at Tru by Hilton Florence I-95
    Posted 4 days ago
    Tru by Hilton Florence I-95
    Howard Johnson by Wyndham Florence

    Howard Johnson by Wyndham Florence

    5/5 Excellent
    "Very clean with great price and location. Friendly staff. "
    A verified traveler stayed at Howard Johnson by Wyndham Florence
    Posted 5 days ago
    Howard Johnson by Wyndham Florence
    Park Inn by Radisson Florence, SC

    Park Inn by Radisson Florence, SC

    5/5 Excellent
    "This is right off the highway but a bit off the main road so no traffic noise. Close to great door dash options. We pulled in with 7 people after an 8 hour drive after a week of camping trying to get checked in before the tropical storm hit. The power was out. The front desk allowed the kids to use the pool until the power came back on. They gave us laundry soap. Exchanged quarters for us and let us use the breakfast area for our door dash dinner. They have not been anymore accommodating. They could have said we could not check in until the power came on and we would have had 4 crying, hungry, exhausted kids standing outside. "
    A verified traveler stayed at Park Inn by Radisson Florence, SC
    Posted 2 weeks ago
    Park Inn by Radisson Florence, SC