Hotels in Pamplico
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Top Rated Pamplico Hotels

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Free Cancellation
Reserve now, pay when you stay
20.97 mi from city center
$63 nightly
The price is $71 total per night
$71 total
Dec 28 - Dec 29
Total with taxes and fees
Howard Johnson by Wyndham Florence features free WiFi in public areas, a business center, and coffee in a common area. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a computer station, a vending machine, and a garden.
Breakfast included
Parking included

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Free Cancellation
20.92 mi from city center
$85 nightly
The price is $95 total per night
$95 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Park Inn by Radisson Florence, SC features a 24-hour gym, free WiFi in public areas, and a business center. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a computer station, and an arcade/game room.
Breakfast included
Pet friendly

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
19.89 mi from city center
$98 nightly
The price is $109 total per night
$109 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Comfort Inn & Suites Florence Center Area, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Free Cancellation
Reserve now, pay when you stay
17.65 mi from city center
$100 nightly
The price is $112 total per night
$112 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Guests staying at Hyatt Place Florence Downtown enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 5.40 per night. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Free Cancellation
Reserve now, pay when you stay
20.32 mi from city center
$98 nightly
The price is $109 total per night
$109 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Hampton Inn & Suites Florence Center have access to an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
Free Cancellation
Reserve now, pay when you stay
21.08 mi from city center
$94 nightly
The price is $105 total per night
$105 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Florence enjoy a gym, free WiFi in public areas, and meeting rooms. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
20.1 mi from city center
$99 nightly
The price is $111 total per night
$111 total
Dec 30 - Dec 31
Total with taxes and fees
At Residence Inn Marriott Florence, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 5 per day. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a seasonal outdoor pool.
Pool
Breakfast included

Tru by Hilton Florence I-95
2140 West Lucas Street Florence SC
Free Cancellation
Reserve now, pay when you stay
21.21 mi from city center
$97 nightly
The price is $108 total per night
$108 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests of Tru by Hilton Florence I-95 have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and an arcade/game room.
Pool
Breakfast included

Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
20.21 mi from city center
$106 nightly
The price is $119 total per night
$119 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Home2 Suites by Hilton Florence, SC, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and tours or tickets. Additional amenities include a business center, an arcade/game room, and laundry facilities.
Pool
Breakfast included

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Free Cancellation
Reserve now, pay when you stay
19.98 mi from city center
$99 nightly
The price is $111 total per night
$111 total
Dec 28 - Dec 29
Total with taxes and fees
Guests staying at TownePlace Suites by Marriott Florence enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 5.00 per day. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Free Cancellation
Reserve now, pay when you stay
21.1 mi from city center
$113 nightly
The price is $126 total per night
$126 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
At Hampton Inn & Suites Florence-North-I-95, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Staybridge Suites Florence - Civic Center by IHG
150 Westpark Drive Florence SC
Free Cancellation
20.46 mi from city center
$135 nightly
The price is $151 total per night
$151 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG features an outdoor pool, a children's pool, and a gym. There's free parking if you drive. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, conference space, and a 24-hour business center.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
How much is a Pamplico hotel?
Check Pamplico hotel room prices by star rating

4 Star Hotels
1 properties
What's the best place for a stay in Pamplico?
What are the best hotels in Pamplico?
Here are some top hotels in Pamplico:
- Park Inn by Radisson Florence, SC is located 20.9 mi away, and this hotel has free breakfast, free WiFi, and a 24-hour fitness center.
- Comfort Inn & Suites Florence Center Area is located 19.9 mi away, and this hotel has free breakfast, free WiFi, and a 24-hour fitness center.
- Hyatt Place Florence Downtown is located 17.7 mi away, and this hotel has free breakfast, free WiFi, and a 24-hour fitness center.
Pamplico hotels essential information
Accommodation | 145 hotels |
|---|---|
Lowest Price | $71 |
Highest Price | $151 |
Popular hotels | Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Comfort Inn & Suites Florence Center Area, Hyatt Place Florence Downtown, Hampton Inn & Suites Florence Center, La Quinta Inn & Suites by Wyndham Florence, Residence Inn Marriott Florence, Tru by Hilton Florence I-95, Home2 Suites by Hilton Florence, SC, TownePlace Suites by Marriott Florence, Hampton Inn & Suites Florence-North-I-95, Staybridge Suites Florence - Civic Center by IHG |
Recent Reviews

Park Inn by Radisson Florence, SC
5/5 Excellent
"Every thing perfect as always"
A verified traveler stayed at Park Inn by Radisson Florence, SC
Posted 5 days ago
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