Lake City Vacation Homes

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Featured Vacation Homes in Lake City

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Lake City

    The Inn at the Crossroads

    The Inn at the Crossroads

    128 West Main Street Lake City SC
    $121 nightly
    The price is $136 total per night from Dec 10 to Dec 11
    $136 total
    Dec 10 - Dec 11
    Total with taxes and fees
    Quality Inn & Suites Lake City

    Quality Inn & Suites Lake City

    202 N Ron Mcnair Blvd Lake City SC
    $85 nightly
    The price is $96 total per night from Nov 30 to Dec 1
    $96 total
    Nov 30 - Dec 1
    Total with taxes and fees
    Days Inn by Wyndham Lake City

    Days Inn by Wyndham Lake City

    170 S Ron Mcnair Blvd Lake City SC
    $98 nightly
    The price is $109 total per night from Nov 11 to Nov 12
    $109 total
    Nov 11 - Nov 12
    Total with taxes and fees
    6.4/10 (268 reviews)

Lake City Vacation Homes

Book vacation homes in Lake City
Next time you take a group getaway top Lake City, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Lake City vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Lake City vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Lake City; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Lake City rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Lake City is sure to be a winner.

Lake City Vacation Homes essential information

Accommodation
17 Vacation Homes
Lowest Price
$96
Highest Price
$486
Popular accommodation
The Sunny Cottage minutes to downtown, Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence., Walking distance from one of South Carolina's top Medical centers., Charming 3-bedroom townhome with Largest Accommodations in superb Florence, Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's, Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees, Hickory Haven 3Br Elegant Downtown Hidden Gem, Pineapple House: Historic. Southern Charm. Walk Downtown., 2-bedroom/2B townhome in tranquil Florence

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