Compare Florence Guest House Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Guest Houses in Florence

$145 nightly

$158 total

Mar 22 - Mar 23

Total with taxes and fees

At this guesthouse, guests have access to features like laundry facilities. This guesthouse also has barbecue grills.

Breakfast included

Pet friendly

At this guesthouse, guests have access to free WiFi in public areas, a hot tub, and laundry facilities.

Hot Tub

Free WiFi

Guests staying at this guesthouse enjoy a hot tub, laundry facilities, and a garden.

Hot Tub

Free WiFi

At this guesthouse, guests have access to features like laundry facilities. This smoke-free guesthouse also has a garden.

Free WiFi

Air conditioning

Don't see what you're looking for?

See all available properties in Florence

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florence

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

$102 nightly

$114 total

Mar 29 - Mar 30

Total with taxes and fees

9.2/10 Wonderful! (1,232 reviews)

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

$67 nightly

$75 total

Mar 23 - Mar 24

Total with taxes and fees

8.6/10 Excellent! (2,587 reviews)

Hyatt Place Florence Downtown

100 East Evans Street Florence Florence SC

$118 nightly

$132 total

Mar 30 - Mar 31

Total with taxes and fees

9/10 Wonderful! (1,001 reviews)

Florence Guest Houses essential information

Accommodation	4 Guest Houses
Lowest Price	$75
Highest Price	$158
Popular accommodation	Burch's Carriage House , Vintage Villa Guesthouse, The Cottage, Southern Charm /Southern Hospitality!