Cheap flights from LAX to FLO (Los Angeles Intl. to Florence Regional)

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Cheap Flights from LAX to FLO starting at $528 One Way, $667 Round Trip

Prices starting at $667 for return flights and $528 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$667 Roundtrip, found 6 days ago
$667
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $667 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$690 Roundtrip, found 6 days ago
$690
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $690 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$787 Roundtrip, found 6 days ago
$787
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $787 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$796 Roundtrip, found 6 days ago
$796
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $796 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$810 Roundtrip, found 6 days ago
$810
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $810 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$899 Roundtrip, found 6 days ago
$899
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $899 found 6 days ago
Fri, Jul 10 - Sun, Jul 12
LAX
Los Angeles
FLO
Florence
$967 Roundtrip, found 6 days ago
$967
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 10 from Los Angeles to Florence, returning Sun, Jul 12, priced at $967 found 6 days ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$114 nightly
The price is $128 total per night from Jul 1 to Jul 2
$128 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,000 reviews)
"I enjoyed my stay at the Hyatt... one of the keys points for me is the location... walking distance to a couple of restaurants and shops... quiet area, clean hotel , clean room, friendly helpful staff 10/10"

Reviewed on Jun 21, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$125 nightly
The price is $140 total per night from Jul 9 to Jul 10
$140 total
Jul 9 - Jul 10
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (643 reviews)
"We were pleasantly surprised by this historic gem in the small town of Florence, SC. The best part was the in-hotel restaurant called “Victors.” The waiter was so warm and helpful in recommending food and drinks for the whole family. It enhanced our experience greatly!"

Reviewed on Jun 14, 2026

Hotel Florence, Tapestry Collection by Hilton
Cozy & Inviting

Cozy & Inviting

Florence SC
Stay at this apartment in Florence. Enjoy air conditioning. Popular attractions Drs Bruce and Lee Foundation Library and War Between the States Museum are located ...
Get rates
Cozy & Inviting
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$89 nightly
The price is $100 total per night from Jun 28 to Jun 29
$100 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,327 reviews)
"The front desk staff is not friendly"

Reviewed on Jun 24, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$68 nightly
The price is $76 total per night from Jun 28 to Jun 29
$76 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,677 reviews)
"I was disappointed with the condition of this hotel. Upon entering the room, there was a noticeable mildew smell that persisted throughout my stay. I also encountered multiple bugs in the room, which was concerning. Additionally, it was next to the train tracks with multiple trains throughout the ..."

Reviewed on Jun 24, 2026

Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$109 nightly
The price is $122 total per night from Jul 5 to Jul 6
$122 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,308 reviews)
"No pool as advertised. When asked the staff said “I don’t know”. ????I selected the hotel for the pool I could not get a printed receipt before leaving. Staff said printer was not working. I asked them to at least read me the charges. They said. I would receive a email receipt. So no pool, limited ..."

Reviewed on Jun 23, 2026

Comfort Inn & Suites Florence Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$61 nightly
The price is $68 total per night from Jun 28 to Jun 29
$68 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jun 28 to Jun 29
$68 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (345 reviews)
"For the price, it was excellent for an overnight stay on road trip. Room was clean and had newer comfortable bed/mattress and bedding. Very convenient being able to park right in front of the room. Nice new light fixture on wall between beds with USB ports for both Android and iPhone. Nice size mini ..."

Reviewed on Jun 23, 2026

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$58 nightly
The price is $65 total per night from Jul 6 to Jul 7
$65 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"Our room was very dirty!! The floors were sticky! And the walls had stuff on them in 2 different places. Worst Days Inn we have ever been to."

Reviewed on Jun 22, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$134 nightly
The price is $150 total per night from Jun 28 to Jun 29
$150 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,005 reviews)
"Our 3rd time staying at this location and it is consistently staffed by kind and friendly people."

Reviewed on Jun 24, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$85 nightly
The price is $95 total per night from Jul 5 to Jul 6
$95 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (181 reviews)
"Very nice hotel. Nice front desk clerk. Breakfast could had included eggs and bacon."

Reviewed on Jun 23, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$58 nightly
The price is $65 total per night from Jul 6 to Jul 7
$65 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"Our room was very dirty!! The floors were sticky! And the walls had stuff on them in 2 different places. Worst Days Inn we have ever been to."

Reviewed on Jun 22, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LAX to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
LAX Address & GPS
Address:
One World Way
Los Angeles CA, 90045-5803
United States
IATA Code:
LAX
Longitude:
-118.408279
Latitude:
33.943399
Time Zone:
America/Los_Angeles
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from LAX to FLO?
Take the opportunity to kick back and unwind on the flight from Los Angeles to Florence. The quickest flight time from LAX to FLO is 5 hours and 36 minutes, which gives you lots of time to indulge in a tipple or get engrossed in a book.
How many hours flight from LAX to Florence Regional Airport (FLO)?
The flight from LAX to FLO takes an average of 5 hours and 47 minutes. A couple of movies, a gripping novel and a nice snooze will make the time zip by.
What airlines have the most flights from LAX to FLO?
For now, there aren't any direct flights from LAX to FLO. However, you will be able to book a flight with at least one stop. Look on the positive side — use the time to stretch your travel-weary legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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