Cheap flights from LAX to FLO (Los Angeles Intl. to Florence Regional)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from LAX to FLO starting at One Way, $372 Round Trip

Prices starting at $372 for return flights and for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3 out of 5
100 East Evans Street Florence, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,002 reviews)
"The staff, room and location were all excellent! This is a great place to stay!"

Reviewed on Jun 13, 2025

Hyatt Place Florence Downtown
Charming 3-bedroom house with AC, WiFi in lovely Florence
Charming 3-bedroom house with AC, WiFi in lovely Florence
Florence
Stay at this vacation home in Florence. Enjoy laundry facilities and air conditioning. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
Charming 3-bedroom house with AC, WiFi in lovely Florence
Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Florence
Stay at this vacation home in Florence. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
Clean, easy stay in Florence
"Our host David is wonderful and he accommodated us over the holidays with some short notice. The property is very clean and well kept. Check in and out was easy. There are plenty of towels and the kitchen has everything you’d need for a comfortable stay. I appreciated how easy it was to communicate ..."

Reviewed on Dec 26, 2024

Charming 3-bedroom home in Florence nea downtown, McLeod and MUSC hospitals.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,216 reviews)
"Everything was excellent!!! The price was excellent too!!!!"

Reviewed on Jun 10, 2025

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,061 reviews)
"Nice place to spend the weekend while visiting family. Decent breakfast, comfy bed, clean room."

Reviewed on Jun 12, 2025

Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,220 reviews)
"Great"

Reviewed on Jun 11, 2025

Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center
Red Roof Inn Florence - Civic Center
2 out of 5
2690 David H McLeod Boulevard, Florence, SC
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,000 reviews)
"The property manager on duty when I arrived was very kind and made the check in process easy. The property was clean and convenient to shopping and dining. The only observation I can make is that the exhaust fan in the bathroom was disconnected, dirty and the cover was only partially attached."

Reviewed on Jun 4, 2025

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville
Budget Inn Timmonsville
2 out of 5
2200 Cale Yarborough Highway, Timmonsville, SC
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (305 reviews)
"Very clean, updated. Easy check in and out. I will stay there again."

Reviewed on Jun 4, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center
Days Inn by Wyndham Florence Near Civic Center
2.5 out of 5
140 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,002 reviews)
"Very nice."

Reviewed on Jun 13, 2025

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SC
3 out of 5
900 Woody Jones Blvd, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
"Great customer service, clean room, affordable rates."

Reviewed on Jun 14, 2025

Home2 Suites by Hilton Florence, SC
Baymont Inn & Suites Florence by Wyndham
Baymont Inn & Suites Florence by Wyndham
2.5 out of 5
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
"Still in Renovation mode"

Reviewed on Sep 3, 2024

Baymont Inn & Suites Florence by Wyndham
Country Inn & Suites by Radisson, Florence, SC
Country Inn & Suites by Radisson, Florence, SC
2.5 out of 5
1739 Mandeville Rd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,000 reviews)
"A nice overnight stay."

Reviewed on Jun 1, 2025

Country Inn & Suites by Radisson, Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LAX to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
LAX Address & GPS
Address:
One World Way
Los Angeles CA, 90045-5803
United States
IATA Code:
LAX
Longitude:
-118.408279
Latitude:
33.943399
Time Zone:
America/Los_Angeles
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from LAX to FLO?
Take the opportunity to kick back and unwind on the flight from Los Angeles to Florence. The quickest flight time from LAX to FLO is 5 hours and 36 minutes, which gives you lots of time to indulge in a tipple or get engrossed in a book.
How many hours flight from LAX to Florence Regional Airport (FLO)?
The flight from LAX to FLO takes an average of 5 hours and 47 minutes. A couple of movies, a gripping novel and a nice snooze will make the time zip by.
What airlines have the most flights from LAX to FLO?
For now, there aren’t any direct flights from LAX to FLO. However, you will be able to book a flight with at least one stop. Look on the positive side — use the time to stretch your travel-weary legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.