Cheap flights from EWR to FLO (Newark Liberty Intl. Airport to Florence Regional)

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Cheap Flights from EWR to FLO starting at $171 One Way, $386 Round Trip

Prices starting at $386 for return flights and $171 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 14 - Sat, Feb 21
EWR
New York
FLO
Florence
$386 Roundtrip, found 4 days ago
$386
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Feb 14 from New York to Florence, returning Sat, Feb 21, priced at $386 found 4 days ago
Fri, Feb 20 - Sun, Feb 22
EWR
New York
FLO
Florence
$445 Roundtrip, found 2 days ago
$445
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Feb 20 from New York to Florence, returning Sun, Feb 22, priced at $445 found 2 days ago
Sat, Feb 14 - Sat, Feb 21
EWR
New York
FLO
Florence
$453 Roundtrip, found 4 days ago
$453
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Feb 14 from New York to Florence, returning Sat, Feb 21, priced at $453 found 4 days ago
Fri, Feb 20 - Sun, Feb 22
EWR
New York
FLO
Florence
$457 Roundtrip, found 2 days ago
$457
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Feb 20 from New York to Florence, returning Sun, Feb 22, priced at $457 found 2 days ago
Sat, Feb 14 - Sat, Feb 21
EWR
New York
FLO
Florence
$457 Roundtrip, found 4 days ago
$457
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Feb 14 from New York to Florence, returning Sat, Feb 21, priced at $457 found 4 days ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Feb 23 to Feb 24
$112 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,000 reviews)
Friendly staff

Reviewed on Feb 4, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (618 reviews)
Very nice hotel

Reviewed on Feb 1, 2026

Hotel Florence, Tapestry Collection by Hilton
Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.

Florence SC
$174 nightly
The price is $194 total per night from Feb 16 to Feb 17
$194 total
Feb 16 - Feb 17
Total with taxes and fees
Stay at this vacation home in Florence. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Old Greenwood Athletic Park and Drs Bruce and ...
9.8/10 Exceptional! (42 reviews)
Everything was great!

Reviewed on Nov 10, 2025

Walking distance from one of South Carolina's top Medical centers.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night from Feb 15 to Feb 16
$95 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,236 reviews)
Very clean. The staff was so friendly and helpful. The breakfast was great!!! I’ll definitely be back

Reviewed on Feb 12, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$96 nightly
The price is $107 total per night from Feb 15 to Feb 16
$107 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,220 reviews)
room was very clean, staff was very pleasant and easy to work with. I would recommend this place for sure, and look forward to staying there again

Reviewed on Feb 4, 2026

Comfort Inn & Suites Florence Center Area
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$67 nightly
The price is $75 total per night from Feb 15 to Feb 16
$75 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,564 reviews)
Room was great and clean, staff friendly and helpful.

Reviewed on Feb 11, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Feb 16 to Feb 17
$63 total
Feb 16 - Feb 17
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,003 reviews)
Clean quiet and safe.

Reviewed on Feb 7, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Feb 15 to Feb 16
$68 total
Feb 15 - Feb 16
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (325 reviews)
Clean room, great for price, stayed with spouse, 2 children and two pets. You can hear cars pulling in and out of this location. There was a homeless guy asking for money but you can encounter that anywhere. No bugs, no concerns. :)

Reviewed on Dec 29, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Feb 16 to Feb 17
$74 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,000 reviews)
Love this room dearly

Reviewed on Jan 30, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $118 total per night from Feb 22 to Feb 23
$118 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,006 reviews)
Everything was excellent!!

Reviewed on Feb 5, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$80 nightly
The price is $89 total per night from Feb 24 to Feb 25
$89 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (46 reviews)
Wonderful staff and very clean room and facilities ,

Reviewed on Jan 24, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Feb 16 to Feb 17
$74 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,000 reviews)
Love this room dearly

Reviewed on Jan 30, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

EWR to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
EWR Address & GPS
Address:
Building 1, Conrad Road
Newark NJ, 07114
United States
IATA Code:
EWR
Longitude:
-74.178753
Latitude:
40.689071
Time Zone:
America/New_York
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from Newark Airport to Florence Regional Airport?
Make the most of the opportunity to sit back and chill out on the flight from Newark to Florence. The shortest flight time from Liberty Intl. Airport (EWR) to Florence Regional Airport (FLO) is 3 hours, which gives you ample time to enjoy a red wine or get carried away with a good book.
How many hours flight from EWR to Florence Regional Airport?
It typically takes about 3 hours and 11 minutes to travel from Newark Airport to Florence Regional Airport. You'll be in the sky for some time, so take some entertainment, like a gripping novel or a podcast.
What airlines have the most flights from Newark Airport to Florence Regional Airport (FLO)?
Do some people-watching, have a coffee, get the blood flowing again ... Airport stopovers don't have to irritating! If you're planning to travel from Liberty Intl. Airport (EWR) to FLO, there are no direct flights. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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