Cheap flights from EWR to FLO (Newark Liberty Intl. Airport to Florence Regional)

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Cheap Flights from EWR to FLO starting at $400 One Way, $477 Round Trip

Prices starting at $477 for return flights and $400 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 15 - Mon, Oct 19
EWR
New York
FLO
Florence
$477 Roundtrip, found 2 days ago
$477
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 15 from New York to Florence, returning Mon, Oct 19, priced at $477 found 2 days ago
Wed, Sep 16 - Wed, Sep 30
EWR
New York
FLO
Florence
$477 Roundtrip, found 4 days ago
$477
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Sep 16 from New York to Florence, returning Wed, Sep 30, priced at $477 found 4 days ago
Thu, Oct 15 - Mon, Oct 19
EWR
New York
FLO
Florence
$557 Roundtrip, found 2 days ago
$557
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 15 from New York to Florence, returning Mon, Oct 19, priced at $557 found 2 days ago
Wed, Sep 16 - Wed, Sep 30
EWR
New York
FLO
Florence
$558 Roundtrip, found 4 days ago
$558
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Sep 16 from New York to Florence, returning Wed, Sep 30, priced at $558 found 4 days ago
Thu, Oct 15 - Mon, Oct 19
EWR
New York
FLO
Florence
$589 Roundtrip, found 2 days ago
$589
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 15 from New York to Florence, returning Mon, Oct 19, priced at $589 found 2 days ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Oct 5 to Oct 6
$112 total
Oct 5 - Oct 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$139 nightly
The price is $155 total per night from Sep 20 to Sep 21
$155 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (653 reviews)
"The hotel was beautiful. It was quaint and it had two different bars. One was a guitar bar where you could have appetizers and drink and the other was a four-star restaurant that was absolutely awesome. We ate there each night and had a totally different meal each night. The bartenders were friendly ..."

Reviewed on Aug 31, 2026

Hotel Florence, Tapestry Collection by Hilton
The Urban Flats

The Urban Flats

4 out of 5
135 N Dargan St Florence SC
$406 nightly
The price is $454 total per night from Sep 16 to Sep 17
$454 total
Sep 16 - Sep 17
Total with taxes and fees
Book a stay at this business-friendly aparthotel in Florence. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Florence County Museum ...
The Urban Flats
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
$88 nightly
The price is $99 total per night from Sep 10 to Sep 11
$99 total
Sep 10 - Sep 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (364 reviews)
"Our room smelled like dog poop and we didn't have all amenities we needed for our room like clean sheets, enough full-size towels, and pillows. Overall though, staff was nice."

Reviewed on Sep 8, 2026

Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,430 reviews)
"Clean, comfortable mattress, silky sheets. indoor pool did not have a heater water temperature was too cold. Continental breakfast just Ok…could be better. Location good, right off I95."

Reviewed on Sep 7, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$65 nightly
The price is $72 total per night from Sep 9 to Sep 10
$72 total
Sep 9 - Sep 10
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Oct 4 to Oct 5
$63 total
Oct 4 - Oct 5
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,002 reviews)
"Ok for night a night. Overall pretty gross."

Reviewed on Sep 6, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Sep 9 to Sep 10
$68 total
Sep 9 - Sep 10
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$65 nightly
The price is $73 total per night from Sep 20 to Sep 21
$73 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Sep 27 to Sep 28
$119 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$85 nightly
The price is $95 total per night from Oct 4 to Oct 5
$95 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (288 reviews)
"Nice, Clean and convenient location. Air conditioning was a little noisy. But overall a good place."

Reviewed on Sep 7, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$65 nightly
The price is $73 total per night from Sep 20 to Sep 21
$73 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

EWR to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
EWR Address & GPS
Address:
Building 1, Conrad Road
Newark NJ, 07114
United States
IATA Code:
EWR
Longitude:
-74.178753
Latitude:
40.689071
Time Zone:
America/New_York
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from Newark Airport to Florence Regional Airport?
Make the most of the opportunity to sit back and chill out on the flight from Newark to Florence. The shortest flight time from Liberty Intl. Airport (EWR) to Florence Regional Airport (FLO) is 3 hours, which gives you ample time to enjoy a red wine or get carried away with a good book.
How many hours flight from EWR to Florence Regional Airport?
It typically takes about 3 hours and 11 minutes to travel from Newark Airport to Florence Regional Airport. You'll be in the sky for some time, so take some entertainment, like a gripping novel or a podcast.
What airlines have the most flights from Newark Airport to Florence Regional Airport (FLO)?
Do some people-watching, have a coffee, get the blood flowing again ... Airport stopovers don't have to irritating! If you're planning to travel from Liberty Intl. Airport (EWR) to FLO, there are no direct flights. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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