Florence Vacation Homes

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Featured Vacation Homes in Florence

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florence

    Park Inn by Radisson Florence, SC

    Park Inn by Radisson Florence, SC

    1729 Mandeville Road, Florence, SC, 29501
    The price is $84 per night from Dec 4 to Dec 5
    $84
    per night
    Dec 4 - Dec 5
    4.2/5 Very Good! (907 reviews)
    Hyatt Place Florence Downtown

    Hyatt Place Florence Downtown

    100 East Evans Street Florence, Florence, SC, 29506
    The price is $116 per night from Dec 25 to Dec 26
    $116
    per night
    Dec 25 - Dec 26
    4.3/5 Excellent! (482 reviews)
    Quality Inn And Suites Civic

    Quality Inn And Suites Civic

    150 Dunbarton Dr, Florence, SC, 29501-1991
    The price is $90 per night from Dec 4 to Dec 5
    $90
    per night
    Dec 4 - Dec 5
    3.8/5 Good! (905 reviews)

Florence Vacation Homes

Book vacation homes in Florence
Next time you take a group getaway top Florence, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Florence vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Florence vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Florence; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Florence rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Florence is sure to be a winner.