Spa Resorts in Northeast Missouri, MO
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Featured Northeast Missouri Spa Resorts & Hotels

The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Free Cancellation
Reserve now, pay when you stay
$176 nightly
The price is $208 total per night
$208 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
Guests of The Royal Sonesta Chase Park Plaza St. Louis enjoy a gym, free WiFi in public areas, and meeting rooms. Valet parking is available for USD 50 per night. The 24-hour front desk has multilingual staff ready to assist with luggage storage, concierge services, and dry cleaning/laundry. Other amenities at this luxury hotel include a conference center, a business center, and a seasonal outdoor pool.
Pool
Pet friendly

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
$193 nightly
The price is $226 total per night
$226 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Ameristar Casino Resort and Spa have access to a full-service spa, a casino, and a 24-hour gym. The 24-hour front desk has multilingual staff ready to assist with luggage storage and concierge services. Other amenities at this luxury hotel include 2 hot tubs, a conference center, and a seasonal outdoor pool.

Stoney Creek Inn Quincy
3809 Broadway St Quincy IL
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $148 total per night
$148 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Stoney Creek Inn Quincy features an indoor pool, an outdoor pool, and a gym. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a sauna, free WiFi in public areas, and a hot tub.

DoubleTree by Hilton Hotel St. Louis - Chesterfield
16625 Swingley Ridge Rd Chesterfield MO
Free Cancellation
Reserve now, pay when you stay
$122 nightly
The price is $142 total per night
$142 total
Jan 23 - Jan 24, 2026
Total with taxes and fees
At DoubleTree by Hilton Hotel St. Louis - Chesterfield, guests enjoy features like an indoor pool, a gym, and indoor tennis courts. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, concierge services, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and a conference center.
Pool
Hot Tub

The Wildwood Hotel
2801 Fountain Pl Wildwood MO
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $111 total per night
$111 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at The Wildwood Hotel enjoy an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

Home2 Suites by Hilton St. Charles St.Louis
32 Research Park Circle St. Charles MO
Home2 Suites by Hilton St. Charles St.Louis features an indoor pool, a children's pool, and a 24-hour gym. There's free parking and a free area shuttle. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and concierge services. Additional amenities include free WiFi in public areas, a hot tub, and a conference center.

Hilton St. Louis at the Ballpark
1 S Broadway St. Louis MO
$130 nightly
The price is $155 total per night
$155 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
Guests of Hilton St. Louis at the Ballpark have access to an indoor pool, a gym, and a rooftop terrace. Valet parking is offered for USD 50.00 per night. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and tours or tickets. Additional amenities include free WiFi in public areas, a conference center, and a business center.
Pool
Pet friendly

Homewood Suites by Hilton St Louis - Galleria
8040 Clayton Road Richmond Heights MO
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $122 total per night
$122 total
Jan 23 - Jan 24, 2026
Total with taxes and fees
At Homewood Suites by Hilton St Louis - Galleria, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 10 per night. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
Free Cancellation
Reserve now, pay when you stay
$499 nightly
The price is $583 total per night
$583 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
The Ritz-Carlton, St. Louis features a gym, free WiFi in public areas, and meeting rooms. Valet parking is available for USD 45 per night. The front desk has multilingual staff on hand 24/7 to help with luggage storage, dry cleaning/laundry, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include conference space, a 24-hour business center, and express check-in.
Spa
Pet friendly

Drury Inn & Suites Southwest St. Louis
5 Lambert Drury Place (I-44 & 141) Valley Park MO
Free Cancellation
Reserve now, pay when you stay
$115 nightly
The price is $135 total per night
$135 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Drury Inn & Suites Southwest St. Louis features an indoor pool, an outdoor pool, and a gym. Free parking is available if you drive. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, a hot tub, and conference space.

The Westin St. Louis
811 Spruce St St. Louis MO
$144 nightly
The price is $168 total per night
$168 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Guest of The Westin St. Louis enjoy features like meeting rooms, conference space, and a business center. Valet parking is available for USD 50 per day. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, luggage storage, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include a computer station, express check-in, and express check-out.

Pear Tree Inn St. Louis Convention Center
711 N Broadway St. Louis MO
$94 nightly
The price is $110 total per night
$110 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Pear Tree Inn St. Louis Convention Center, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 19 per day. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.

Hilton Garden Inn St. Louis Airport
4450 Evans Place St. Louis MO
Free Cancellation
Reserve now, pay when you stay
$114 nightly
The price is $133 total per night
$133 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
At Hilton Garden Inn St. Louis Airport, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include conference space, express check-in, and free newspapers.

Holiday Inn St Louis SW - Route 66 by IHG
10709 Watson Rd St. Louis MO
Free Cancellation
$111 nightly
The price is $130 total per night
$130 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Holiday Inn St Louis SW - Route 66 by IHG offers a 24-hour gym, a conference center, and a 24-hour business center. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and concierge services. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a microwave in a common area.

Quality Inn & Suites Quincy - Downtown
225 South 4th Street Quincy IL
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $111 total per night
$111 total
Jan 29 - Jan 30, 2026
Total with taxes and fees
Guests of Quality Inn & Suites Quincy - Downtown enjoy a gym, free WiFi in public areas, and conference space. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, coffee/tea in a common area, and an ATM.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Northeast Missouri hotels essential information
Accommodation | 2,791 hotels |
|---|---|
Lowest Price | $110 |
Highest Price | $583 |
Popular hotels | The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, Stoney Creek Inn Quincy, DoubleTree by Hilton Hotel St. Louis - Chesterfield, The Wildwood Hotel, Home2 Suites by Hilton St. Charles St.Louis, Hilton St. Louis at the Ballpark, Homewood Suites by Hilton St Louis - Galleria, The Ritz-Carlton, St. Louis, Drury Inn & Suites Southwest St. Louis, The Westin St. Louis, Pear Tree Inn St. Louis Convention Center, Hilton Garden Inn St. Louis Airport, Holiday Inn St Louis SW - Route 66 by IHG, Quality Inn & Suites Quincy - Downtown |
Recent Spa Resorts & Hotels Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
5/5 Excellent
"Great accommodations and I loved the pet friendly environment! Looking forward to trying more of the in-room dining options next time. "
A verified traveler stayed at Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Posted 1 day ago
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