
Northeast Missouri Vacation Packages
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Price found within the past 48 hours. Click for updated prices.

2.0-star property
The West End
Central West End
8.4/10 Very Good! (389 reviews)
Feb 20 - Feb 23
3 night stay
Boston (BOS) to St. Louis (STL)
United • Non-stop roundtrip • Coach
Price was $628, price is now $546 per person
$546
per person
found 18 hours ago
First time guest. It met my needs.
Reviewed on Feb 17, 2025

4.0-star property
The Cheshire
8.6/10 Excellent! (1,002 reviews)
Feb 20 - Feb 23
3 night stay
Boston (BOS) to St. Louis (STL)
United • Non-stop roundtrip • Coach
Price was $757, price is now $636 per person
$636
per person
found 18 hours ago
We always stay here when in St. Louis. Love the place. Nice atmosphere, great pub.
Reviewed on Sep 2, 2025

4.0-star property
St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
8.4/10 Very Good! (1,001 reviews)
Mar 6 - Mar 8
2 night stay
Boston (BOS) to St. Louis (STL)
Southwest Airlines • Roundtrip • Coach
Price was $1,305, price is now $1,126 per person
$1,126
per person
found 15 hours ago
Disappointed that the main Bar and the light show were closed to guests. It was the main reason we returned to stay here again. It was closed due to a wedding reception, so I guess I understand, and congrats to the wedding couple. We just wish we knew that it was closed ahead of time.
Reviewed on Aug 11, 2025

4.0-star property
Hotel Saint Louis, Autograph Collection
Downtown St. Louis
8.8/10 Excellent! (458 reviews)
Feb 20 - Feb 23
3 night stay
Boston (BOS) to St. Louis (STL)
United • Non-stop roundtrip • Coach
Price was $757, price is now $655 per person
$655
per person
found 18 hours ago
The receptionist at the front desk was very kind and helpful. I loved how clean my room was.
Reviewed on Aug 17, 2021

4.5-star property
Ameristar Casino Resort and Spa
8.4/10 Very Good! (1,006 reviews)
Mar 6 - Mar 8
2 night stay
Boston (BOS) to St. Louis (STL)
Southwest Airlines • Roundtrip • Coach
Price was $791, price is now $688 per person
$688
per person
found 15 hours ago
Room was nice. Enjoyed the pool view and spaciousness. Staff was friendly upon arrival and departure.
Reviewed on Dec 2, 2025
Top rated hotels for your Northeast Missouri vacation package

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
90.15 mi from city center
$97 nightly
The price is $115 total per night
$115 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel features a 24-hour gym, free WiFi in public areas, and meeting rooms. Valet parking is available for USD 55 per night. The front desk has multilingual staff on hand 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a conference center, coffee/tea in a common area, and a microwave in a common area.

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
83.01 mi from city center
$94 nightly
The price is $110 total per night
$110 total
Jan 30 - Jan 31, 2026
Total with taxes and fees
Guests of Clayton Plaza Hotel & Extended Stay have access to an indoor pool, a 24-hour gym, and a sauna. Self parking is offered for USD 6.00 per night. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
89.62 mi from city center
$148 nightly
The price is $173 total per night
$173 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Guests of 21C Museum Hotel St Louis have access to an indoor pool, a gym, and a steam room. Valet parking is offered for USD 50 per day. The front desk is staffed 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Other amenities at this luxury hotel include free WiFi in public areas, meeting rooms, and a business center.
Pool
Spa
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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