Cheap flights from RDU to STL (Raleigh - Durham Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from RDU to STL starting at $64 One Way, $128 Round Trip

Prices starting at $128 for return flights and $64 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 21 - Sat, Feb 28
RDU
Raleigh
STL
St. Louis
$128 Roundtrip, found 6 days ago
$128
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Feb 21 from Raleigh to St. Louis, returning Sat, Feb 28, priced at $128 found 6 days ago
Tue, Feb 10 - Wed, Feb 18
RDU
Raleigh
STL
St. Louis
$138 Roundtrip, found 3 days ago
$138
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Feb 10 from Raleigh to St. Louis, returning Wed, Feb 18, priced at $138 found 3 days ago
Wed, Jan 21 - Sat, Jan 31
RDU
Raleigh
STL
St. Louis
$141 Roundtrip, found 4 days ago
$141
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Jan 21 from Raleigh to St. Louis, returning Sat, Jan 31, priced at $141 found 4 days ago
Sat, Feb 21 - Sat, Feb 28
RDU
Raleigh
STL
St. Louis
$145 Roundtrip, found 6 days ago
$145
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Feb 21 from Raleigh to St. Louis, returning Sat, Feb 28, priced at $145 found 6 days ago
Sat, Feb 14 - Tue, Feb 24
RDU
Raleigh
STL
St. Louis
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Feb 14 from Raleigh to St. Louis, returning Tue, Feb 24, priced at $325 found 1 day ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Jan 2 to Jan 3
$106 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,755 reviews)
Clean room, very friendly daytime desk agent-Janet. I liked that they had a water bottle refill station. They also had a bench by the outdoor smoking area, which was thoughtful, considering that smokers are a dying breed, but are often good customers.

Reviewed on Dec 26, 2025

Pear Tree Inn St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
$122 nightly
The price is $143 total per night from Jan 16 to Jan 17
$143 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,062 reviews)
Clean rooms and friendly, accommodating staff.

Reviewed on Dec 24, 2025

Renaissance St. Louis Airport Hotel
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
$108 nightly
The price is $127 total per night from Dec 29 to Dec 30
$127 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,504 reviews)
Good transport to and from car rental, a plus

Reviewed on Dec 23, 2025

Wingate by Wyndham St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$99 nightly
The price is $117 total per night from Dec 30 to Dec 31
$117 total
Dec 30 - Dec 31
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (4,025 reviews)
The parking would have been great if it was free or had an option for free parking but overall the stay was great, business friendly and nice restaurants located within the hotel.

Reviewed on Dec 26, 2025

Hyatt Regency St. Louis at The Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
$98 nightly
The price is $114 total per night from Jan 3 to Jan 4
$114 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,191 reviews)
Nice friendly staff. Clean, well stocked room. Fresh breakfast, nice variety of food.

Reviewed on Dec 27, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$97 nightly
The price is $115 total per night from Jan 25 to Jan 26
$115 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,169 reviews)
Hotel decorated beautifully for Christmas. Room was clean and well appointed. The staff were very friendly and welcoming. The ooey gooey butter cookie offered at bedtime was delicious! Will definitely stay here again!

Reviewed on Dec 24, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$53 nightly
The price is $62 total per night from Jan 11 to Jan 12
$62 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,000 reviews)
The clerk was a foreigner. I believe she was Indian which meant there was a minor language barrier.

Reviewed on Dec 21, 2025

Quality Inn St. Louis Airport Hotel
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$128 nightly
The price is $152 total per night from Jan 3 to Jan 4
$152 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
7.8/10 Good! (1,001 reviews)
….

Reviewed on Dec 19, 2025

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$115 nightly
The price is $137 total per night from Jan 3 to Jan 4
$137 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.4/10 Good! (1,003 reviews)
I like the remodel of the lobby and lounge areas. The room was as expected. Check in was fairly easy at the desk and staff was polite.

Reviewed on Dec 18, 2025

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$53 nightly
The price is $62 total per night from Jan 11 to Jan 12
$62 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,000 reviews)
The clerk was a foreigner. I believe she was Indian which meant there was a minor language barrier.

Reviewed on Dec 21, 2025

Quality Inn St. Louis Airport Hotel
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$79 nightly
The price is $92 total per night from Dec 29 to Dec 30
$92 total
Dec 29 - Dec 30
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and St. Louis Union Station are located ...
5.6/10 (821 reviews)
We needed a place near the convention center that wasn't crazy expensive. The worker and manager were both very friendly.

Reviewed on Dec 9, 2025

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...
6.6/10 (1,000 reviews)

Families like: Indoor pool, playground, game room, cribs

Travelers say...
The Pool, and things for the kids to do was great.

Reviewed on Feb 18, 2021

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$144 nightly
The price is $168 total per night from Jan 2 to Jan 3
$168 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,279 reviews)
This hotel was a pleasant surprise. The Gateway Arch National Park is within walking distance as in right next door. The staff is very friendly and helpful. Dinner was included (not sure if that’s a regular thing or just for the night we stayed). Hot tub was slightly on the cooler side for my liking ...

Reviewed on Dec 27, 2025

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$94 nightly
The price is $110 total per night from Jan 2 to Jan 3
$110 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,763 reviews)
Yes, very friendly staff, clean room

Reviewed on Dec 23, 2025

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

RDU to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
RDU Address & GPS
Address:
Raleigh/Durham NC, 27623
United States
IATA Code:
RDU
Longitude:
-78.790862
Latitude:
35.873592
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from RDU to STL?
The awesome news is Southwest Airlines flies straight from Raleigh to St. Louis, so you won't have to worry about disembarking the plane until you reach Lambert-St. Louis Intl. Airport (STL).
What is the shortest flight from Raleigh - Durham Intl. Airport (RDU) to St. Louis Lambert International Airport?
From Raleigh, the exciting sights and sounds of St. Louis are around 5 hours and 37 minutes away. Be sure to book your favorite seat, or perhaps even one with more legroom, and fly to your destination in total comfort.
How many hours flight from Raleigh–Durham Airport to Lambert-St. Louis Intl. Airport (STL)?
It typically takes about 5 hours and 43 minutes to jet from Raleigh–Durham Airport to STL. You'll be on board for quite some time, so think about bringing your own entertainment, like a newspaper or a podcast.
What airlines have the most flights from Raleigh–Durham Airport to St. Louis Lambert International Airport?
Are you ready to hit the "book" button on your Raleigh to St. Louis airfare? Make Southwest Airlines your first pick. With 52 flights per month to choose from on this route, they've got the ticket to your next unforgettable adventure.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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