Cheap flights from MDT to SAT (Harrisburg Intl. to San Antonio Intl.)

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Cheap Flights from MDT to SAT starting at $334 One Way, $329 Round Trip

Prices starting at $329 for return flights and $334 for one-way flights to San Antonio Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Sep 25 - Mon, Sep 28
MDT
Harrisburg
SAT
San Antonio
$329 Roundtrip, found 5 days ago
$329
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 25 from Harrisburg to San Antonio, returning Mon, Sep 28, priced at $329 found 5 days ago
Fri, Sep 25 - Mon, Sep 28
MDT
Harrisburg
SAT
San Antonio
$380 Roundtrip, found 5 days ago
$380
Roundtrip
found 5 days ago
Select United flight, departing Fri, Sep 25 from Harrisburg to San Antonio, returning Mon, Sep 28, priced at $380 found 5 days ago
Fri, Sep 25 - Mon, Sep 28
MDT
Harrisburg
SAT
San Antonio
$393 Roundtrip, found 5 days ago
$393
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 25 from Harrisburg to San Antonio, returning Mon, Sep 28, priced at $393 found 5 days ago
Fri, Sep 25 - Mon, Sep 28
MDT
Harrisburg
SAT
San Antonio
$419 Roundtrip, found 5 days ago
$419
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 25 from Harrisburg to San Antonio, returning Mon, Sep 28, priced at $419 found 5 days ago
Fri, Sep 25 - Mon, Sep 28
MDT
Harrisburg
SAT
San Antonio
$422 Roundtrip, found 5 days ago
$422
Roundtrip
found 5 days ago
Select United flight, departing Fri, Sep 25 from Harrisburg to San Antonio, returning Mon, Sep 28, priced at $422 found 5 days ago

Hotel Ideas near San Antonio Intl.

Airport Hotels near San Antonio Intl.

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$79 nightly
The price is $93 total per night from Jul 2 to Jul 3
$93 total
Jul 2 - Jul 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,876 reviews)
"Clean room"

Reviewed on Jun 29, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

3 out of 5
8818 Jones Maltsberger Rd San Antonio TX
$84 nightly
The price is $99 total per night from Jul 26 to Jul 27
$99 total
Jul 26 - Jul 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,650 reviews)
"The ac in the lobby isn’t working. Room ac wasn’t properly working as well."

Reviewed on Jun 28, 2026

Wyndham Garden San Antonio Airport
Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport

3.5 out of 5
10110 U S Hwy 281 N San Antonio TX
$103 nightly
The price is $122 total per night from Jul 5 to Jul 6
$122 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,141 reviews)
"The staff was very helpful and friendly. They have happy hour with snack and drinks in the evening. If you need a lot space or have a big family, the 2 bedroom suite with connector would be a great choice."

Reviewed on Jun 29, 2026

Embassy Suites by Hilton San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Antonio

Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
$128 nightly
The price is $151 total per night from Jul 6 to Jul 7
$151 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,818 reviews)
"The hotel is kind of old( which is very common in the area). Wonderful location, staffs are nice. Kickback is a big surprise!"

Reviewed on Jun 29, 2026

Drury Plaza Hotel San Antonio Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
$99 nightly
The price is $117 total per night from Jul 5 to Jul 6
$117 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,457 reviews)
"Great location for walking to main city attractions (Alamo, Riverwalk, market square)."

Reviewed on Jun 29, 2026

Riverwalk Plaza
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
$160 nightly
The price is $188 total per night from Jul 29 to Jul 30
$188 total
Jul 29 - Jul 30
Total with taxes and fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (2,871 reviews)
"Beautiful hotel. Would love to return sometime soon."

Reviewed on Jun 29, 2026

Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Antonio Hotels With Airport Transportation

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$84 nightly
The price is $99 total per night from Jul 6 to Jul 7
$99 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,008 reviews)
"Rooms are clean and staff are very friendly. Easy parking. Did not do breakfast. The dining area needs to remodeled."

Reviewed on Jun 27, 2026

Hampton Inn & Suites San Antonio-Airport
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3 out of 5
8505 Broadway Street San Antonio TX
$90 nightly
The price is $106 total per night from Jul 5 to Jul 6
$106 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,002 reviews)
"The staff was very unprofessional unfriendly they did not speak or acknowledge me. They were only talking negatively about me booking on a third-party site. We should not be putting the hotels out there and any deals if you’re gonna be treated this way when you get there."

Reviewed on Jun 29, 2026

Hilton Garden Inn San Antonio Airport South
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$79 nightly
The price is $93 total per night from Jul 2 to Jul 3
$93 total
Jul 2 - Jul 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,876 reviews)
"Clean room"

Reviewed on Jun 29, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Antonio Hotels

Days Inn by Wyndham San Antonio Alamo/Riverwalk

Days Inn by Wyndham San Antonio Alamo/Riverwalk

2 out of 5
400 Bowie Street San Antonio TX
$60 nightly
The price is $70 total per night from Jul 12 to Jul 13
$70 total
Jul 12 - Jul 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
7.2/10 Good! (1,582 reviews)
"The room was clean enough, but a couple of few sockets weren’t secured into the wall, which is a potential hazard, and the bathroom had damage to the floors, as if there had previously been severe water damage. The pool itself was fine. I didn’t like having to cross the street to get to the lobby ..."

Reviewed on Jun 26, 2026

Days Inn by Wyndham San Antonio Alamo/Riverwalk
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

2.5 out of 5
1011 E Houston St San Antonio TX
$58 nightly
The price is $69 total per night from Jul 2 to Jul 3
$69 total
Jul 2 - Jul 3
Total with taxes and fees
Stay at this hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (1,972 reviews)
"Bedsheets were dirty. Place is just kind of dirty overall. Staff was good though"

Reviewed on Jun 28, 2026

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
Super 8 by Wyndham Universal City

Super 8 by Wyndham Universal City

2 out of 5
200 Palisades Dr Universal City TX
$43 nightly
The price is $50 total per night from Jul 12 to Jul 13
$50 total
Jul 12 - Jul 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Universal City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Morgan's Wonderland and ...
6.8/10 (1,003 reviews)
"Fantastic"

Reviewed on Jun 13, 2026

Super 8 by Wyndham Universal City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Antonio

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
$393 nightly
The price is $465 total per night from Jul 5 to Jul 6
$465 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,006 reviews)

Families like: Outdoor pools, free waterpark access, playground, game room

Travelers say...
"We had not stayed here for quite some time. Found the property in good condition. The new Lagoon is a nice addition. The food was mostly good…exception being one dish at Charlie’s Long Bar. I understand that prices for travel have gone up BUT seems quite expensive for family travel."

Reviewed on Jun 28, 2026

Hyatt Regency Hill Country Resort and Villas
Hotel Contessa

Hotel Contessa

4 out of 5
306 W Market Street San Antonio TX
$143 nightly
The price is $169 total per night from Jul 5 to Jul 6
$169 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,680 reviews)
"The staff was outstanding"

Reviewed on Jun 29, 2026

Hotel Contessa
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
$128 nightly
The price is $151 total per night from Jul 6 to Jul 7
$151 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,818 reviews)
"The hotel is kind of old( which is very common in the area). Wonderful location, staffs are nice. Kickback is a big surprise!"

Reviewed on Jun 29, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAT Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from MDT to San Antonio Airport?
Traveling from MDT to SAT means you'll need to change planes. But hey — there's no need to worry. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from MDT to San Antonio Airport?
From Harrisburg, the wonderful sights and sounds of San Antonio are around 5 hours and 14 minutes away. Make sure you choose your favorite seat, or maybe even one with more legroom, and fly to your destination in total comfort.
How many hours flight from Harrisburg Intl. Airport to SAT?
Settle in and get comfy, because a typical plane trip from Harrisburg Intl. Airport to San Antonio Intl. Airport (SAT) is 5 hours and 19 minutes. Watch a few TV episodes, finish that book … You'll have plenty of time to sit back and enjoy the ride.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to San Antonio Intl. Airport (SAT)?
You'll need to make one or more stopovers if you're traveling from MDT to SAT. Right now, there are no airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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