Cheap flights from MDT to SAT (Harrisburg Intl. to San Antonio Intl.)

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Cheap Flights from MDT to SAT starting at $329 One Way, $339 Round Trip

Prices starting at $339 for return flights and $329 for one-way flights to San Antonio Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Dec 17 - Mon, Dec 21
MDT
Harrisburg
SAT
San Antonio
$339 Roundtrip, found 4 days ago
$339
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Dec 17 from Harrisburg to San Antonio, returning Mon, Dec 21, priced at $339 found 4 days ago
Fri, Sep 4 - Tue, Sep 15
MDT
Harrisburg
SAT
San Antonio
$344 Roundtrip, found 6 days ago
$344
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Sep 4 from Harrisburg to San Antonio, returning Tue, Sep 15, priced at $344 found 6 days ago
Fri, Sep 4 - Tue, Sep 15
MDT
Harrisburg
SAT
San Antonio
$350 Roundtrip, found 6 days ago
$350
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Sep 4 from Harrisburg to San Antonio, returning Tue, Sep 15, priced at $350 found 6 days ago
Fri, Sep 4 - Tue, Sep 15
MDT
Harrisburg
SAT
San Antonio
$364 Roundtrip, found 6 days ago
$364
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Sep 4 from Harrisburg to San Antonio, returning Tue, Sep 15, priced at $364 found 6 days ago
Thu, Dec 17 - Mon, Dec 21
MDT
Harrisburg
SAT
San Antonio
$399 Roundtrip, found 4 days ago
$399
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Dec 17 from Harrisburg to San Antonio, returning Mon, Dec 21, priced at $399 found 4 days ago

Hotel Ideas near San Antonio Intl.

Airport Hotels near San Antonio Intl.

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$80 nightly
The price is $95 total per night from Aug 16 to Aug 17
$95 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport

3 out of 5
95 NE Loop 410 San Antonio TX
$114 nightly
The price is $135 total per night from Aug 19 to Aug 20
$135 total
Aug 19 - Aug 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel San Antonio Airport
Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

3 out of 5
8818 Jones Maltsberger Rd San Antonio TX
$85 nightly
The price is $101 total per night from Aug 23 to Aug 24
$101 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Wyndham Garden San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Antonio

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
$88 nightly
The price is $104 total per night from Sep 7 to Sep 8
$104 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the breakfast ...
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
$128 nightly
The price is $151 total per night from Aug 23 to Aug 24
$151 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Drury Plaza Hotel San Antonio Riverwalk
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
$158 nightly
The price is $186 total per night from Aug 17 to Aug 18
$186 total
Aug 17 - Aug 18
Total with taxes and fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (3,012 reviews)
"We had a wonderful stay. Excellent location right next to the Riverwalk. Wonderful outdoor terrace and beautiful areas to relax. The room was nice and clean and all the staff were very helpful and polite. I definitely will stay there again and would recommend this hotel to others. Great ..."

Reviewed on Aug 14, 2026

Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Antonio Hotels With Airport Transportation

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$91 nightly
The price is $108 total per night from Aug 23 to Aug 24
$108 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,011 reviews)
"Overall excellent!"

Reviewed on Aug 14, 2026

Hampton Inn & Suites San Antonio-Airport
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3 out of 5
8505 Broadway Street San Antonio TX
$91 nightly
The price is $108 total per night from Aug 30 to Aug 31
$108 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Hilton Garden Inn San Antonio Airport South
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$80 nightly
The price is $95 total per night from Aug 16 to Aug 17
$95 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Antonio Hotels

Days Inn by Wyndham San Antonio Alamo/Riverwalk

Days Inn by Wyndham San Antonio Alamo/Riverwalk

2 out of 5
400 Bowie Street San Antonio TX
$59 nightly
The price is $69 total per night from Aug 25 to Aug 26
$69 total
Aug 25 - Aug 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
Days Inn by Wyndham San Antonio Alamo/Riverwalk
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

2.5 out of 5
1011 E Houston St San Antonio TX
$58 nightly
The price is $69 total per night from Aug 18 to Aug 19
$69 total
Aug 18 - Aug 19
Total with taxes and fees
Stay at this hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
Super 8 by Wyndham Universal City

Super 8 by Wyndham Universal City

2 out of 5
200 Palisades Dr Universal City TX
$47 nightly
The price is $54 total per night from Aug 23 to Aug 24
$54 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Universal City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Regal Live Oak and Olympia ...
7/10 Good! (1,001 reviews)
"clean , great and relaxing"

Reviewed on Aug 13, 2026

Super 8 by Wyndham Universal City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Antonio

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
$393 nightly
The price is $465 total per night from Aug 16 to Aug 17
$465 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
Hyatt Regency Hill Country Resort and Villas
Hotel Contessa

Hotel Contessa

4 out of 5
306 W Market Street San Antonio TX
$143 nightly
The price is $169 total per night from Aug 27 to Aug 28
$169 total
Aug 27 - Aug 28
Total with taxes and fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Contessa
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
$128 nightly
The price is $151 total per night from Aug 23 to Aug 24
$151 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAT Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from MDT to San Antonio Airport?
Traveling from MDT to SAT means you'll need to change planes. But hey — there's no need to worry. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from MDT to San Antonio Airport?
From Harrisburg, the wonderful sights and sounds of San Antonio are around 5 hours and 14 minutes away. Make sure you choose your favorite seat, or maybe even one with more legroom, and fly to your destination in total comfort.
How many hours flight from Harrisburg Intl. Airport to SAT?
Settle in and get comfy, because a typical plane trip from Harrisburg Intl. Airport to San Antonio Intl. Airport (SAT) is 5 hours and 19 minutes. Watch a few TV episodes, finish that book … You'll have plenty of time to sit back and enjoy the ride.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to San Antonio Intl. Airport (SAT)?
You'll need to make one or more stopovers if you're traveling from MDT to SAT. Right now, there are no airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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