Cheap flights from CAE to EYW (Columbia Metropolitan to Key West Intl.)

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Cheap Flights from CAE to EYW starting at $318 One Way, $455 Round Trip

Prices starting at $455 for return flights and $318 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 12 - Tue, Dec 15
CAE
Columbia
EYW
Key West
$455 Roundtrip, found 4 days ago
$455
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 12 from Columbia to Key West, returning Tue, Dec 15, priced at $455 found 4 days ago
Sat, Dec 12 - Tue, Dec 15
CAE
Columbia
EYW
Key West
$547 Roundtrip, found 4 days ago
$547
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 12 from Columbia to Key West, returning Tue, Dec 15, priced at $547 found 4 days ago
Sat, Dec 12 - Tue, Dec 15
CAE
Columbia
EYW
Key West
$555 Roundtrip, found 4 days ago
$555
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 12 from Columbia to Key West, returning Tue, Dec 15, priced at $555 found 4 days ago
Sat, Dec 12 - Tue, Dec 15
CAE
Columbia
EYW
Key West
$569 Roundtrip, found 4 days ago
$569
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 12 from Columbia to Key West, returning Tue, Dec 15, priced at $569 found 4 days ago
Sat, Dec 12 - Tue, Dec 15
CAE
Columbia
EYW
Key West
$611 Roundtrip, found 4 days ago
$611
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 12 from Columbia to Key West, returning Tue, Dec 15, priced at $611 found 4 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$233 nightly
The price is $262 total per night from Nov 30 to Dec 1
$262 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$188 nightly
The price is $212 total per night from Nov 30 to Dec 1
$212 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,575 reviews)
"Good"

Reviewed on Nov 9, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$165 nightly
The price is $186 total per night from Nov 17 to Nov 18
$186 total
Nov 17 - Nov 18
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,134 reviews)
"This is a very comfortable place to stay"

Reviewed on Nov 8, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
$285 nightly
The price is $321 total per night from Nov 18 to Nov 19
$321 total
Nov 18 - Nov 19
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,819 reviews)
"Awesome"

Reviewed on Nov 9, 2026

Margaritaville Beach House Key West
Havana Cabana at Key West

Havana Cabana at Key West

4 out of 5
3420 N. Roosevelt Blvd Key West FL
$197 nightly
The price is $222 total per night from Nov 29 to Nov 30
$222 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,908 reviews)
"Everything"

Reviewed on Nov 9, 2026

Havana Cabana at Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Nov 15 to Nov 16
$197 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,785 reviews)
"A+"

Reviewed on Nov 9, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$165 nightly
The price is $186 total per night from Nov 17 to Nov 18
$186 total
Nov 17 - Nov 18
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,134 reviews)
"This is a very comfortable place to stay"

Reviewed on Nov 8, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$188 nightly
The price is $212 total per night from Nov 30 to Dec 1
$212 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,575 reviews)
"Good"

Reviewed on Nov 9, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$159 nightly
The price is $178 total per night from Nov 11 to Nov 12
$178 total
Nov 11 - Nov 12
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,003 reviews)
"I really enjoyed this property. The staff was nice. The room was clean and the hotel was clean. The location was great. I did not get to use the pool or the jacuzzi, but it looked like a lot of fun and very nice area. The only reasons I gave the hotel 4 stars instead of 5 is because there was no ..."

Reviewed on Nov 8, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$184 nightly
The price is $207 total per night from Dec 1 to Dec 2
$207 total
Dec 1 - Dec 2
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$193 nightly
The price is $217 total per night from Nov 17 to Nov 18
$217 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$200 nightly
The price is $222 total per night from Nov 18 to Nov 19
$222 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,138 reviews)
"The room was ok fan was filthy. Smoke detector wasn’t blinking so it means it wasn’t working we rented a scooter and couldn’t park it on premises unless we paid $30 a day on top of our already expensive room and their was a parking lot on the premises that was completely empty not being used so we ..."

Reviewed on Nov 9, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$268 nightly
The price is $302 total per night from Nov 30 to Dec 1
$302 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,656 reviews)
"Very nice property and location. Our room was a little older but clean and had everything needed. We will be back!"

Reviewed on Nov 9, 2026

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Nov 15 to Nov 16
$197 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,785 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"A+"

Reviewed on Nov 9, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$170 nightly
The price is $191 total per night from Nov 17 to Nov 18
$191 total
Nov 17 - Nov 18
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
9/10 Wonderful! (1,796 reviews)
"Very clean room offered several different things s an Jenny at the front desk was super nice and helpful an got us some complementary cocktails"

Reviewed on Nov 9, 2026

Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CAE to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
CAE Address & GPS
Address:
125-A Summer Lake
Columbia SC, 29170
United States
IATA Code:
CAE
Longitude:
-81.119497
Latitude:
33.938804
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Columbia Metropolitan Airport to Key West Intl. Airport?
You'll have to change planes if you want to fly from Columbia Metropolitan Airport to Key West Intl. Airport. Numerous carriers operate on this route with only one stopover, including American Airlines, Delta Air Lines and KLM.
What is the shortest flight from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
Relish in an in-flight wine and settle into your seat with an interesting book or movie. With the journey from Columbia to Key West taking 4 hours and 54 minutes, you'll have enough time to kick back and enjoy the ride.
How many hours flight from CAE to EYW?
It typically takes about 5 hours to journey from CAE to Key West Intl. Airport. You'll be in the air for quite some time, so take your own entertainment, like a gripping novel or a few podcasts.
What airlines have the most flights from Columbia Metropolitan Airport to EYW?
If you're hoping to book with an airline that offers direct flights from CAE to EYW, you're out of luck. You'll need to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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