Cheap flights from BUF to EYW (Buffalo Niagara Intl. to Key West Intl.)

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Cheap Flights from BUF to EYW starting at $291 One Way, $343 Round Trip

Prices starting at $343 for return flights and $291 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 6 - Tue, Oct 13
BUF
Buffalo
EYW
Key West
$343 Roundtrip, found 6 days ago
$343
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Oct 6 from Buffalo to Key West, returning Tue, Oct 13, priced at $343 found 6 days ago
Tue, Oct 6 - Tue, Oct 13
BUF
Buffalo
EYW
Key West
$343 Roundtrip, found 6 days ago
$343
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 6 from Buffalo to Key West, returning Tue, Oct 13, priced at $343 found 6 days ago
Wed, Feb 3 - Sun, Feb 7
BUF
Buffalo
EYW
Key West
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 3 from Buffalo to Key West, returning Sun, Feb 7, priced at $363 found 1 day ago
Tue, Oct 6 - Tue, Oct 13
BUF
Buffalo
EYW
Key West
$376 Roundtrip, found 6 days ago
$376
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Oct 6 from Buffalo to Key West, returning Tue, Oct 13, priced at $376 found 6 days ago
Wed, Feb 3 - Sun, Feb 7
BUF
Buffalo
EYW
Key West
$408 Roundtrip, found 1 day ago
$408
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 3 from Buffalo to Key West, returning Sun, Feb 7, priced at $408 found 1 day ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$345 nightly
The price is $388 total per night from Jun 14 to Jun 15
$388 total
Jun 14 - Jun 15
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,100 reviews)
"The room and balcony were fantastic. The pool, grounds, and view of the ocean were lovely. The staff was super welcoming and friendly when we arrived. We enjoyed the close restaurant and walking path right across the street."

Reviewed on May 28, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$179 nightly
The price is $201 total per night from Jun 7 to Jun 8
$201 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,378 reviews)
"Clean room with great ocean view! Great breakfast with great daily variety! Great gym! Great pool with poolside shack bar and grill! Staff were great, helpful with any questions and very friendly! Van service to airport and downtown on time and great drivers! We will be back!!! 5 stars!"

Reviewed on May 31, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$177 nightly
The price is $199 total per night from Jun 28 to Jun 29
$199 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,029 reviews)
"Everything was clean, staff friendly and helpful. Shuttle system works perfectly. They have some nice handouts and warm cookies for the guests by reception. Just one inconvenience or complain - the room 377 had the worst view. I believe there were better options than a dumpster."

Reviewed on Jun 1, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$187 nightly
The price is $210 total per night from Jun 30 to Jul 1
$210 total
Jun 30 - Jul 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,324 reviews)
"Very disappointing, read why. If a hot tub/real restaurants are important/necessary to you, do not book here. They claim there is a hot tub on the premises, it is actually a 7 minute walk to a completely different hotel. (The properties are owned by the same company,this is false advertising. When ..."

Reviewed on May 31, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Jun 8 to Jun 9
$294 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,345 reviews)
"Overall, we were very happy with our stay. The staff were extremely responsive to text requests and the food and bar beverages were very good and fairly priced. My only feedback is 1 - I purposely booked this hotel because it was one of the only ones with private beach access. Unfortunately, the ..."

Reviewed on May 31, 2026

Southernmost Beach Resort and Guesthouses
Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection

3.5 out of 5
3850 N Roosevelt Blvd Key West FL
$148 nightly
The price is $167 total per night from Jun 29 to Jun 30
$167 total
Jun 29 - Jun 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy 2 restaurants, breakfast (surcharge), and a free area shuttle. Our guests praise the pool and ...
8/10 Very Good! (1,237 reviews)
"Great Stay with Excellent Shuttle Service! We recently stayed for 1 night during our Key West vacation and had a very pleasant experience overall. Location – The hotel is conveniently located close to the Key West downtown area. What really stood out was the complimentary shuttle service that runs ..."

Reviewed on Jun 1, 2026

Hilton Garden Inn Key West / The Keys Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$177 nightly
The price is $199 total per night from Jun 28 to Jun 29
$199 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,029 reviews)
"Everything was clean, staff friendly and helpful. Shuttle system works perfectly. They have some nice handouts and warm cookies for the guests by reception. Just one inconvenience or complain - the room 377 had the worst view. I believe there were better options than a dumpster."

Reviewed on Jun 1, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$179 nightly
The price is $201 total per night from Jun 7 to Jun 8
$201 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,378 reviews)
"Clean room with great ocean view! Great breakfast with great daily variety! Great gym! Great pool with poolside shack bar and grill! Staff were great, helpful with any questions and very friendly! Van service to airport and downtown on time and great drivers! We will be back!!! 5 stars!"

Reviewed on May 31, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$199 nightly
The price is $224 total per night from Jun 15 to Jun 16
$224 total
Jun 15 - Jun 16
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Super cute stay and great location!"

Reviewed on May 24, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$175 nightly
The price is $196 total per night from Jun 2 to Jun 3
$196 total
Jun 2 - Jun 3
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,340 reviews)
"The rooms are nice. They provide necessary amenities and are cleaned well. Not a lot of space, but fair for a motel setting. There is loud music next door at a bar, which I enjoyed, but that’s something to be aware of if you’re a light sleeper. The staff was helpful and this area of the island was ..."

Reviewed on May 31, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$120 nightly
The price is $135 total per night from Jun 2 to Jun 3
$135 total
Jun 2 - Jun 3
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,001 reviews)
"Clean and very good staff"

Reviewed on Jun 1, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$161 nightly
The price is $178 total per night from Jun 3 to Jun 4
$178 total
Jun 3 - Jun 4
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,035 reviews)
"I would highly recommend this hotel from the friendly staff, to the pool, lovely gardens and delicious fresh breakfast. The location is easily walkable to all of Key West attractions but very quiet and relaxing."

Reviewed on May 31, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Jun 8 to Jun 9
$294 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,345 reviews)
"Overall, we were very happy with our stay. The staff were extremely responsive to text requests and the food and bar beverages were very good and fairly priced. My only feedback is 1 - I purposely booked this hotel because it was one of the only ones with private beach access. Unfortunately, the ..."

Reviewed on May 31, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
"This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ..."

Reviewed on Apr 19, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$187 nightly
The price is $210 total per night from Jun 30 to Jul 1
$210 total
Jun 30 - Jul 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,324 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"Very disappointing, read why. If a hot tub/real restaurants are important/necessary to you, do not book here. They claim there is a hot tub on the premises, it is actually a 7 minute walk to a completely different hotel. (The properties are owned by the same company,this is false advertising. When ..."

Reviewed on May 31, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from BUF to EYW?
While you won't be able to fly direct from Buffalo Niagara International Airport to EYW, there are several companies that service this route with just a single stopover. Why not see if the dates available with American Airlines or United Airlines match your travel plans? If not, take a look at Delta Air Lines.
What is the shortest flight from BUF to Key West Intl. Airport (EYW)?
Make the most of the opportunity to chill out on the flight from Buffalo to Key West. The shortest flight time from BUF to EYW is 4 hours and 51 minutes, which gives you plenty of time to enjoy a drink or lose yourself in a good book.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport?
Get nice and comfortable, because the average plane trip from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport is 4 hours and 55 minutes. Watch a few movies, finish that book … You'll have more than enough time to sit back and enjoy the ride.
What airlines have the most flights from BUF to Key West Intl. Airport (EYW)?
Currently, there are no airlines that have direct flights between Buffalo Niagara International Airport and Key West Intl. Airport. But there's a silver lining. There are several single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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