Cheap flights from PIT to STL (Pittsburgh Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from PIT to STL starting at $78 One Way, $271 Round Trip

Prices starting at $271 for return flights and $78 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 15 - Tue, Apr 28
PIT
Pittsburgh
STL
St. Louis
$271 Roundtrip, found 2 days ago
$271
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Apr 15 from Pittsburgh to St. Louis, returning Tue, Apr 28, priced at $271 found 2 days ago
Wed, Apr 15 - Tue, Apr 28
PIT
Pittsburgh
STL
St. Louis
$281 Roundtrip, found 2 days ago
$281
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Apr 15 from Pittsburgh to St. Louis, returning Tue, Apr 28, priced at $281 found 2 days ago
Wed, Apr 15 - Tue, Apr 28
PIT
Pittsburgh
STL
St. Louis
$285 Roundtrip, found 2 days ago
$285
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Apr 15 from Pittsburgh to St. Louis, returning Tue, Apr 28, priced at $285 found 2 days ago
Wed, Apr 15 - Tue, Apr 28
PIT
Pittsburgh
STL
St. Louis
$290 Roundtrip, found 2 days ago
$290
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Apr 15 from Pittsburgh to St. Louis, returning Tue, Apr 28, priced at $290 found 2 days ago
Wed, Apr 15 - Tue, Apr 28
PIT
Pittsburgh
STL
St. Louis
$294 Roundtrip, found 2 days ago
$294
Roundtrip
found 2 days ago
Select United flight, departing Wed, Apr 15 from Pittsburgh to St. Louis, returning Tue, Apr 28, priced at $294 found 2 days ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$86 nightly
The price is $101 total per night from Apr 12 to Apr 13
$101 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,890 reviews)
We only stayed overnight to fatch a very early flight from STL airport, they offered free refreshments in the evening till 7:00pm but we did not try but was told it was very good. Bed was very comfortable abd unfortunately we did nit get to try the breakfast buffet due to a 4:30am flight, staff was ...

Reviewed on Apr 4, 2026

Pear Tree Inn St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$139 nightly
The price is $165 total per night from Apr 12 to Apr 13
$165 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,002 reviews)
The power was out in the dining area due to storms & the staff were wonderful & had an alternative setup for breakfast.

Reviewed on Apr 1, 2026

Hilton St. Louis Airport
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

3 out of 5
10490 Natural Bridge Rd St. Louis MO
$115 nightly
The price is $135 total per night from Apr 12 to Apr 13
$135 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,171 reviews)
Friendly staff, great breakfast, clean room.

Reviewed on Apr 3, 2026

Drury Inn & Suites St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$113 nightly
The price is $132 total per night from Apr 13 to Apr 14
$132 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,919 reviews)
A lot of options at breakfast but not many that fit in a wheat allergy. The staff is wonderful and the rooms were nice.

Reviewed on Apr 3, 2026

Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$154 nightly
The price is $180 total per night from Apr 12 to Apr 13
$180 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,353 reviews)
Clean roon

Reviewed on Apr 4, 2026

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$100 nightly
The price is $116 total per night from Apr 19 to Apr 20
$116 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,127 reviews)
The lobby was pretty, room was clean and comfortable.

Reviewed on Apr 4, 2026

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$66 nightly
The price is $78 total per night from May 3 to May 4
$78 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,002 reviews)
Plaster was falling off the walls, the room did not seem clean at all, and it was so bad that I went across the street to another hotel to see if they had room rooms. Unfortunately, they did not so I slept in my clothes because the sheets seemed gross.

Reviewed on Apr 2, 2026

Quality Inn Saint Louis Airport
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$158 nightly
The price is $189 total per night from Apr 11 to Apr 12
$189 total
Apr 11 - Apr 12
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8/10 Very Good! (1,001 reviews)
We didnt get the room we reserved and sleepingnon floor was very uncomfortable

Reviewed on Mar 15, 2026

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$139 nightly
The price is $165 total per night from Apr 12 to Apr 13
$165 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,002 reviews)
The power was out in the dining area due to storms & the staff were wonderful & had an alternative setup for breakfast.

Reviewed on Apr 1, 2026

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$66 nightly
The price is $78 total per night from May 3 to May 4
$78 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,002 reviews)
Plaster was falling off the walls, the room did not seem clean at all, and it was so bad that I went across the street to another hotel to see if they had room rooms. Unfortunately, they did not so I slept in my clothes because the sheets seemed gross.

Reviewed on Apr 2, 2026

Quality Inn Saint Louis Airport
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$99 nightly
The price is $116 total per night from Apr 5 to Apr 6
$116 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and Busch Stadium are located ...
Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
6.6/10 (1,000 reviews)
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...

Families like: Indoor pool, playground, game room, cribs

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$154 nightly
The price is $180 total per night from Apr 12 to Apr 13
$180 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,353 reviews)
Clean roon

Reviewed on Apr 4, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$113 nightly
The price is $132 total per night from Apr 13 to Apr 14
$132 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,919 reviews)
A lot of options at breakfast but not many that fit in a wheat allergy. The staff is wonderful and the rooms were nice.

Reviewed on Apr 3, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

PIT to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
PIT Address & GPS
Address:
1000 Airport Boulevard
Pittsburgh PA, 15231-0370
United States
IATA Code:
PIT
Longitude:
-80.25657
Latitude:
40.49585
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from Pittsburgh Intl. Airport (PIT) to St. Louis Lambert International Airport?
You won't have to bother about swapping planes or missing your next flight on this route. Southwest Airlines will fly you directly from PIT to STL.
What is the shortest flight from Pittsburgh Intl. Airport (PIT) to St. Louis Lambert International Airport?
The quickest you can fly from Pittsburgh Airport to STL is 5 hours and 9 minutes. Slip a few things into your carry-on to stop you from getting bored, like a fascinating read or your travel journal.
How many hours flight from Pittsburgh Airport to St. Louis Lambert International Airport?
It usually takes around 5 hours and 16 minutes to journey from Pittsburgh Airport to STL. You'll be in the air for a decent length of time, so consider taking plenty of entertainment, like a book or your travel journal.
What airlines have the most flights from Pittsburgh Intl. Airport (PIT) to St. Louis Lambert International Airport?
Whether you opt for aisle or window, you'll travel to your destination comfortably with Southwest Airlines. This popular air carrier has 78 flights from Pittsburgh to St. Louis each month.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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