$68 Cheap flight deals from Chicago (CHI) to Panama City (PNS)

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This Weekend's Flight Deals from Chicago to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 8 - Sat, Feb 14
ORD
O'Hare Intl.
PNS
Pensacola Intl.
$163 Roundtrip, found 4 days ago
$163
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Sun, Feb 8 from O'Hare Intl. to Pensacola Intl., returning Sat, Feb 14, priced at $163 found 4 days ago

Airfares from $68 One Way, $150 Round Trip from Chicago to Panama City

Prices starting at $150 for return flights and $68 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 28 - Wed, Mar 4
ORD
Chicago
PNS
Pensacola
$150 Roundtrip, found 1 day ago
$150
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sat, Feb 28 from Chicago to Pensacola, returning Wed, Mar 4, priced at $150 found 1 day ago
Thu, Feb 19 - Mon, Mar 2
MDW
Chicago
PNS
Pensacola
$163 Roundtrip, found 2 days ago
$163
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Feb 19 from Chicago to Pensacola, returning Mon, Mar 2, priced at $163 found 2 days ago
Wed, Apr 1 - Wed, Apr 8
ORD
Chicago
ECP
Panama City
$207 Roundtrip, found 10 hours ago
$207
Roundtrip
found 10 hours ago
Select United flight, departing Wed, Apr 1 from Chicago to Panama City, returning Wed, Apr 8, priced at $207 found 10 hours ago
Mon, Feb 23 - Fri, Feb 27
ORD
Chicago
PNS
Pensacola
$207 Roundtrip, found 1 day ago
$207
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Feb 23 from Chicago to Pensacola, returning Fri, Feb 27, priced at $207 found 1 day ago
Wed, Feb 25 - Sat, Feb 28
MDW
Chicago
ECP
Panama City
$216 Roundtrip, found 10 hours ago
$216
Roundtrip
found 10 hours ago
Select Southwest Airlines flight, departing Wed, Feb 25 from Chicago to Panama City, returning Sat, Feb 28, priced at $216 found 10 hours ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Lodge at Gulf State Park, A Hilton Hotel
4.0-star property

The Lodge at Gulf State Park, A Hilton Hotel

9.2/10 Wonderful! (1,004 reviews)

Mar 24 - Mar 28

4 night stay

Chicago (CHI) to Pensacola (PNS)

Spirit Airlines • Non-stop • Coach

Pensacola (PNS) to Chicago (CHI)

Southwest Airlines • Non-stop • Coach
Price was $1,037, price is now $783 per person
$783
per person
found 1 day ago
My new favorite place! The food options are great and the atmosphere is relaxing even when it’s busy

Reviewed on Sep 8, 2025

Portofino Island Resort
4.0-star property

Portofino Island Resort

8.8/10 Excellent! (470 reviews)

Mar 8 - Mar 14

6 night stay

Chicago (CHI) to Pensacola (PNS)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,875, price is now $1,427 per person
$1,427
per person
found 1 day ago
Beautiful location, accommodations and extremely helpful staff!

Reviewed on Mar 12, 2022

Bay Club of Sandestin
3.5-star property

Bay Club of Sandestin

9/10 Wonderful! (154 reviews)

Mar 15 - Mar 19

4 night stay

Chicago (CHI) to Fort Walton Beach (VPS)

American Airlines • Non-stop • Coach

Fort Walton Beach (VPS) to Chicago (CHI)

JetBlue Airways • Non-stop • Coach
Price was $1,147, price is now $875 per person
$875
per person
found 9 hours ago
The rooms are gorgeous and well kept and the view is to die for!

Reviewed on Dec 3, 2021

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More About Flying To Panama City from Chicago

Route Information for Flights from Chicago to Panama City

Origin Airport IATA Code
CHI
Destination Airport IATA Code
PNS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Chicago to Panama City

Looking for cheap Chicago to Panama City flights? Orbitz has the cheapest air fares for flights from Chicago to Panama City. Plus, with our cutting-edge mobile tools, travel planning has never been easier or more wallet-friendly.

Mobile Deals and Steals

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Book Hotels With Confidence

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Access Your Flight Information Anytime

Use the Orbitz app or the mobile Orbitz site, m.orbtiz.com, to see information about your Chicago to Panama City flights anytime you need it. Your itinerary is also sent to your email address for reference. Access updates on your flights from Chicago to Panama City on your mobile device too, including delays and baggage claim details.

Cheap Air Ticket Prices Guaranteed

Orbitz is your number one source for low fares for Chicago to Panama City flights. Our low price guarantee on domestic and international air tickets give you great savings for a perfect trip to Panama City. Need hotels too? You can book them last minute on your mobile phone.

Frequently asked questions

Are there non-stop flights from Chicago to Panama City?
There sure are, which is great news if you're not a massive fan of swapping planes en route. United Airlines and American Airlines offer direct flights from ORD to Pensacola Airport.
What is the shortest flight from Chicago to Panama City?
If the weather is good and there are no unexpected hiccups, you could be stepping off the plane at Pensacola Intl. Airport (PNS) from ORD in only 2 hours and 45 minutes. With such a brief flight time, contemplate traveling with hand luggage only.
What airlines fly from Chicago to Panama City most frequently?
There are two airlines offering the most frequent flights from O'Hare Intl. Airport (ORD) to Pensacola Intl. Airport (PNS), including United Airlines (UA). Popular with travelers, it operates 30 flights on this route each month. If you can't find the right flight for you there, look up American Airlines (AA). This airline is a terrific alternative and operates 30 flights between Chicago and Panama City each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.