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Serenity South -- Gardens, River-Views, and Refreshing Space

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Dining
3 bedrooms, iron/ironing board, WiFi, bed sheets
Terrace/patio
Dining
Terrace/patio

Reviews

10 out of 10
Exceptional

Entire home

3 bedrooms2 bathroomsSleeps 51600 sq ft

Popular amenities

  • Kitchen
  • Outdoor Space
  • Parking available
  • Fireplace

Explore the area

View in a map
Cape Girardeau, MO
  • Place, Riverfront Park
    ‪2 min walk‬
  • Place, Riverfront Bridge Park
    ‪5 min walk‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪19 min walk‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪8 min drive‬

Room options

About the neighborhood

Cape Girardeau

This vacation home places you next to Mississippi River and eDen Spa & Salon. The vacation home includes a kitchen, a fireplace, and a balcony.
View more Vacation Homes in Cape GirardeauOpens in a new window

What's nearby

  • eDen Spa & Salon - 2 min walk - 0.1 miles
  • Riverfront Park - 2 min walk - 0.1 miles
  • Riverfront Bridge Park - 5 min walk - 0.3 miles
  • Century Casino & Hotel Cape Girardeau - 19 min walk - 1.0 mile
  • Southeast Missouri State University - 2 min drive - 1.1 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 12 min drive

Restaurants

  • ‪Sand's Pancake House - ‬11 min walk
  • ‪Greens Garden Urban Market + Kitchen - ‬5 min walk
  • ‪Minglewood Brewery - ‬7 min walk
  • ‪Speck - ‬11 min walk
  • ‪Port Cape Girardeau - ‬7 min walk

About this property

Entire place

You'll have the entire home to yourself and will only share it with other guests in your party.

Serenity South -- Gardens, River-Views, and Refreshing Space

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.
The vacation home is air-conditioned and features a kitchen, 1.5 bathrooms, and a balcony. There's space to spread out with 3 bedrooms and a dining area. Guests can expect to find a TV with a DVD player. Other standard amenities include a fireplace, a coffee maker, and an ironing board.

Similar properties

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
  • Pool
  • Hot tub
  • Breakfast included
  • Pet friendly
9.6 out of 10, Exceptional, 1,001 reviews
$100 nightly
The price is $113
May 31 - Jun 1
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Internet

  • Available in the house: WiFi

Parking and transportation

  • Car not required
  • Parking on site

Kitchen

  • Coffee grinder
  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Ice maker
  • Microwave
  • Oven
  • Paper towels
  • Refrigerator
  • Spices
  • Stovetop
  • Toaster

Bedrooms

  • 3 bedrooms
  • Bedsheets provided

Bathroom

  • 1.5 bathrooms
  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Living spaces

  • Fireplace
  • Living room
  • Separate dining area

Entertainment

  • Books
  • DVD player
  • Games
  • TV

Outdoor areas

  • Balcony
  • Garden
  • Outdoor furniture

Laundry

  • Laundromat nearby

Comfort

  • Air conditioning
  • Heating

Pets

  • No pets allowed

Suitability/Accessibility

  • Smoking not allowed

Services and conveniences

  • Iron/ironing board

Location highlights

  • Near a health/beauty spa
  • Near a hospital
  • Near an outlet shopping mall
  • On a river

Things to do

  • Basketball nearby
  • Casino nearby
  • Cycling nearby
  • Fishing nearby
  • Golfing nearby
  • Hiking/biking trails nearby
  • Horseback riding nearby
  • Motor boating nearby
  • Swimming nearby
  • Wildlife walks nearby
  • Winery tours nearby

Safety features

  • Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
  • Smoke detector (host has indicated there is a smoke detector on the property)
  • Deadbolt lock

General

  • Garden
  • Unit size: 1,600 square feet

Policies

Check-in

Check-in time starts at 4:00 PM
Minimum check-in age: 18

Check-out

Check-out before 11:00 AM

Special check-in instructions

You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools

Rules

Back yard is shared with the other side of the duplex. Please respect their use of the common space.

Pets

  • This property doesn't allow pets

Children and extra beds

  • Note from host: Excellent fenced back yard.

Events

Events allowed: family gatherings, birthday parties, weddings
Parties or events must okayed before arrival.

Smoking

Smoking is not permitted

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Parties and events (including family gatherings, birthday parties and weddings) are allowed on site; maximum attendees: 50
Note from host: Parties or events must okayed before arrival.
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
  • Check-in: 4:00 PM
  • Check-out: 11:00 AM
  • Minimum check-in age: 18

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • Parties and events (including family gatherings, birthday parties and weddings) are allowed on site. Maximum attendees: 50.
  • Note from host: Parties or events must okayed before arrival.
  • Onsite safety features include a carbon monoxide detector, a smoke detector, and a deadbolt lock.

Frequently asked questions

What is there to do near this vacation home?

This vacation home is located in Cape Girardeau, just steps from Mississippi River and Shawnee National Forest, and within a short walk of Riverfront Bridge Park. You'll also find Riverfront Park and eDen Spa & Salon less than a mile away.

How much does it cost to stay at Serenity South -- Gardens, River-Views, and Refreshing Space?

As of May 23, 2026, prices found for a 1-night stay for 2 adults at Serenity South -- Gardens, River-Views, and Refreshing Space on May 25, 2026 start from $248, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Will I be able to park at Serenity South -- Gardens, River-Views, and Refreshing Space?

No, this vacation home doesn't offer parking.

Is this vacation home adjacent to a casino?

No, this vacation home is not connected to a casino.

Will I find an indoor pool at this vacation home?

No, there is no indoor pool at this vacation home.

Is Serenity South -- Gardens, River-Views, and Refreshing Space good for couples?

Amenities that appeal to couples at this riverfront vacation home include a fireplace and a kitchen along with a garden.

Are there hot tubs at Serenity South -- Gardens, River-Views, and Refreshing Space?

No, this vacation home doesn't have a spa tub.

Does this vacation home include breakfast service?

No, this vacation home doesn't offer breakfast.

Will this vacation home allow pets to stay free of charge?

No, pets aren't allowed at this vacation home.

Are there connecting rooms at Serenity South -- Gardens, River-Views, and Refreshing Space?

No, there aren't connecting guestrooms at this vacation home.

How close is the airport from this vacation home?

The closest major airport to this vacation home is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 7.4 mi away (12 minutes by car). Another top airport is Cairo, IL (CIR-Cairo Regional), which is located 28.1 mi away (42-minute drive).

Can I book a room with a balcony at Serenity South -- Gardens, River-Views, and Refreshing Space?

Yes, every house at Serenity South -- Gardens, River-Views, and Refreshing Space comes with a balcony.

Serenity South -- Gardens, River-Views, and Refreshing Space Reviews

Reviews

10

Exceptional

Rating 10 - Excellent. 150 out of 155 reviews
Rating 8 - Good. 5 out of 155 reviews
Rating 6 - Okay. 0 out of 155 reviews
Rating 4 - Poor. 0 out of 155 reviews
Rating 2 - Terrible. 0 out of 155 reviews

10/10

Cleanliness

10/10

Property conditions & facilities

Reviews

10/10 Excellent

Debbie M.

Liked: Cleanliness
What a wonderful stay! Everything you need (and more) is available, and everything was easy to find. Loved having coffee on the upstairs balcony! We'll be back!
Stayed 2 nights in May 2026

10/10 Excellent

John H.

Liked: Cleanliness
Nice place. I’d stay there again.
Stayed 2 nights in Apr 2026

10/10 Excellent

Sandy S.

Liked: Cleanliness
although short, stay was enjoyable and comfortable..Really nice neighbors and neighborhood..ease to walk to park for the grand kids to play and easy access to restaurants near by all within walking distance.
Stayed 2 nights in Apr 2026

10/10 Excellent

John M.

Liked: Cleanliness
This is a beautiful, well-maintained historic home in a neat part of town -- walking distance to lots of attractions. The hospitality was off the charts. Every detail was thought out. Bed was comfortable, AC worked great, and wonderful spaces (dining room, living room, porch) to hang out in!
Stayed 2 nights in Mar 2026

10/10 Excellent

Marcie R.

Liked: Cleanliness
Nice location to river front and downtown. Very lovely place.
Stayed 1 night in Feb 2026

10/10 Excellent

Vicki R.

Liked: Cleanliness
It's a great location, great space, great price. And, the muffins are the best!
Stayed 1 night in Dec 2025

8/10 Good

Tamy R.

Liked: Cleanliness
Host was fantastic. House is just like the pictures.
Stayed 2 nights in Dec 2025

10/10 Excellent

Alison C.

Liked: Cleanliness
Wonderful location! WonderfulStay
Stayed 1 night in Nov 2025

10/10 Excellent

Amy G.

Liked: Cleanliness
Stayed 1 night in Oct 2025

8/10 Good

Michael W.

Liked: Cleanliness
All was good except for the strange fact of 3 rentals at the same place and the older couple in the backyard was a little off putting.
Stayed 1 night in Oct 2025

10/10 Excellent

Isaac S.

Liked: Cleanliness
Home was very tidy, kitchen was spacious, and bedrooms comfortable.
Stayed 2 nights in Oct 2025

10/10 Excellent

Michael R., St. Louis, MO

Liked: Cleanliness
Nice property near downtown in the river. This was the perfect location for our 50th high school reunion.
Stayed 2 nights in Oct 2025

10/10 Excellent

Shelley L.

Liked: Cleanliness
Good stay.
Stayed 1 night in Sep 2025

10/10 Excellent

Sandy M.

Liked: Cleanliness
We were visiting our daughter who attends SEMO, so the location was perfect.
Stayed 3 nights in Sep 2025

10/10 Excellent

Deborah K., Little Rock, USA

Liked: Cleanliness
Charming house within walking distance to downtown restaurants and bars. Host is wonderful! Great communication.
Stayed 1 night in Sep 2025

10/10 Excellent

Donna D.

Liked: Cleanliness

Lovely as always

Moving our daughter in to the dorm at SEMO for yr 2. Been coming to this location since our trip here during her senior year of HS when she visited SEMO to audition for the musical theatre program. It is a great place to stay when you have more than 2 people.
Stayed 1 night in Aug 2025

10/10 Excellent

Tracy H., Lodi

Liked: Cleanliness
Such a great place and location
Stayed 2 nights in Jul 2025

10/10 Excellent

Jodie F., Overland Park Ks

Liked: Cleanliness
Enjoyed everything! Great location!
Stayed 4 nights in Jul 2025

10/10 Excellent

Nichole C.

Liked: Cleanliness
Serenity south was welcoming comfortable and very clean. Impeccably maintained historic home. Comfortable beds, great water pressure and shower head, easy to maintain consistent temperature. Good vibes throughout. Not haunted. Beautiful outdoor space but it was too hot to use it much while we were there. Recommend stopping by the olive oil store William and Water across the street.
Stayed 3 nights in Jul 2025

10/10 Excellent

Mark H.

Liked: Cleanliness
Stayed 2 nights in Jun 2025

10/10 Excellent

Bryan P.

Liked: Cleanliness

Comfortable & Clean

Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend it with 5 Stars!
Stayed 1 night in Jun 2025

10/10 Excellent

Vicki R.

Liked: Cleanliness
Beautiful house. Great stay. Would definitely stay again!
Stayed 1 night in Jun 2025

10/10 Excellent

Linden S.

Liked: Cleanliness

A Beautiful Retreat for Three Generations

Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay.
Stayed 2 nights in May 2025

10/10 Excellent

STEPHANIE L.

Liked: Cleanliness

In town for one day

Its was different, but over all it was on point.I will rebook this summer
Stayed 1 night in May 2025

10/10 Excellent

Sam E.

Liked: Cleanliness

Downtown home with great character

My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.
Stayed 1 night in Apr 2025

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