Cheap flights from ROA to SAT (Roanoke Regional to San Antonio Intl.)

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Cheap Flights from ROA to SAT starting at $276 One Way, $257 Round Trip

Prices starting at $257 for return flights and $276 for one-way flights to San Antonio Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 1 - Tue, Apr 7
ROA
Roanoke
SAT
San Antonio
$257 Roundtrip, found 3 days ago
$257
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 1 from Roanoke to San Antonio, returning Tue, Apr 7, priced at $257 found 3 days ago
Mon, Mar 30 - Tue, Apr 7
ROA
Roanoke
SAT
San Antonio
$258 Roundtrip, found 3 days ago
$258
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Mar 30 from Roanoke to San Antonio, returning Tue, Apr 7, priced at $258 found 3 days ago
Tue, Mar 10 - Mon, Mar 16
ROA
Roanoke
SAT
San Antonio
$261 Roundtrip, found 2 days ago
$261
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Mar 10 from Roanoke to San Antonio, returning Mon, Mar 16, priced at $261 found 2 days ago
Wed, Mar 4 - Thu, Mar 12
ROA
Roanoke
SAT
San Antonio
$264 Roundtrip, found 2 days ago
$264
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Mar 4 from Roanoke to San Antonio, returning Thu, Mar 12, priced at $264 found 2 days ago
Mon, Mar 9 - Mon, Mar 16
ROA
Roanoke
SAT
San Antonio
$265 Roundtrip, found 2 days ago
$265
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Mar 9 from Roanoke to San Antonio, returning Mon, Mar 16, priced at $265 found 2 days ago

Hotel Ideas near San Antonio Intl.

Airport Hotels near San Antonio Intl.

Wyndham Garden San Antonio Airport Northeast

Wyndham Garden San Antonio Airport Northeast

3 out of 5
8818 Jones Maltsberger Rd San Antonio TX
$89 nightly
The price is $106 total per night from Jan 27 to Jan 28
$106 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,137 reviews)
Room was great beds were very nice. Restroom was great and spacious look very nice with the nuce tile on wall and floor. Breakfast wasn't very good eggs were very bland no flavor gravy was bland no flavor that is because my husband likes just about anything he said no flavor he did not eat them. ...

Reviewed on Jan 23, 2026

Wyndham Garden San Antonio Airport Northeast
Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$83 nightly
The price is $98 total per night from Feb 1 to Feb 2
$98 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (1,878 reviews)
Room was great size for what we needed. Hotel was warm and very welcoming.

Reviewed on Jan 26, 2026

Hampton Inn & Suites San Antonio-Airport
Crowne Plaza San Antonio Airport by IHG

Crowne Plaza San Antonio Airport by IHG

3.5 out of 5
1111 NE Loop 410 San Antonio TX
$70 nightly
The price is $83 total per night from Feb 3 to Feb 4
$83 total
Feb 3 - Feb 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,531 reviews)
Room was clean and didn't smell like smoke

Reviewed on Jan 25, 2026

Crowne Plaza San Antonio Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Antonio

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
$142 nightly
The price is $166 total per night from Feb 1 to Feb 2
$166 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,415 reviews)
Very pleasant employees. Room quality was very nice. Dorrego’s restaurant was very good. The bar wait staff, including Lainy, were very efficient. A very nice facility with a great location on the Riverwalk.

Reviewed on Jan 23, 2026

Hotel Valencia Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
$124 nightly
The price is $147 total per night from Feb 1 to Feb 2
$147 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (3,739 reviews)
Historical hospitality! Great hotel!

Reviewed on Jan 22, 2026

Menger Hotel
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
$88 nightly
The price is $104 total per night from Feb 8 to Feb 9
$104 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (3,851 reviews)
Old facility

Reviewed on Jan 21, 2026

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Antonio Hotels With Airport Transportation

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$83 nightly
The price is $98 total per night from Feb 1 to Feb 2
$98 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (1,878 reviews)
Room was great size for what we needed. Hotel was warm and very welcoming.

Reviewed on Jan 26, 2026

Hampton Inn & Suites San Antonio-Airport
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3 out of 5
8505 Broadway Street San Antonio TX
$86 nightly
The price is $101 total per night from Feb 1 to Feb 2
$101 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.2/10 Very Good! (1,000 reviews)
Staff is great and amenities were good

Reviewed on Jan 13, 2026

Hilton Garden Inn San Antonio Airport South
Heritage Inn Suites San Antonio Airpt, Trademark by Wyndham

Heritage Inn Suites San Antonio Airpt, Trademark by Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$79 nightly
The price is $93 total per night from Jan 27 to Jan 28
$93 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,551 reviews)
Found someones sock on the floor. Beds springy. Staff was excellent!

Reviewed on Jan 20, 2026

Heritage Inn Suites San Antonio Airpt, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Antonio Hotels

Days Inn by Wyndham San Antonio Alamo/Riverwalk

Days Inn by Wyndham San Antonio Alamo/Riverwalk

2 out of 5
400 Bowie Street San Antonio TX
$58 nightly
The price is $67 total per night from Jan 27 to Jan 28
$67 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
7/10 Good! (1,336 reviews)
Clean room and heat worked just fine

Reviewed on Jan 20, 2026

Days Inn by Wyndham San Antonio Alamo/Riverwalk
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

2.5 out of 5
1011 E Houston St San Antonio TX
$45 nightly
The price is $53 total per night from Feb 1 to Feb 2
$53 total
Feb 1 - Feb 2
Total with taxes and fees
Stay at this hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (1,817 reviews)
Clean room and respectful staff

Reviewed on Jan 9, 2026

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
Super 8 by Wyndham Universal City

Super 8 by Wyndham Universal City

2 out of 5
200 Palisades Dr Universal City TX
$43 nightly
The price is $50 total per night from Feb 2 to Feb 3
$50 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Universal City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Regal Live Oak and Olympia ...
6.6/10 (1,002 reviews)
Quiet comfortable housekeeping cleans everyday , great location

Reviewed on Jan 23, 2026

Super 8 by Wyndham Universal City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Antonio

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
$329 nightly
The price is $389 total per night from Feb 1 to Feb 2
$389 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)

Families like: Outdoor pools, free waterpark access, playground, game room

Travelers say...
Yes everything was perfect.

Reviewed on Jan 14, 2026

Hyatt Regency Hill Country Resort and Villas
Hotel Contessa

Hotel Contessa

4 out of 5
306 W Market Street San Antonio TX
$176 nightly
The price is $208 total per night from Feb 8 to Feb 9
$208 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (3,459 reviews)
We always the love the hotel location and friendly staff

Reviewed on Jan 25, 2026

Hotel Contessa
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
$120 nightly
The price is $142 total per night from Feb 8 to Feb 9
$142 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,250 reviews)
Very courteous and felt like family!

Reviewed on Jan 24, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ROA to SAT Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Roanoke–Blacksburg Regional Airport to San Antonio Intl. Airport (SAT)?
While you won't be able to fly nonstop from Roanoke–Blacksburg Regional Airport to San Antonio Airport, there are several air carriers that service this route with only one stopover. Why not check if the dates and times available with Delta Air Lines or United Airlines match your travel plans? If they don't, you could always try American Airlines.
What is the shortest flight from Roanoke–Blacksburg Regional Airport to San Antonio Intl. Airport (SAT)?
Use the opportunity to relax on your journey from Roanoke to San Antonio. The shortest flight time from ROA to San Antonio Airport is 4 hours and 50 minutes, which gives you loads of time to enjoy a beverage or get absorbed in a good book.
How many hours flight from Roanoke Regional Airport (ROA) to San Antonio Intl. Airport (SAT)?
It typically takes about 4 hours and 55 minutes to jet from Roanoke–Blacksburg Regional Airport to San Antonio Airport. You'll be in the air for quite some time, so bring plenty of entertainment, like an engrossing book or your travel journal.
What airlines have the most flights from Roanoke–Blacksburg Regional Airport to SAT?
You won't find any airlines that operate direct flights between ROA and SAT. Be organized and secure a multi-stop or one-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.