Cheap flights from FSD to EYW (Sioux Falls Regional to Key West Intl.)
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Cheap Flights from FSD to EYW starting at $386 One Way, $553 Round Trip
Prices starting at $553 for return flights and $386 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
FSD
Sioux Falls
EYW
Key West
$553 Roundtrip, found 6 days ago
$553
Roundtrip
found 6 days ago
FSD
Sioux Falls
EYW
Key West
$608 Roundtrip, found 6 days ago
$608
Roundtrip
found 6 days ago
FSD
Sioux Falls
EYW
Key West
$679 Roundtrip, found 3 days ago
$679
Roundtrip
found 3 days ago
FSD
Sioux Falls
EYW
Key West
$685 Roundtrip, found 6 days ago
$685
Roundtrip
found 6 days ago
FSD
Sioux Falls
EYW
Key West
$690 Roundtrip, found 6 days ago
$690
Roundtrip
found 6 days ago
Hotel Ideas near Key West Intl.
Airport Hotels near Key West Intl.
Hyatt Vacation Club at Windward Pointe, Key West
3675 South Roosevelt Boulevard Key West FL
$207 nightly
The price is $233 total per night from Sep 22 to Sep 23
$233 total
Sep 22 - Sep 23
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$139 nightly
The price is $156 total per night from Sep 20 to Sep 21
$156 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,491 reviews)
"This hotel will definitely be our go to whenever we are in key west! A free shuttle to and from Duval every 45 minutes, FREE bottled water! Staff was super nice and knew all the best spots to eat at, our room was beautiful and super quiet, great drinks at the tiki bar next to the pool overall just ..."
Reviewed on Sep 7, 2026
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$140 nightly
The price is $157 total per night from Sep 15 to Sep 16
$157 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$210 nightly
The price is $237 total per night from Sep 13 to Sep 14
$237 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,584 reviews)
"This was a first trip to the keys and the southernmost resort was highly recommended by friends and internet....and it definitely held up to expectations! From to the room to the pools/bars everything was great! Can't wait to plan our next trip. Highly recommend the sandbar excursion for any first ..."
Reviewed on Sep 7, 2026
Beachside Resort & Residences
3841 N Roosevelt Blvd Key West FL
$188 nightly
The price is $212 total per night from Oct 4 to Oct 5
$212 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (2,501 reviews)
"The rooms and the location are nice, but do not expect a private beach access even if advertised. The beach is tiny, the rest has sand on it but isn't a beach. The elevator was out of service. The exhaust fan was broken, the toilet clogged, and the drier was making a very loud noise and wasnt working ..."
Reviewed on Sep 7, 2026
Margaritaville Beach House Key West
2001 South Roosevelt Blvd Key West FL
$234 nightly
The price is $263 total per night from Sep 21 to Sep 22
$263 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,804 reviews)
"We stayed at Margaritaville Beach House Key West to celebrate my daughter’s birthday after having a great experience at Margaritaville Hollywood Beach last year. Unfortunately, the difference was huge. The room was okay, but it was at the back of the property, making it a long walk to the pool and ..."
Reviewed on Sep 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Hotels With Airport Transportation
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$140 nightly
The price is $157 total per night from Sep 15 to Sep 16
$157 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$139 nightly
The price is $156 total per night from Sep 20 to Sep 21
$156 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,491 reviews)
"This hotel will definitely be our go to whenever we are in key west! A free shuttle to and from Duval every 45 minutes, FREE bottled water! Staff was super nice and knew all the best spots to eat at, our room was beautiful and super quiet, great drinks at the tiki bar next to the pool overall just ..."
Reviewed on Sep 7, 2026
Eden House
1015 Fleming St Key West FL
$142 nightly
The price is $160 total per night from Sep 8 to Sep 9
$160 total
Sep 8 - Sep 9
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,004 reviews)
"Loved the key west aesthetic that managed to feel like you were staying in a home vs a hotel. The outdoor pool was very clean and the bar drinks were good. Huge bonus that they let you use the pool and hot tub 24 hours a day. We needed a cell phone delivered and the staff was super helpful and on ..."
Reviewed on Sep 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Key West Hotels
Southwinds Motel
1321 Simonton Street Key West FL
$155 nightly
The price is $174 total per night from Sep 8 to Sep 9
$174 total
Sep 8 - Sep 9
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,377 reviews)
"It was small and old fashioned, but it had an old Florida vibe that we loved. Everything we needed was there. The staff were very helpful."
Reviewed on Sep 5, 2026
Seashell Motel
718 South Street Key West FL
$87 nightly
The price is $98 total per night from Sep 9 to Sep 10
$98 total
Sep 9 - Sep 10
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,003 reviews)
"Perfect"
Reviewed on Sep 6, 2026
Duval House
815 Duval St Key West FL
$119 nightly
The price is $131 total per night from Sep 8 to Sep 9
$131 total
Sep 8 - Sep 9
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$210 nightly
The price is $237 total per night from Sep 13 to Sep 14
$237 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,584 reviews)
"This was a first trip to the keys and the southernmost resort was highly recommended by friends and internet....and it definitely held up to expectations! From to the room to the pools/bars everything was great! Can't wait to plan our next trip. Highly recommend the sandbar excursion for any first ..."
Reviewed on Sep 7, 2026
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$160 nightly
The price is $180 total per night from Sep 8 to Sep 9
$180 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,659 reviews)
Families like: Outdoor pools, playground, miniature golf, game room
Travelers say...
"The entire staff was friendly, attentive and helpful at all times. Everything was clean and organized. The location was great with easy access to beaches and downtown. We really enjoyed our stay and will visit again in the future."
Reviewed on Sep 7, 2026
Hilton Key West Resort & Marina
5950 Peninsular Avenue Key West FL
$167 nightly
The price is $188 total per night from Sep 16 to Sep 17
$188 total
Sep 16 - Sep 17
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
FSD to EYW Route Info
Origin Airport | |
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Destination Airport | |
Number Of Airlines Serving | |
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Shortest Flight Departure Time | |
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- Airport Locations
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FSD Address & GPS
Address:
2801 Jaycee Lane
Sioux Falls SD, 57104
United States
IATA Code:
FSD
Longitude:
-96.741849
Latitude:
43.58201
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
Other Flights from Sioux Falls Regional Airport (FSD)
Other Flights to Key West Intl. Airport (EYW)
Top Trending
Flights
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Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
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