$252 Cheap flight deals from St. Louis (STL) to Lower Keys (EYW)
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This Weekend's Flight Deals from St. Louis to Lower Keys
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $252 One Way, $303 Round Trip from St. Louis to Lower Keys
Prices starting at $303 for return flights and $252 for one-way flights to Lower Keys were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Lower Keys economy flight packages
Coconut Beach Resort
Sep 25 - Sep 28
St. Louis (STL) to Key West (EYW)
Reviewed on Aug 19, 2026
The Key West Hotel
Oct 10 - Oct 14
St. Louis (STL) to Key West (EYW)
Reviewed on Aug 20, 2026
Duval Breeze by Avantstay Great Location Close to Beach & Nightlife Shared Pool! Week Long Stays
Oct 14 - Oct 20
St. Louis (STL) to Key West (EYW)
Reviewed on Jul 26, 2026
More About Flying To Lower Keys from St. Louis
Route Information for Flights from St. Louis to Lower Keys
Origin Airport IATA Code | STL |
|---|---|
Destination Airport IATA Code | EYW |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
St. Louis to Lower Keys
Whether you want to book cheap flights from St. Louis to Lower Keys or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for St. Louis to Lower Keys flights.
Make the Most of Your Vacation
Not only does Orbitz have cheap deals for St. Louis to Lower Keys flights, we can also help you plan your vacation in advance. Why wait in lengthy lines for tickets to shows, amusement parks, and other attractions when you could be making the most of your holiday? Add activities to your flight booking for fewer hassles once you arrive in Lower Keys.
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Craft Your Perfect Vacation
Orbitz takes the stress out of vacation planning with great deals on flights from St. Louis to Lower Keys, hotels, car rentals, cruises, and more. Mix and match results for your perfect trip, or book a complete vacation package.
Keep Informed With Orbitz
With Orbitz’s free alerts service, you will stay informed of flight or services disruptions to your St. Louis to Lower Keys flights. The alerts can be sent straight to your mobile phone or email.
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St. Louis Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.