$59 Cheap flight deals from Chicago (CHI) to Sikeston (STL)
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This Weekend's Flight Deals from Chicago to Sikeston
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $59 One Way, $117 Round Trip from Chicago to Sikeston
Prices starting at $117 for return flights and $59 for one-way flights to Sikeston were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sikeston economy flight packages
Hampton Inn By Hilton St Louis Airport
Oct 16 - Oct 18
Chicago (CHI) to St. Louis (STL)
St. Louis (STL) to Chicago (CHI)
Reviewed on Sep 11, 2026
More About Flying To Sikeston from Chicago
Route Information for Flights from Chicago to Sikeston
Origin Airport IATA Code | CHI |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Chicago to Sikeston
Orbitz guarantees you low prices on flights from Chicago to Sikeston. In addition to low fares on Chicago to Sikeston flights, Orbitz offers fantastic savings on hotels, cruises, vacation packages, and more.
Earn Miles While Saving
Besides helping you fly for the lowest fares, Orbitz lets you earn miles for your frequent flyer program for certain flights from Chicago to Sikeston. If you are a member of the frequent flyer or loyalty program offered by the airline you booked through Orbitz or a partner airline’s, simply add your frequent flyer number to your Orbitz reservation to get credit for your Chicago to Sikeston flights.
Travel Planning Made Easy
We help take some of the anxiety out of your Chicago to Sikeston flights with free flight alerts. We will let you know of flight changes and delays to your flights from Chicago to Sikeston by email, voicemail, or text messages to your mobile phone. Alerts can also be sent to up to six other contacts to keep family and business teams informed.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.