Hotels in Matthews
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Top Rated Matthews Hotels

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.63 mi from city center
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.65 mi from city center
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.55 mi from city center
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and a business center.

Hampton Inn Sikeston
1240 Commerce Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
6.82 mi from city center
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.49 mi from city center
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.

Dexter Inn
1807 W Business US Highway 60, Dexter, MO
Free Cancellation
Reserve now, pay when you stay
22.47 mi from city center
Guests of Dexter Inn enjoy access to free WiFi in public areas, meeting rooms, and a seasonal outdoor pool. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area, laundry facilities, and a vending machine.
Fairfield by Marriott Inn & Suites Sikeston
1239 Commerce Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
6.63 mi from city center
Guests of Fairfield by Marriott Inn & Suites Sikeston enjoy an indoor pool, free WiFi in public areas, and coffee in a common area. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. This hotel also has laundry facilities.

Country Yard Inn and Suite
110 South Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.69 mi from city center
At Country Yard Inn and Suite, guests have access to free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr, Sikeston, MO
6.86 mi from city center
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.

Quality Inn Charleston - Sikeston
102 Drake St, I-57 Exit 10, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
16.63 mi from city center
Guests of Quality Inn Charleston - Sikeston enjoy free WiFi in public areas, a business center, and a vending machine. A stay here includes free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly

Comfort Inn & Suites Sikeston I-55
109 Matthews Ln, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
9.45 mi from city center
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center and laundry facilities.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What's the best place for a stay in Matthews?
What are some of the best hotels in Matthews?
Here are some top hotels in Matthews:
- Best Western Plus Sikeston is located 9.6 mi away, and this hotel has free breakfast, free parking, and a fitness center.
- Drury Inn & Suites Sikeston, MO is located 9.7 mi away, and this hotel has free breakfast, free WiFi, and free parking.
- Pear Tree Inn Sikeston is located 9.6 mi away, and this hotel has free breakfast, free WiFi, and a fitness center.
Matthews hotels essential information
Accommodation | 35 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Best Western Plus Sikeston, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Hampton Inn Sikeston, Days Inn and Suites by Wyndham Sikeston, Dexter Inn, Fairfield by Marriott Inn & Suites Sikeston, Country Yard Inn and Suite, Holiday Inn Express & Suites Sikeston Southwest by IHG, Quality Inn Charleston - Sikeston, Comfort Inn & Suites Sikeston I-55, New Orleans Inn Portageville |
Recent Reviews

Drury Inn & Suites Sikeston, MO
5/5 Excellent
Nice place to stop.
"Nice, clean hotel. It’s a very small town, but there is fast food nearby and close to the interstate. We made a quick one night stop but enjoyed the indoor/outdoor pool and indoor hot tub. The parking lot was very wel lit and the area felt safe. "
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 3 days ago
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