$69 Cheap flight deals from Chicago (CHI) to Sikeston (STL)
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This Weekend's Flight Deals from Chicago to Sikeston
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $69 One Way, $139 Round Trip from Chicago to Sikeston
Prices starting at $139 for return flights and $69 for one-way flights to Sikeston were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sikeston economy flight packages
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Jun 5 - Jun 7
Chicago (CHI) to St. Louis (STL)
St. Louis (STL) to Chicago (CHI)
Reviewed on Jan 18, 2026
The Wildwood Hotel
Jun 11 - Jun 14
Chicago (CHI) to St. Louis (STL)
St. Louis (STL) to Chicago (CHI)
Reviewed on Feb 24, 2026
Sikeston first class flight packages
Ameristar Casino Resort and Spa
Jun 5 - Jun 7
Chicago (ORD) to St. Louis (STL)
Reviewed on Dec 2, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Jun 5 - Jun 7
Chicago (ORD) to St. Louis (STL)
Reviewed on Jan 18, 2026
Hilton St. Louis at the Ballpark
Jun 5 - Jun 7
Chicago (ORD) to St. Louis (STL)
Reviewed on Feb 19, 2026
More About Flying To Sikeston from Chicago
Route Information for Flights from Chicago to Sikeston
Origin Airport IATA Code | CHI |
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Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Chicago to Sikeston
Orbitz has your best deals on Chicago to Sikeston flights. From guaranteed low prices to cutting-edge mobile tools, the perfect trip begins on Orbitz.
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Budget Travel Planning Made Easy
It's easy to find discount air tickets for flights from Chicago to Sikeston on Orbitz. Mix and match airlines for your departing and your returning flights to find the lowest fares and the best schedule.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.