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Casino Hotels in Sikeston, MO

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Featured Sikeston Casino Resorts & Hotels

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $56 per night
At Town House Inn Cape Giradreau, guests have access to free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Free Cancellation
The price is $103 per night
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, guests enjoy features like an indoor pool, a fitness center, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a meeting room, a business center, and free newspapers.
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $63 per night
At Pear Tree Inn Cape Girardeau Near the Medical Center, guests have access to an outdoor pool, free WiFi in public areas, and coffee in a common area. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a TV in a common area.
Candlewood Suites Cape Girardeau, an IHG Hotel

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
The price is $81 per night
At Candlewood Suites Cape Girardeau, an IHG Hotel, guests enjoy features like an indoor pool, a fitness center, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, free newspapers, and laundry facilities.
Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5
3265 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $69 per night
Guests staying at Auburn Place Hotel And Suites enjoy an indoor pool, a fitness center, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a meeting room, a 24-hour business center, and laundry facilities.
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $67 per night
Guests of Pear Tree Inn Cape Girardeau West enjoy a fitness center, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $99 per night
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a fitness center, and a spa tub. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
Guests of Quality Inn enjoy an outdoor pool, free WiFi in public areas, and a meeting room. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include a computer station and laundry facilities.
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
The price is $90 per night
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a fitness center, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a meeting room, a 24-hour business center, and a computer station.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Sikeston Casino Hotels

Don’t gamble on your room reservation on your next trip. Book a Sikeston hotel and casino and you’ll be in a prime spot for a memory-making getaway. You’ll get everything you need: cozy quarters for a good night’s sleep, excellent service and additional great perks like on-site restaurants and entertainment. Roll out of bed and be rolling at the tables in no time—now that’s how you make the most of a casino vacation in Sikeston.

You’re always a winner at Sikeston casino resorts
When you stay at resorts with casinos, your adventure begins even if you don’t hit the slots. Check in and head to your room, where you’ll enjoy amenities fit for a king. Complimentary bath products, plush towels and luxurious sheets are just the start. Book a room with a view and take in the sights of Sikeston from your balcony. That’s called living the high life.

You might not want to show your hand at the tables, but there are no secrets here on Orbitz. We can help you win big on your rate at Sikeston resort casino hotels, with prices ranging from $56 to $103. Book with us, and save your money for your epic casino trip.

Recent Casino Resorts & Hotels Reviews

    Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

    Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

    5/5 Excellent
    "This place was clean and very comfortable. The desk person was great. Jeremy was his name and made everything really easy. "…"
    A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
    Posted 2 days ago
    Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
    Pear Tree Inn Cape Girardeau Near the Medical Center

    Pear Tree Inn Cape Girardeau Near the Medical Center

    4/5 Good
    "Was relieved to get a room here after a nightmarish first night at the Townhouse Inn Jackson. There were multiple club sports tournaments going on in the area and every single hotel was booked up to 40 miles away. After our first night at the other place we were stuck with, the Pear Tree was a welcome change. Very soft clean bed and bedding, super sweet friendly staff and situated in the middle of restaurants and shopping, this is a nice budget hotel for the money. "…"
    A verified traveler stayed at Pear Tree Inn Cape Girardeau Near the Medical Center
    Posted 13 days ago
    Pear Tree Inn Cape Girardeau Near the Medical Center
    Pear Tree Inn Cape Girardeau West

    Pear Tree Inn Cape Girardeau West

    4/5 Good
    "Clean hotel. Small breakfast buffet. Comfortable beds and large bathroom. "…"
    A verified traveler stayed at Pear Tree Inn Cape Girardeau West
    Posted 1 month ago
    Pear Tree Inn Cape Girardeau West