Hotels with Casino in Sikeston, MO
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Featured Sikeston Casino Resorts & Hotels

Town House Inn Cape Giradreau
505 North Kingshighway Street, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
Town House Inn Cape Giradreau features free WiFi in public areas and a vending machine. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
Guests of Pear Tree Inn Cape Girardeau Near the Medical Center enjoy free WiFi in public areas, coffee in a common area, and express check-out. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a TV in a common area.
Pet friendly
Free WiFi

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Breakfast included
Pet friendly

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.
Pool
Breakfast included

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston hotels essential information
Accommodation | 261 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Town House Inn Cape Giradreau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau Near the Medical Center, Candlewood Suites Cape Girardeau by IHG, Pear Tree Inn Cape Girardeau West, Drury Inn & Suites Cape Girardeau, Quality Inn, Comfort Suites Jackson-Cape Girardeau |
Recent Casino Resorts & Hotels Reviews

Drury Inn & Suites Sikeston, MO
5/5 Excellent
Nice place to stop.
"Nice, clean hotel. It’s a very small town, but there is fast food nearby and close to the interstate. We made a quick one night stop but enjoyed the indoor/outdoor pool and indoor hot tub. The parking lot was very wel lit and the area felt safe. "
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 1 day ago
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