Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Hotel in Cape Girardeau with a full-service spa and free breakfast

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Indoor pool, open 8 AM to 11 PM, sun loungers
Exterior
Exterior
Premium bedding, down comforters, pillowtop beds, in-room safe

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Laundry
  • Housekeeping

Explore the area

Map
3253 William Street, Cape Girardeau, MO, 63701
  • Saint Francis Medical Center
    ‪6 min walk‬
  • Southeast Missouri State University
    ‪6 min drive‬
  • Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪7 min drive‬

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Room options

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

Standard Room, 1 Queen Bed

  • 400 sq ft
  • Sleeps 2
  • 1 Queen Bed

Suite, 2 Queen Beds, Accessible (Mobility)

  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

Suite, 2 Queen Beds

  • Sleeps 6
  • 2 Queen Beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

Standard Room

  • 400 sq ft
  • Sleeps 2
  • 1 King Bed

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

Suite, 1 King Bed, Accessible (Mobility)

  • Sleeps 2
  • 1 King Bed

Suite, 1 Bedroom (Feature)

  • Sleeps 2
  • 1 Queen Bed

About the neighborhood

Cape Girardeau

Located within a leisurely stroll of Saint Francis Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is within a few miles (5 km) of Saint Francis Healthcare System. This hotel has 102 rooms and welcomes guests with conveniences like free breakfast, a full-service spa, and an indoor pool.

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.4 miles
  • Cape Splash Family Aquatic Center - 5 min drive - 2.4 miles
  • Southeast Missouri State University - 6 min drive - 3.5 miles
  • Riverfront Bridge Park - 7 min drive - 4.0 miles
  • Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬6 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Panera Bread - ‬2 min walk
  • ‪Texas Roadhouse - ‬5 min walk
  • ‪O'Charley's Restaurant + Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries, and pillowtop beds with premium bedding and pillow menus ensure a restful night. Other amenities include sitting areas, microwaves, and coffee makers.
Recreational amenities at the hotel include an indoor pool and a fitness center.
Guests can indulge in a pampering treatment at the hotel's full-service spa.

Languages

English

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property doesn't allow pets

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
  • Check-in: 3:00 PM—-anytime
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a smoke detector.
  • Cashless payment methods are available for all transactions.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 11 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No cribs or infant beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG provides free cancellation on some room rates. For more details, review the cancellation policy on our site.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Jun 14, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Jul 13, 2025 start from $103.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to see close to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel is located in Cape Girardeau, close to Cape Splash Family Aquatic Center, Riverfront Bridge Park, and Isle Casino Cape Girardeau. You'll also find Shawnee National Forest and Mississippi River within a short drive.

Is there parking available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Is there a spa available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

There is a full-service spa at this available for guests to enjoy at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG include a casino at the property?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 11 PM.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG good for couples?

Couples staying at this hotel will appreciate amenities like a pillowtop mattress and free Internet access as well as an indoor pool.

Are there hot tubs at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there isn't a spa tub at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a restaurant that serves breakfast?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast though there is no restaurant.

Will Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

How close is the airport from Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

The closest major airport to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 6.1 mi away (10 minutes by car). Another top airport is Cairo, IL (CIR-Cairo Regional), which is around 25.5 mi away.

Can I book a room with a balcony at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there aren't any guestrooms with balconies at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 783 out of 1000 reviews
Rating 8 - Good. 152 out of 1000 reviews
Rating 6 - Okay. 34 out of 1000 reviews
Rating 4 - Poor. 13 out of 1000 reviews
Rating 2 - Terrible. 18 out of 1000 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Alicia

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Katie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Elizabeth

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff members were all very friendly and helpful. My room could not have been better.
Stayed 1 night in Mar 2025

8/10 Good

Lindsay

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Scott

Liked: Cleanliness, staff & service, property conditions & facilities
Love everything
Stayed 1 night in Mar 2025

10/10 Excellent

ken

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy walking distance to dining areas
Stayed 1 night in Mar 2025

10/10 Excellent

Brian

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lisa who was working in the breakfast area was very nice and helpful. Our room was very clean and comfortable.
Stayed 1 night in Mar 2025

10/10 Excellent

Pete

Traveled with partner
Liked: Staff & service, amenities, property conditions & facilities
Overall the property and rooms were clean and nice. Our only complaint was that the hallways and steps were filthy and needed vacuuming badly.
Stayed 1 night in Mar 2025

8/10 Good

Paul

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Neither good or bad - just standard.
Stayed 2 nights in Mar 2025

10/10 Excellent

Thomas

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very Good
Stayed 1 night in Mar 2025

10/10 Excellent

Brandon

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Tammy

Liked: Staff & service, property conditions & facilities
We enjoyed our stay and would recommend
Stayed 1 night in Mar 2025

6/10 Okay

Barbara

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Noisy

Kids should be put on the first floor!! Kiddo upstairs from us started running at 6.00 in the morning across the floor in the room above us!!
Stayed 1 night in Feb 2025

10/10 Excellent

Justin

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very good
Stayed 1 night in Feb 2025

10/10 Excellent

roger

Liked: Cleanliness, staff & service, property conditions & facilities
Easy access
Stayed 1 night in Mar 2025

10/10 Excellent

Cliff

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Feb 2025

10/10 Excellent

Nichole

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
So much around the hotel
Stayed 2 nights in Feb 2025

10/10 Excellent

Katherine

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Feb 2025

10/10 Excellent

Sara

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always a great stay!
Stayed 1 night in Feb 2025

10/10 Excellent

Kelci

Traveled with family and small children
Very clean
Stayed 2 nights in Feb 2025

8/10 Good

Brenda

Liked: Cleanliness, staff & service, property conditions & facilities
Easy highway access
Stayed 1 night in Feb 2025

10/10 Excellent

Steve

Stayed 2 nights in Feb 2025

10/10 Excellent

Savanna

Stayed 2 nights in Feb 2025

10/10 Excellent

SUSAN

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff! Everyone was so nice. They all seemed to love their job and were very helpful. The room was clean, quiet and spacious. We booked a room there again on a return trip.
Stayed 1 night in Jan 2025

10/10 Excellent

Carol

Liked: Cleanliness, staff & service, property conditions & facilities
The hotel was spotless. Our room was very spacious with nice furniture. Wonderful hot breakfast. Very competent front desk personnel. Highly recommend.
Stayed 1 night in Feb 2025