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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 is located 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within a 10-minute drive of Southeast Missouri State University. This 102-room hotel welcomes guests with conveniences like an indoor pool, free in-room WiFi, and free self parking. Isle Casino Cape Girardeau and Lazy L Safari Park are also a short drive away.


Start your day off with breakfast, available for a fee.


All 102 air-conditioned rooms feature sofa beds, microwaves, and refrigerators. Guests can enjoy satellite TV and stay connected with free WiFi and wired Internet. Other amenities include coffee makers, free newspapers, and free local calls.

Property features

Guests staying at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 enjoy an indoor pool, a fitness center, and free WiFi in public areas. Free parking is included with your stay. Helpful staff is there to provide a safe deposit box at the front desk, as well as offer insight about the area. Additional amenities include a meeting room, free newspapers, and laundry facilities.


  • Free WiFi and wired Internet in rooms and public areas
  • Free parking
  • Indoor pool
  • Fitness center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55

3253 William Street Cape Girardeau MO 63701

Hotel Amenities

Hotel Amenities

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 features an indoor pool and a fitness center. High-speed wired and wireless Internet access is complimentary. Event facilities measuring 120 square feet (11 square meters) include a meeting room. This Cape Girardeau hotel also offers complimentary newspapers in the lobby, laundry facilities, and a safe deposit box at the front desk. Complimentary self parking is available on site.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 is a smoke-free property.

  • Total number of rooms - 102 
  • Number of buildings/towers - 1 
  • Free WiFi 
  • Free wired high-speed Internet 
  • Conference space size (feet) - 120 
  • Conference space size (meters) - 11 
  • One meeting room 
  • Breakfast available (surcharge) 
  • Indoor pool 
  • Free newspapers in lobby 
  • Fitness facilities 
  • Porter/bellhop 
  • Number of floors - 4 
  • Elevator/lift 
  • Laundry facilities 
  • Safe-deposit box at front desk 
  • Free self parking 
  • Smoke-free property 

Family Friendly Amenities

  • Family Hotel  
  • Indoor pool  
  • Free Wi-Fi  
  • Rollaway/extra beds available  
  • Laundry facilities  
  • Sofa bed  
  • Refrigerator  
  • Microwave  


Available in all rooms: Free WiFi , Free wired high-speed Internet

Available in some public areas: Free WiFi , Free wired high-speed Internet


Free self parking

Room Amenities

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers 102 air-conditioned accommodations with complimentary newspapers and coffee/tea makers. Televisions come with premium satellite channels and pay movies. Guests can make use of the in-room refrigerators and microwaves.

This Cape Girardeau hotel provides complimentary wired and wireless high-speed Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include hair dryers and irons/ironing boards. Housekeeping is provided daily.

  • Connecting/adjoining rooms available 
  • Free WiFi 
  • Free wired high-speed Internet 
  • Sofa bed 
  • Rollaway/extra beds available 
  • Premium TV channels 
  • Pay movies 
  • Air conditioning 
  • Free newspaper 
  • In-room climate control (air conditioning) 
  • Phone 
  • Free local calls 
  • Refrigerator 
  • Coffee/tea maker 
  • Microwave 
  • Daily housekeeping 
  • Private bathroom 
  • Hair dryer 
  • Iron/ironing board 
  • Desk 
  • Satellite TV service 

Nearby Things to Do

Recreational amenities at the hotel include an indoor pool and a fitness center.


To make special requests for accessibility needs, please note them at check-out when you book your room.

  • Accessible bathroom 
  • Roll-in shower 
  • In-room accessibility 

Hotel Policies


Check-in time starts at 3 PM


Check-out time is 11 AM

Payment types


  • Pets not allowed

You need to know

Extra-person charges may apply and vary depending on property policy.

Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.

Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.

Hotel Name

  • Holiday Inn Express Cape Girardeau I-55
  • Holiday Inn Express Hotel Cape Girardeau I-55
  • Holiday Inn Hotel I-55

We should mention

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

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