Cape Girardeau County Vacation Rentals

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Top cities in Cape Girardeau County

Panorama of sand banks due to extreme low water conditions on Mississippi river in October 2023 in Missouri
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Cape Girardeau

Cape Girardeau

Cape Girardeau County Vacation Rentals

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau MO
At this vacation home, guests have access to a garden.
Little Blue Cottage on Spanish

Little Blue Cottage on Spanish

Cape Girardeau MO
$101 nightly
The price is $108 total per night
$108 total
Jun 19 - Jun 20
Total with taxes and fees
This vacation home is a smoke-free vacation home.
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cape Girardeau MO
Guests staying at this vacation home have access to laundry facilities, a water dispenser, and barbecue grills. This smoke-free vacation home also has a garden.
Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities

Cape girardeau MO
$291 nightly
The price is $306 total per night
$306 total
Jun 20 - Jun 21
Total with taxes and fees
At this cabin, guests have access to features like laundry facilities. This smoke-free cabin also has barbecue grills.
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

Cape Girardeau MO
$299 nightly
The price is $314 total per night
$314 total
Jun 21 - Jun 22
Total with taxes and fees
This cabin features a hot tub and a garden. This smoke-free cabin also has barbecue grills.
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau MO
$320 nightly
The price is $336 total per night
$336 total
Jul 14 - Jul 15
Total with taxes and fees
Guests of this vacation home enjoy features like an outdoor pool, a hot tub, and local meal delivery service. Additional amenities include barbecue grills and a garden.
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Jonesboro IL
This cabin features a hot tub and barbecue grills. This smoke-free cabin also has a garden.
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona IL
$184 nightly
The price is $194 total per night
$194 total
Jul 1 - Jul 2
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This vacation home also has barbecue grills.
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
$146 nightly
The price is $167 total per night
$167 total
Jun 25 - Jun 26
Total with taxes and fees
If you plan to drive, free parking is available.
Notting Hill Cottage

Notting Hill Cottage

Alto Pass IL
Guests staying at this vacation home enjoy a hot tub, laundry facilities, and barbecue grills.
Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite

Anna IL
$149 nightly
The price is $158 total per night
$158 total
Jun 21 - Jun 22
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities.
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
$187 nightly
The price is $198 total per night
$198 total
Jun 21 - Jun 22
Total with taxes and fees
At this cabin, guests have access to barbecue grills.
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
$187 nightly
The price is $198 total per night
$198 total
Jun 22 - Jun 23
Total with taxes and fees
This cabin features a hot tub and barbecue grills. This smoke-free cabin also has a garden.
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

Cobden IL
At this cabin, guests have access to barbecue grills.
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

Cobden IL
This cabin features a hot tub and barbecue grills.
Stones Throw from Giant City Park, Wineries, Hiking, Biking, Hunting and more.

Stones Throw from Giant City Park, Wineries, Hiking, Biking, Hunting and more.

Makanda IL
Guests staying at this cabin have access to barbecue grills and a garden.
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Makanda IL
$174 nightly
The price is $192 total per night
$192 total
Jun 29 - Jun 30
Total with taxes and fees
Guests staying at this cabin have access to a garden and barbecue grills.
Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

Makanda IL
Guests staying at this cabin enjoy a hot tub, laundry facilities, and barbecue grills. This golf cabin also has a garden.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Cape Girardeau County

    Drury Plaza Hotel Cape Girardeau Conference Center

    Drury Plaza Hotel Cape Girardeau Conference Center

    3351 Percy Drive Cape Girardeau MO
    $100 nightly
    The price is $113 total per night from Jun 28 to Jun 29
    $113 total
    Jun 28 - Jun 29
    Total with taxes and fees
    9.6/10 Exceptional! (1,003 reviews)
    The Riverview

    The Riverview

    777 Main St Cape Girardeau MO
    $131 nightly
    The price is $148 total per night from Jun 21 to Jun 22
    $148 total
    Jun 21 - Jun 22
    Total with taxes and fees
    9.4/10 Exceptional! (599 reviews)
    Candlewood Suites Cape Girardeau by IHG

    Candlewood Suites Cape Girardeau by IHG

    485 S Mount Auburn Rd Cape Girardeau MO
    $80 nightly
    The price is $96 total per night from Jun 21 to Jun 22
    $96 total
    Jun 21 - Jun 22
    Total with taxes and fees
    8/10 Very Good! (963 reviews)

Orbitz makes it easy to find vacation rentals in Cape Girardeau County 

🏠 What is the best price for a Cape Girardeau County vacation rental?


Cape Girardeau County rentals range between $96 and $336 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in Cape Girardeau County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next Cape Girardeau County getaway. Orbitz filters your search results so you can find the best Cape Girardeau County vacation rental for you. We have tons of options.


🏠 Are cancellations free on Cape Girardeau County vacation rentals with Orbitz?


You may be able to cancel or amend your Cape Girardeau County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in Cape Girardeau County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in Cape Girardeau County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in Cape Girardeau County?


When you book a Cape Girardeau County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in Cape Girardeau County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across Cape Girardeau County—with plenty of hidden gems. We also have plenty of inventory in Cape Girardeau County main cities and near popular attraction spots.


🏠 Why should I book my Cape Girardeau County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream Cape Girardeau County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


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