Book 5 Star Hotels in Cape Girardeau

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Oct 11 - Oct 12
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Check prices in Cape Girardeau for tonight, Oct 11 - Oct 12
Oct 12 - Oct 13
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Check prices in Cape Girardeau for tomorrow night, Oct 12 - Oct 13

Featured Cape Girardeau 5 Stars Hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
3.38 mi from city center
$90 nightly
The price is $102 total per night
$102 total
Oct 19 - Oct 20
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
0.51 mi from city center
$127 nightly
The price is $143 total per night
$143 total
Oct 19 - Oct 20
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and wedding services.
Parking included
Free WiFi
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
3.17 mi from city center
$70 nightly
The price is $79 total per night
$79 total
Oct 12 - Oct 13
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau Near the Medical Center enjoy free WiFi in public areas, coffee in a common area, and express check-out. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free hotel also has a TV in a common area.
Pet friendly
Free WiFi
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
3.45 mi from city center
$70 nightly
The price is $79 total per night
$79 total
Oct 12 - Oct 13
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
5.37 mi from city center
$98 nightly
The price is $111 total per night
$111 total
Oct 19 - Oct 20
Total with taxes and fees
Features of Tru By Hilton Cape Girardeau include an indoor pool and a gym. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready.
Pool
Breakfast included
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
0.24 mi from city center
$125 nightly
The price is $142 total per night
$142 total
Oct 26 - Oct 27
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown features a 24-hour gym, free WiFi in public areas, and meeting rooms. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a terrace.
Parking included
Free WiFi
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
4.03 mi from city center
$60 nightly
The price is $68 total per night
$68 total
Oct 23 - Oct 24
Total with taxes and fees
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.
Pool
Breakfast included
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
3.16 mi from city center
$74 nightly
The price is $89 total per night
$89 total
Nov 9 - Nov 10
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Free Cancellation
3.22 mi from city center
$95 nightly
The price is $107 total per night
$107 total
Oct 26 - Oct 27
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best 5 star hotels in Cape Girardeau

Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Cape Girardeau. After all, treating yourself to the finer things is what vacations are about. 

What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Cape Girardeau hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.

What amenities can I expect at a 5 star hotel?
Cape Girardeau 5 star hotels and resorts typically offer luxury amenities such as:

  • Gourmet restaurant
  • Full-service fitness center with pool
  • Luxury spa 
  • Welcome gifts upon arrival
  • Top-of-the-line beds and linens 
  • Designer personal care products
  • Premium cable, free Wi-Fi and device docking stations

How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Cape Girardeau with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place: 

  • Search hotels by price, ranging from $68 to $143
  • Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
  • Choose from 167 5 star hotels in Cape Girardeau!

Cape Girardeau hotels essential information

Accommodation
167 hotels
Lowest Price
$68
Highest Price
$143
Popular hotels
Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Pear Tree Inn Cape Girardeau Near the Medical Center, Pear Tree Inn Cape Girardeau West, Tru By Hilton Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown, Quality Inn, Candlewood Suites Cape Girardeau by IHG, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Recent Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

5/5 Excellent
"Everything was perfect, staff friendly and room was very clean. Breakfast was very good. Checkout went very smooth. Thank you!"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 17 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

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