Hotels in Sikeston

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  • May 26 - May 27
    Tonight
    Check prices in Sikeston for tonight, May 26 - May 27
  • May 27 - May 28
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  • May 27 - May 29
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    Check prices in Sikeston for this weekend, May 27 - May 29
  • Jun 3 - Jun 5
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    Check prices in Sikeston for next weekend, Jun 3 - Jun 5

Top Rated Sikeston Hotels

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.06 mi from city center
The price is $85 per night
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Pool
Free WiFi
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.11 mi from city center
The price is $108 per night
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Pool
Free WiFi
Travel Inn & Suites

Travel Inn & Suites

2.5 out of 5
100 Matthews Lane, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.07 mi from city center
The price is $64 per night
Guests of Travel Inn & Suites enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.
Free WiFi
Breakfast included
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.34 mi from city center
The price is $68 per night
Guests of Days Inn and Suites by Wyndham Sikeston enjoy features like a gym, free WiFi in public areas, and a library. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This hotel also has laundry facilities.
Free WiFi
Breakfast included
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.35 mi from city center
The price is $99 per night
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Free WiFi
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

2.5 out of 5
115 Hospitality Dr, Sikeston, MO, 63801
Free Cancellation
1.39 mi from city center
The price is $132 per night
Guests staying at Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Free WiFi
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
The price is $114 per night
Built in 2018, the brand new Hampton Inn Sikeston offers an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
2.87 mi from city center
The price is $59 per night
Super 8 by Wyndham Sikeston/Miner Area features free WiFi in public areas, a library, and laundry facilities. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Free WiFi
Breakfast included
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

2.5 out of 5
109 Matthews Ln, Sikeston, MO, 63801
Free Cancellation
Reserve now, pay when you stay
3.04 mi from city center
The price is $98 per night
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. Friendly staff can provide a safe deposit box at the front desk, and also offer advice about sightseeing. Additional amenities include a business center and laundry facilities.
Pool
Free WiFi
Country Yard Inn and Suite

Country Yard Inn and Suite

2 out of 5
110 S Interstate Dr, Sikeston, MO, 63801
3.44 mi from city center
At Country Yard Inn and Suite, guests have access to features like laundry facilities. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready.
Free WiFi
Parking included
Modern and Cozy Apartment with large windows and sunlight.

Modern and Cozy Apartment with large windows and sunlight.

Sikeston, MO
0.39 mi from city center
This apartment is a smoke-free apartment building.
Air conditioning
Pet friendly
Lambert’s Homestead. Very Cozy & Clean 5 bed home.

Lambert’s Homestead. Very Cozy & Clean 5 bed home.

Sikeston, MO
2.14 mi from city center
The price is $109 per night
Guests staying at this vacation home have access to an arcade/game room, a garden, and barbecue grills.
Kitchen
Air conditioning
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Sikeston

Pet Friendly Sikeston Hotels

    Auburn Place Hotel And Suites

    Auburn Place Hotel And Suites

    3265 William St, Cape Girardeau, MO, 63701
    The price is $79 per night from May 29 to May 30
    4.1/5 Very Good! (30 reviews)
    Auburn Place Hotel And Suites
    Drury Inn & Suites Sikeston, MO

    Drury Inn & Suites Sikeston, MO

    2608 East Malone Ave, Sikeston, MO, 63801
    The price is $108 per night from Jun 12 to Jun 13
    4.6/5 Exceptional! (34 reviews)
    Drury Inn & Suites Sikeston, MO
    Pear Tree Inn Sikeston

    Pear Tree Inn Sikeston

    2602 E Malone Avenue, Sikeston, MO, 63801
    The price is $85 per night from May 31 to Jun 1
    4.5/5 Wonderful! (19 reviews)
    Pear Tree Inn Sikeston

Where is a good place to stay in Sikeston?

What are the best hotels to stay with the kids in Sikeston?

Check out the 7 family-friendly hotels for your stay in Sikeston for your family's vacation. Super 8 by Wyndham Sikeston/Miner Area is a hotel offering free parking, free breakfast, and laundry facilities. You and your family can also consider Best Western Plus Sikeston, a hotel offering an indoor pool, free parking, and free full breakfast. Another option is Comfort Inn & Suites Sikeston I-55, a hotel offering an indoor pool, free parking, and laundry facilities.

What are some of the best hotels in central Sikeston?

These are some of our travelers' favorite hotels in central Sikeston:

You'll love Sikeston for its array of shops and popular restaurants. Close to central Sikeston, you'll find interesting places to visit like Central Park.

What are some favorite hotels close to Isle Casino Cape Girardeau?

Try your luck at this well-known casino, 3.6 mi from central Cape Girardeau. You'll find 9 hotels within a mile of Isle Casino Cape Girardeau and here are some of the top choices in the area:

Recent Reviews

  • Travel Inn & Suites

    Travel Inn & Suites

    4/5 Good
    "Refrigerator wasn’t working properly and the carpet was dirty but overall a nice stay"
    A verified traveler stayed at Travel Inn & Suites
    Posted 2 months ago
    Travel Inn & Suites
  • Drury Inn & Suites Sikeston, MO

    Drury Inn & Suites Sikeston, MO

    5/5 Excellent
    "Great stay. Clean."
    A verified traveler stayed at Drury Inn & Suites Sikeston, MO
    Posted 2 months ago
    Drury Inn & Suites Sikeston, MO
  • Days Inn and Suites by Wyndham Sikeston

    Days Inn and Suites by Wyndham Sikeston

    4/5 Good
    "The soap dispenser was empty in tub. Had to ask for butter for waffles. They keep it in freezer."
    A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
    Posted 4 months ago
    Days Inn and Suites by Wyndham Sikeston