Cheap flights from TRI to SAN (Tri-Cities Regional to San Diego Intl.)

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Cheap Flights from TRI to SAN starting at $379 One Way, $349 Round Trip

Prices starting at $349 for return flights and $379 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 7 - Tue, Oct 13
TRI
Tri-Cities
SAN
San Diego
$349 Roundtrip, found 22 hours ago
$349
Roundtrip
found 22 hours ago
Select Delta flight, departing Wed, Oct 7 from Tri-Cities to San Diego, returning Tue, Oct 13, priced at $349 found 22 hours ago
Tue, Jul 14 - Mon, Jul 20
TRI
Tri-Cities
SAN
San Diego
$357 Roundtrip, found 2 days ago
$357
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 14 from Tri-Cities to San Diego, returning Mon, Jul 20, priced at $357 found 2 days ago
Wed, Oct 7 - Tue, Oct 13
TRI
Tri-Cities
SAN
San Diego
$369 Roundtrip, found 22 hours ago
$369
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Oct 7 from Tri-Cities to San Diego, returning Tue, Oct 13, priced at $369 found 22 hours ago
Wed, Oct 7 - Tue, Oct 13
TRI
Tri-Cities
SAN
San Diego
$384 Roundtrip, found 22 hours ago
$384
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Oct 7 from Tri-Cities to San Diego, returning Tue, Oct 13, priced at $384 found 22 hours ago
Tue, Jul 14 - Mon, Jul 20
TRI
Tri-Cities
SAN
San Diego
$393 Roundtrip, found 2 days ago
$393
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 14 from Tri-Cities to San Diego, returning Mon, Jul 20, priced at $393 found 2 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$206 nightly
The price is $237 total per night from May 31 to Jun 1
$237 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,542 reviews)
"Our stay was amazing. We celebrated my wife’s graduation and it was truly unforgettable. Our girls loved the pool and we had the best time. We can’t wait to be back."

Reviewed on May 26, 2026

Sheraton San Diego Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$153 nightly
The price is $177 total per night from May 27 to May 28
$177 total
May 27 - May 28
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,118 reviews)
"Hotel is really nice, located in a good part of downtown. Public transit stops are nearby. I would say my only down is our fridge didn’t work. Other than that our stay was great!"

Reviewed on May 26, 2026

The Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from May 31 to Jun 1
$211 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,156 reviews)
"Just the 50 dollar parking a night charge"

Reviewed on May 26, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$153 nightly
The price is $177 total per night from May 27 to May 28
$177 total
May 27 - May 28
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,118 reviews)
"Hotel is really nice, located in a good part of downtown. Public transit stops are nearby. I would say my only down is our fridge didn’t work. Other than that our stay was great!"

Reviewed on May 26, 2026

The Sofia Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$276 nightly
The price is $320 total per night from Jun 14 to Jun 15
$320 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,819 reviews)
"Great place to stay I recommend it"

Reviewed on May 26, 2026

Manchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$248 nightly
The price is $285 total per night from May 31 to Jun 1
$285 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,612 reviews)
"Beautiful Vacation spot."

Reviewed on May 26, 2026

Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from May 31 to Jun 1
$211 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,156 reviews)
"Just the 50 dollar parking a night charge"

Reviewed on May 26, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$206 nightly
The price is $237 total per night from May 31 to Jun 1
$237 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,542 reviews)
"Our stay was amazing. We celebrated my wife’s graduation and it was truly unforgettable. Our girls loved the pool and we had the best time. We can’t wait to be back."

Reviewed on May 26, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$144 nightly
The price is $166 total per night from Jun 7 to Jun 8
$166 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,066 reviews)
"Breakfast was good and fresh! Clean room and the staff is excelent."

Reviewed on May 26, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$94 nightly
The price is $107 total per night from Jun 3 to Jun 4
$107 total
Jun 3 - Jun 4
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,413 reviews)
"Jesus is the man! Thu’s energy is super contagious! This is Tye Khuong lol! This is my second review within 6 months of travels yay for Maria as well she runs and operates the cleaning team so I gave her a small tip as a courtesy!!!"

Reviewed on May 26, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$62 nightly
The price is $71 total per night from May 27 to May 28
$71 total
May 27 - May 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,120 reviews)
"The air conditioner worked well. The room was clean. The pet area was covered with dog poop and there was a dead rat close by. Staff was friendly."

Reviewed on May 26, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$92 nightly
The price is $106 total per night from May 27 to May 28
$106 total
May 27 - May 28
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,711 reviews)
"The check-in time is quite late 4 pm but if you are lucky, they can check you in a little earlier. The swimming pool is nice and the water is slightly heated. The room was spacious and clean."

Reviewed on May 26, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$257 nightly
The price is $296 total per night from May 31 to Jun 1
$296 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,098 reviews)
"The staff was great. The beach access is wonderful. The two things I wish I had known about was our extremely out dated and dirty room. The carpet, smell and ripped sheets felt like i was staying at a motel 6 off a freeway. If you are to stay DO NOT get a room in the back. The low fence and short ..."

Reviewed on May 26, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$214 nightly
The price is $246 total per night from May 27 to May 28
$246 total
May 27 - May 28
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,377 reviews)
"We liked the safety and cleanliness of this facility at night we enjoyed the hot tub while watching the outdoor movie. We loved the area we took walks in the evenings while thwre and we enjoyed that the beach was so close."

Reviewed on May 26, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$283 nightly
The price is $325 total per night from Jun 4 to Jun 5
$325 total
Jun 4 - Jun 5
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,260 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"Great location, super nice staff and perfect room"

Reviewed on May 26, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TRI to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TRI Address & GPS
Address:
2525 Tennessee 75
Bristol, VA/Johnson City/Kingsport TN, 37617
United States
IATA Code:
TRI
Longitude:
-82.407852
Latitude:
36.481109
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

What is the shortest flight from TRI to San Diego Intl. Airport (SAN)?
Use the opportunity to unwind on the flight from Blountville to San Diego. The shortest flight time from Tri-Cities Airport to SAN is 6 hours and 20 minutes, which gives you loads of time to indulge in a tipple or get engrossed in a book.
How many hours flight from TRI to SAN?
From Tri-Cities Airport to SAN, you'll be in your seat for roughly 6 hours and 26 minutes. Settle back, order a glass of bubbly and take out your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Tri-Cities Airport to San Diego Intl. Airport (SAN)?
If you're hoping to book with an airline that flies direct from TRI to San Diego Intl. Airport (SAN), you won't have much luck. You'll have to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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