Cheap flights from TRI to SAN (Tri-Cities Regional to San Diego Intl.)

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Cheap Flights from TRI to SAN starting at $381 One Way, $359 Round Trip

Prices starting at $359 for return flights and $381 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 6 - Mon, Feb 8
TRI
Tri-Cities
SAN
San Diego
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Feb 6 from Tri-Cities to San Diego, returning Mon, Feb 8, priced at $359 found 4 days ago
Sat, Feb 6 - Mon, Feb 8
TRI
Tri-Cities
SAN
San Diego
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Feb 6 from Tri-Cities to San Diego, returning Mon, Feb 8, priced at $359 found 4 days ago
Fri, Oct 23 - Sat, Oct 31
TRI
Tri-Cities
SAN
San Diego
$364 Roundtrip, found 4 days ago
$364
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Oct 23 from Tri-Cities to San Diego, returning Sat, Oct 31, priced at $364 found 4 days ago
Sat, Feb 6 - Mon, Feb 8
TRI
Tri-Cities
SAN
San Diego
$394 Roundtrip, found 4 days ago
$394
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Feb 6 from Tri-Cities to San Diego, returning Mon, Feb 8, priced at $394 found 4 days ago
Sat, Feb 6 - Mon, Feb 8
TRI
Tri-Cities
SAN
San Diego
$429 Roundtrip, found 4 days ago
$429
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Feb 6 from Tri-Cities to San Diego, returning Mon, Feb 8, priced at $429 found 4 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
The price is $245 total per night from Sep 27 to Sep 28
$245 total
per night
Sep 27 - Sep 28
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (3,696 reviews)
"Beautiful resort."

Reviewed on Sep 13, 2026

Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is $211 total per night from Sep 20 to Sep 21
$211 total
per night
Sep 20 - Sep 21
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,319 reviews)
"The carpet is in a substandard condition, and there was a lack of transparency regarding the additional fees and parking charges during the reception process."

Reviewed on Sep 13, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is $137 total per night from Sep 20 to Sep 21
$137 total
per night
Sep 20 - Sep 21
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$119 nightly
The price is $137 total per night from Sep 20 to Sep 21
$137 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,902 reviews)
"We had a good stay thank you"

Reviewed on Sep 14, 2026

Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 20 to Sep 21
$97 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,910 reviews)
"A great quick place to catch some sleep"

Reviewed on Sep 14, 2026

Best Western Seven Seas
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,322 reviews)
"Great hotel to stay at… All staff are friendly and welcoming. most importantly for me and my family the accommodation we requested were met which means so much to us. We will definitely continue to stay at this hotel."

Reviewed on Sep 14, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is $211 total per night from Sep 20 to Sep 21
$211 total
per night
Sep 20 - Sep 21
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,319 reviews)
"The carpet is in a substandard condition, and there was a lack of transparency regarding the additional fees and parking charges during the reception process."

Reviewed on Sep 13, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
The price is $245 total per night from Sep 27 to Sep 28
$245 total
per night
Sep 27 - Sep 28
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (3,696 reviews)
"Beautiful resort."

Reviewed on Sep 13, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
The price is $166 total per night from Sep 23 to Sep 24
$166 total
per night
Sep 23 - Sep 24
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,087 reviews)
"Very accom"

Reviewed on Sep 13, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$75 nightly
The price is $86 total per night from Sep 20 to Sep 21
$86 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Sep 15 to Sep 16
$81 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,209 reviews)
"I will not stay here again. I don’t recommend it."

Reviewed on Sep 14, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$92 nightly
The price is $105 total per night from Oct 14 to Oct 15
$105 total
Oct 14 - Oct 15
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,753 reviews)
"Came to San Diego for a birthday weekend trip. I’ve stayed here a few times before. Friendly staff. Clean hotel rooms. A/C works perfectly! (Especially during the heatwave!)"

Reviewed on Sep 14, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from Oct 13 to Oct 14
$257 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$186 nightly
The price is $213 total per night from Sep 28 to Sep 29
$213 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,425 reviews)
"We were very disappointed in our stay. We didn’t receive housekeeping on one of our 3 day stay. We notified the front desk at approximately 4:00 pm and were told that they would send someone right out. When we returned for the evening the room was still unattended. Also the mattresses on the beds ..."

Reviewed on Sep 13, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$251 nightly
The price is $289 total per night from Oct 12 to Oct 13
$289 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,362 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"Staff was very nice. The room was very clean. Loved the pool."

Reviewed on Sep 14, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TRI to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TRI Address & GPS
Address:
2525 Tennessee 75
Bristol, VA/Johnson City/Kingsport TN, 37617
United States
IATA Code:
TRI
Longitude:
-82.407852
Latitude:
36.481109
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

What is the shortest flight from TRI to San Diego Intl. Airport (SAN)?
Use the opportunity to unwind on the flight from Blountville to San Diego. The shortest flight time from Tri-Cities Airport to SAN is 6 hours and 20 minutes, which gives you loads of time to indulge in a tipple or get engrossed in a book.
How many hours flight from TRI to SAN?
From Tri-Cities Airport to SAN, you'll be in your seat for roughly 6 hours and 26 minutes. Settle back, order a glass of bubbly and take out your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Tri-Cities Airport to San Diego Intl. Airport (SAN)?
If you're hoping to book with an airline that flies direct from TRI to San Diego Intl. Airport (SAN), you won't have much luck. You'll have to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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