Cheap flights from TPA to STL (Tampa Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from TPA to STL starting at $121 One Way, $225 Round Trip

Prices starting at $225 for return flights and $121 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 6 - Sat, Oct 10
TPA
Tampa
STL
St. Louis
$225 Roundtrip, found 16 hours ago
$225
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Oct 6 from Tampa to St. Louis, returning Sat, Oct 10, priced at $225 found 16 hours ago
Mon, Aug 17 - Wed, Aug 19
TPA
Tampa
STL
St. Louis
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Aug 17 from Tampa to St. Louis, returning Wed, Aug 19, priced at $244 found 2 days ago
Tue, Jul 7 - Tue, Jul 14
TPA
Tampa
STL
St. Louis
$246 Roundtrip, found 3 days ago
$246
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Jul 7 from Tampa to St. Louis, returning Tue, Jul 14, priced at $246 found 3 days ago
Tue, Oct 6 - Sat, Oct 10
TPA
Tampa
STL
St. Louis
$250 Roundtrip, found 16 hours ago
$250
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Oct 6 from Tampa to St. Louis, returning Sat, Oct 10, priced at $250 found 16 hours ago
Thu, Oct 15 - Tue, Oct 20
TPA
Tampa
STL
St. Louis
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Oct 15 from Tampa to St. Louis, returning Tue, Oct 20, priced at $250 found 1 day ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Jun 8 to Jun 9
$106 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,995 reviews)
"This place was a surprise, I needed a place for one night due to my last minute flight change. They had a shuttle which runs every 20 min which was so convenient. Rooms were very clean and breakfast was very good. Friendly staff and shuttle drivers made the entire stay pleasant"

Reviewed on May 28, 2026

Pear Tree Inn St. Louis Airport
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

3 out of 5
10490 Natural Bridge Rd St. Louis MO
$123 nightly
The price is $144 total per night from Jun 14 to Jun 15
$144 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,256 reviews)
"Property was very nice and the room was very comfortable and clean."

Reviewed on May 29, 2026

Drury Inn & Suites St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
$135 nightly
The price is $158 total per night from Jun 12 to Jun 13
$158 total
Jun 12 - Jun 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,081 reviews)
"Beautiful property and rooms. Very nice lobby with restaurant and bar. Onsite parking, but costs to park. Wonderful staff!"

Reviewed on May 25, 2026

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$144 nightly
The price is $169 total per night from May 31 to Jun 1
$169 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,058 reviews)
"Clean and very helpful staff"

Reviewed on May 28, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
$122 nightly
The price is $143 total per night from May 31 to Jun 1
$143 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,207 reviews)
"Enjoyed our stay. Room was nice, clean. No valet was a disappointment and the wait at one of the restaurants was insane for how many open tables were available."

Reviewed on May 28, 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
$98 nightly
The price is $114 total per night from Jun 1 to Jun 2
$114 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,307 reviews)
"I was told my reservation was canceled and could not check in but my card was still charged $100+ for room."

Reviewed on May 29, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$66 nightly
The price is $77 total per night from Jun 14 to Jun 15
$77 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,003 reviews)
"Smelled like mildew, hairs in my bed, stain on sheet, and dead bug in my sheets"

Reviewed on May 28, 2026

Quality Inn Saint Louis Airport
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$166 nightly
The price is $198 total per night from Jun 28 to Jun 29
$198 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8/10 Very Good! (1,000 reviews)
"So convenient to the airport and shuttle 14/7. Buffett breakfast was fabulous. Would stay again"

Reviewed on May 25, 2026

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$161 nightly
The price is $192 total per night from Jun 5 to Jun 6
$192 total
Jun 5 - Jun 6
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,000 reviews)
"Excellent breakfast and wait staff."

Reviewed on May 28, 2026

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$66 nightly
The price is $77 total per night from Jun 14 to Jun 15
$77 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,003 reviews)
"Smelled like mildew, hairs in my bed, stain on sheet, and dead bug in my sheets"

Reviewed on May 28, 2026

Quality Inn Saint Louis Airport
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$99 nightly
The price is $116 total per night from May 31 to Jun 1
$116 total
May 31 - Jun 1
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and Busch Stadium are located ...
5.6/10 (843 reviews)
"Hotel room i stayed had multiple issues that were not resolved. I was not told that the maintenance person was out.. finally moved to another room that has no cold water in shower."

Reviewed on May 13, 2026

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
6.6/10 (1,000 reviews)
"Definitely an older hotel. Overall the room was kinda dingy."

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...

Families like: Indoor pool, playground, game room, cribs

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$153 nightly
The price is $179 total per night from Jun 8 to Jun 9
$179 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,447 reviews)
"The hotel was super clean and nice staff! Their breakfast was the best I’ve ever had in my whole travels! They served afternoon snack which was a light dinner and was great"

Reviewed on May 29, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$122 nightly
The price is $143 total per night from Jun 3 to Jun 4
$143 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,972 reviews)
"My family had a wonderful stay."

Reviewed on May 29, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TPA to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from Tampa Intl. Airport (TPA) to St. Louis Lambert International Airport?
Southwest Airlines makes jetting from Tampa to St. Louis a snap. It offers direct flights from TPA to Lambert-St. Louis Intl. Airport (STL), so you won't have to bother with changing aircraft.
What is the shortest flight from TPA to St. Louis Lambert International Airport?
If you believe your vacation hours should be spent 'vacationing' rather than flying, you'll enjoy the journey from Tampa Airport to Lambert-St. Louis Intl. Airport (STL). It takes as little as 2 hours and 30 minutes.
How many hours flight from TPA to Lambert Field?
It takes an easy 2 hours and 33 minutes on average to travel from TPA to STL. Pull out that travel guide and circle the places you want to visit. It won't be long before you'll be seeing them in person.
What airlines have the most flights from Tampa Intl. Airport (TPA) to St. Louis Lambert International Airport?
Southwest Airlines has your ticket to an exciting vacation. This renowned carrier has 102 flights every month from Tampa to St. Louis.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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