Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

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Cheap Flights from ORD to DSM starting at $144 One Way, $280 Round Trip

Prices starting at $280 for return flights and $144 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Apr 20 - Tue, Apr 21
ORD
Chicago
DSM
Des Moines
$280 Roundtrip, found 5 days ago
$280
Roundtrip
found 5 days ago
Select United flight, departing Mon, Apr 20 from Chicago to Des Moines, returning Tue, Apr 21, priced at $280 found 5 days ago
Mon, Apr 20 - Tue, Apr 21
ORD
Chicago
DSM
Des Moines
$290 Roundtrip, found 5 days ago
$290
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Apr 20 from Chicago to Des Moines, returning Tue, Apr 21, priced at $290 found 5 days ago
Wed, May 6 - Mon, May 11
ORD
Chicago
DSM
Des Moines
$291 Roundtrip, found 6 days ago
$291
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, May 6 from Chicago to Des Moines, returning Mon, May 11, priced at $291 found 6 days ago
Mon, Apr 20 - Tue, Apr 21
ORD
Chicago
DSM
Des Moines
$299 Roundtrip, found 5 days ago
$299
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Apr 20 from Chicago to Des Moines, returning Tue, Apr 21, priced at $299 found 5 days ago
Wed, May 6 - Mon, May 11
ORD
Chicago
DSM
Des Moines
$301 Roundtrip, found 6 days ago
$301
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, May 6 from Chicago to Des Moines, returning Mon, May 11, priced at $301 found 6 days ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Mar 30 to Mar 31
$74 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,752 reviews)
We were placed in the only open room which for a light sleeper should never have been right behind the elevator. Bed in 221 had a divot in it and was uncomfortable.

Reviewed on Mar 23, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$114 nightly
The price is $128 total per night from Apr 19 to Apr 20
$128 total
Apr 19 - Apr 20
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Airport shuttle was fast and timely…on-site long-term parking was easy

Reviewed on Mar 21, 2026

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
$60 nightly
The price is $67 total per night from Mar 29 to Mar 30
$67 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,003 reviews)
The airport shuttle was nice. The rooms were mediocre beds comfy

Reviewed on Mar 22, 2026

AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$130 nightly
The price is $146 total per night from Apr 4 to Apr 5
$146 total
Apr 4 - Apr 5
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,092 reviews)
In my opinion the bathroom was the nicest of any hotel we have ever stayed in! The staff were welcoming and helpful. There is a parking garage behind the hotel that charged us $10.00 for our overnight stay. There is a skywalk that connects it the hotel. It was a little confusing, but that was probably ...

Reviewed on Mar 22, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$83 nightly
The price is $94 total per night from Mar 29 to Mar 30
$94 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,238 reviews)
Friendly staff, great breakfast, clean rooms, love the area around the hotel. My favorite place to stay in Des Moines.

Reviewed on Mar 23, 2026

Wildwood Lodge
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
$89 nightly
The price is $100 total per night from Mar 29 to Mar 30
$100 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,004 reviews)
Staff was wonderful and very helpful. Location very convenient to downtown.

Reviewed on Mar 23, 2026

Home2 Suites by Hilton Des Moines at Drake University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Mar 30 to Mar 31
$74 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,752 reviews)
We were placed in the only open room which for a light sleeper should never have been right behind the elevator. Bed in 221 had a divot in it and was uncomfortable.

Reviewed on Mar 23, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$63 nightly
The price is $70 total per night from Mar 30 to Mar 31
$70 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (1,005 reviews)
The hot tub doesn't work

Reviewed on Mar 22, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$114 nightly
The price is $128 total per night from Apr 19 to Apr 20
$128 total
Apr 19 - Apr 20
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Airport shuttle was fast and timely…on-site long-term parking was easy

Reviewed on Mar 21, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
The price is $61 total per night from Mar 24 to Mar 25
$61 total
per night
Mar 24 - Mar 25
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (782 reviews)
The bathroom door lock was broken. The front door was difficult to lock. The bathroom did not have hotel shampoo. On a good note, the room was clean and the bed was comfortable.

Reviewed on Mar 19, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
The price is $80 total per night from Apr 14 to Apr 15
$80 total
per night
Apr 14 - Apr 15
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (653 reviews)
The room was clean and the staff friendly. It is an old motel but was perfect for a quick stay while on the road as it is inexpensive.

Reviewed on Feb 21, 2026

Cozy Rest Motel
Quality Inn West Des Moines - Clive

Quality Inn West Des Moines - Clive

2 out of 5
1258 8th St West Des Moines IA
The price is $67 total per night from Apr 21 to Apr 22
$67 total
per night
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (39 reviews)
Very bad service! Hateful front desk staff. I would not recommend this hotel!!!!!

Reviewed on Mar 22, 2026

Quality Inn West Des Moines - Clive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$83 nightly
The price is $94 total per night from Mar 29 to Mar 30
$94 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,238 reviews)
Friendly staff, great breakfast, clean rooms, love the area around the hotel. My favorite place to stay in Des Moines.

Reviewed on Mar 23, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$80 nightly
The price is $89 total per night from Mar 24 to Mar 25
$89 total
Mar 24 - Mar 25
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (765 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
Not a great experience, though staff was great to work with problem solving. The room we got didn't have a pull-out sofa bed as advertised, and there were 6 of us! We asked for a roll away, none was found, but no one told us.We had to purchase a blow up mattress for sleeping. We had to ask for bedding ...

Reviewed on Mar 23, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$86 nightly
The price is $97 total per night from Apr 5 to Apr 6
$97 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,173 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Was clean and a nice place for family to stay

Reviewed on Mar 20, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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