$134 Cheap flight deals from Gainesville (MCO) to Des Moines (DSM)

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Airfares from $134 One Way, $255 Round Trip from Gainesville to Des Moines

Prices starting at $255 for return flights and $134 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 20 - Fri, Aug 22
MCO
Orlando
DSM
Des Moines
$255 Roundtrip, found 2 days ago
$255
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Wed, Aug 20 from Orlando to Des Moines, returning Fri, Aug 22, priced at $255 found 2 days ago
Thu, Sep 4 - Fri, Sep 5
MCO
Orlando
DSM
Des Moines
$261 Roundtrip, found 4 days ago
$261
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Orlando to Des Moines, returning Fri, Sep 5, priced at $261 found 4 days ago
Thu, Aug 21 - Fri, Aug 22
MCO
Orlando
DSM
Des Moines
$266 Roundtrip, found 2 days ago
$266
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Orlando to Des Moines, returning Fri, Aug 22, priced at $266 found 2 days ago
Thu, Sep 4 - Mon, Sep 8
MCO
Orlando
DSM
Des Moines
$267 Roundtrip, found 6 hours ago
$267
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Orlando to Des Moines, returning Mon, Sep 8, priced at $267 found 6 hours ago
Wed, Aug 20 - Sun, Aug 24
MCO
Orlando
DSM
Des Moines
$271 Roundtrip, found 2 days ago
$271
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Wed, Aug 20 from Orlando to Des Moines, returning Sun, Aug 24, priced at $271 found 2 days ago

Des Moines economy flight packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 West Des Moines, IA
2.0-star property

Motel 6 West Des Moines, IA

8/10 Very Good! (395 reviews)

Aug 7 - Aug 11

4 night stay

Orlando (MCO) to Des Moines (DSM)

American Airlines • Non-stop • Coach

Des Moines (DSM) to Orlando (MCO)

Frontier Airlines • Non-stop • Coach
per person
found 1 day ago
Reasonable rate and convenient. Hot water did not get hot just warm

Reviewed on May 29, 2025

Stoney Creek Hotel Des Moines - Johnston
2.5-star property

Stoney Creek Hotel Des Moines - Johnston

9/10 Wonderful! (1,727 reviews)

Aug 7 - Aug 11

4 night stay

Orlando (MCO) to Des Moines (DSM)

American Airlines • Non-stop • Coach

Des Moines (DSM) to Orlando (MCO)

Frontier Airlines • Non-stop • Coach
per person
found 1 day ago
The exterior looks good, but the interior is dated and many areas need updating. Main elevator was out of order, as was our closest ice maker and the washing machine. The mattress was well worn, but we did have plenty of pillows!The sink was partially plugged and drained slowly. Breakfast was the normal variety. We had no trouble getting extra towels from the desk. Its not a bad place to stay and it is kid/pet friendly.

Reviewed on Dec 28, 2024

Holiday Inn Downtown - Mercy Area by IHG
3.0-star property

Holiday Inn Downtown - Mercy Area by IHG

8/10 Very Good! (1,000 reviews)

Aug 7 - Aug 11

4 night stay

Orlando (MCO) to Des Moines (DSM)

American Airlines • Non-stop • Coach

Des Moines (DSM) to Orlando (MCO)

Frontier Airlines • Non-stop • Coach
per person
found 1 day ago
It is a decent location for us. The building itself is extremly outdated. The windows provide no sound barrier. The carpet and curtains have been around way to long. The bathroom was a decent size. Needs better placement of light switches and outlets.

Reviewed on Aug 22, 2023

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More About Flying To Des Moines from Gainesville

Route Information for Flights from Gainesville to Des Moines

Origin Airport IATA Code
MCO
Destination Airport IATA Code
DSM
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Gainesville to Des Moines

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Find Cheap Gainesville to Des Moines Flights

Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Gainesville to Des Moines. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.

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Discount Travel Planning Made Simple

You will have no problems finding budget flights from Gainesville to Des Moines on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.

Frequently asked questions

What is the shortest flight from Gainesville to Des Moines?
With the trip from Gainesville to Des Moines taking a minimum of 3 hours and 25 minutes, you'll have enough time to relax and enjoy the experience. Grab an in-flight wine and sink into your seat with an absorbing movie or novel.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.