
$134 Cheap flight deals from Gainesville (MCO) to Des Moines (DSM)
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Airfares from $134 One Way, $255 Round Trip from Gainesville to Des Moines
Prices starting at $255 for return flights and $134 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

Motel 6 West Des Moines, IA
Aug 7 - Aug 11
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on May 29, 2025

Stoney Creek Hotel Des Moines - Johnston
Aug 7 - Aug 11
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on Dec 28, 2024

Holiday Inn Downtown - Mercy Area by IHG
Aug 7 - Aug 11
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on Aug 22, 2023
More About Flying To Des Moines from Gainesville
Route Information for Flights from Gainesville to Des Moines
Origin Airport IATA Code | MCO |
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Destination Airport IATA Code | DSM |
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Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Gainesville to Des Moines
Orbitz is the best place to find guaranteed low prices on Gainesville to Des Moines flights. Because of our cutting-edge mobile tools and low fares on domestic and international flights, Orbitz is the best starting point for travelers.
Find Cheap Gainesville to Des Moines Flights
Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Gainesville to Des Moines. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.
Get Miles and Points for Your Flight
Simply enter your frequent flyer information while booking to get miles or points for qualifying Gainesville to Des Moines flights. This information can all be saved in your Orbitz account, which means it will not have to be entered each time you take advantage of a great air fare deal.
Flight Alerts Take Away the Stress
Orbitz does not want travelers to worry on their flights from Gainesville to Des Moines. We keep you updated on any flight changes for Gainesville to Des Moines flights with alerts sent directly to your email or a mobile device. These alerts can also be sent to friends and family.
Discount Travel Planning Made Simple
You will have no problems finding budget flights from Gainesville to Des Moines on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.
Frequently asked questions
- Flights to Des Moines
- Flights from Gainesville
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Flights to Des Moines
- Denver to Des Moines
- Phoenix to Des Moines
- Dallas to Des Moines
- Chicago to Des Moines
- New York to Des Moines
- Houston to Des Moines
- Orlando to Des Moines
- Las Vegas to Des Moines
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- Charlotte to Des Moines
- San Francisco to Des Moines
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- Beijing to Des Moines
- Montreal to Des Moines
- Barcelona to Des Moines
Flights from Gainesville
- Gainesville to Orlando
- Gainesville to Dallas
- Gainesville to Key West
- Gainesville to New York
- Gainesville to Houston
- Gainesville to Detroit
- Gainesville to Chicago
- Gainesville to Washington
- Gainesville to Newark
- Gainesville to Toronto
- Gainesville to Chattanooga
- Gainesville to Columbia
- Gainesville to Wilmington
- Gainesville to Columbia
- Gainesville to Rome
- Gainesville to Augusta
- Gainesville to Dothan
- Gainesville to Grand Junction
Des Moines Airports
- Flights to Waterloo
- Flights to Cedar Rapids
- Flights to Columbia
- Flights to Joplin
- Flights to Manhattan
- Flights to Kansas City
- Flights to Des Moines
- Flights to Sioux City
- Flights to Springfield
- Flights to Cedar Rapids Iowa City
- Flights to Hays
- Flights to Wichita
- Flights to Topeka
- Flights to Kansas City
- Flights to Branson
- Flights to Ames
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.