Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

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Cheap Flights from ORD to DSM starting at $121 One Way, $237 Round Trip

Prices starting at $237 for return flights and $121 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 15 - Tue, Oct 20
ORD
Chicago
DSM
Des Moines
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 15 from Chicago to Des Moines, returning Tue, Oct 20, priced at $237 found 1 day ago
Thu, Oct 15 - Tue, Oct 20
ORD
Chicago
DSM
Des Moines
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select United flight, departing Thu, Oct 15 from Chicago to Des Moines, returning Tue, Oct 20, priced at $237 found 1 day ago
Thu, Oct 15 - Tue, Oct 20
ORD
Chicago
DSM
Des Moines
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Select United flight, departing Thu, Oct 15 from Chicago to Des Moines, returning Tue, Oct 20, priced at $241 found 1 day ago
Tue, Oct 13 - Thu, Oct 15
ORD
Chicago
DSM
Des Moines
$249 Roundtrip, found 2 days ago
$249
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 13 from Chicago to Des Moines, returning Thu, Oct 15, priced at $249 found 2 days ago
Thu, Oct 15 - Tue, Oct 20
ORD
Chicago
DSM
Des Moines
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 15 from Chicago to Des Moines, returning Tue, Oct 20, priced at $251 found 1 day ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$70 nightly
The price is $79 total per night from Sep 30 to Oct 1
$79 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,810 reviews)
"The location was close to the airport which was a plus. Check in took a while and there was no one in front of me. I chose a room with a king sized bed. The room was next to the elevator- very noisy. The hotel was less than half full so not sure why our king room was one next to the elevator. I'm ..."

Reviewed on Sep 20, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$110 nightly
The price is $123 total per night from Oct 18 to Oct 19
$123 total
Oct 18 - Oct 19
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,009 reviews)
"Overall the room was great and the bed and pillows were super comfortable, but the room smelt like something burned in there. The free breakfast was just ok, and one the morning from desk clerk was not overly pleasant and the cleaning crew just didn't speak to us."

Reviewed on Sep 20, 2026

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

3 out of 5
1920 Hackley Ave Des Moines IA
$68 nightly
The price is $76 total per night from Sep 23 to Sep 24
$76 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$126 nightly
The price is $141 total per night from Oct 11 to Oct 12
$141 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,328 reviews)
"Loved the hotel and the restaurants. Will stay here again"

Reviewed on Sep 20, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
$109 nightly
The price is $122 total per night from Sep 22 to Sep 23
$122 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,907 reviews)
"The room was clean when we got there. There were amenities offered including a pool and free breakfast. Staff was nice and check-in and out were very quick and efficient."

Reviewed on Sep 20, 2026

Stoney Creek Hotel Des Moines - Johnston
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$107 nightly
The price is $120 total per night from Sep 22 to Sep 23
$120 total
Sep 22 - Sep 23
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Wildwood Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$70 nightly
The price is $79 total per night from Sep 30 to Oct 1
$79 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,810 reviews)
"The location was close to the airport which was a plus. Check in took a while and there was no one in front of me. I chose a room with a king sized bed. The room was next to the elevator- very noisy. The hotel was less than half full so not sure why our king room was one next to the elevator. I'm ..."

Reviewed on Sep 20, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$64 nightly
The price is $71 total per night from Oct 11 to Oct 12
$71 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (1,004 reviews)
"I really enjoyed staying there. They took me over to the airport twice as I left something in the room and they search for it for me."

Reviewed on Sep 18, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$110 nightly
The price is $123 total per night from Oct 18 to Oct 19
$123 total
Oct 18 - Oct 19
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,009 reviews)
"Overall the room was great and the bed and pillows were super comfortable, but the room smelt like something burned in there. The free breakfast was just ok, and one the morning from desk clerk was not overly pleasant and the cleaning crew just didn't speak to us."

Reviewed on Sep 20, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$59 nightly
The price is $67 total per night from Sep 22 to Sep 23
$67 total
Sep 22 - Sep 23
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$75 nightly
The price is $84 total per night from Oct 20 to Oct 21
$84 total
Oct 20 - Oct 21
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Cozy Rest Motel
Quality Inn West Des Moines - Clive

Quality Inn West Des Moines - Clive

2 out of 5
1258 8th St West Des Moines IA
$68 nightly
The price is $76 total per night from Sep 27 to Sep 28
$76 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (145 reviews)
"The coffee pot was missing parts, the hair dryer did not work. We told the front desk and nothing was done about it. We went to the front desk and asked for more towels. This was a 2 bed and 3 night stay. She gave us 2 towels. No wash cloths. No conditioner in the bottle they have in the shower."

Reviewed on Sep 21, 2026

Quality Inn West Des Moines - Clive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$107 nightly
The price is $120 total per night from Sep 22 to Sep 23
$120 total
Sep 22 - Sep 23
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$71 nightly
The price is $80 total per night from Sep 27 to Sep 28
$80 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.8/10 (1,070 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
"Horrible"

Reviewed on Sep 21, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$92 nightly
The price is $103 total per night from Oct 18 to Oct 19
$103 total
Oct 18 - Oct 19
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,204 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
"Pool wasn't very warm and was dirty. Room smelled like wet dog. Bed was lumpy."

Reviewed on Sep 19, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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