Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

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Cheap Flights from ORD to DSM starting at $108 One Way, $280 Round Trip

Prices starting at $280 for return flights and $108 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 26 - Mon, Jun 29
ORD
Chicago
DSM
Des Moines
$280 Roundtrip, found 2 days ago
$280
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jun 26 from Chicago to Des Moines, returning Mon, Jun 29, priced at $280 found 2 days ago
Thu, May 14 - Fri, May 15
ORD
Chicago
DSM
Des Moines
$281 Roundtrip, found 5 days ago
$281
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, May 14 from Chicago to Des Moines, returning Fri, May 15, priced at $281 found 5 days ago
Fri, Jun 26 - Mon, Jun 29
ORD
Chicago
DSM
Des Moines
$290 Roundtrip, found 2 days ago
$290
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jun 26 from Chicago to Des Moines, returning Mon, Jun 29, priced at $290 found 2 days ago
Thu, May 14 - Fri, May 15
ORD
Chicago
DSM
Des Moines
$291 Roundtrip, found 5 days ago
$291
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, May 14 from Chicago to Des Moines, returning Fri, May 15, priced at $291 found 5 days ago
Thu, May 14 - Fri, May 15
ORD
Chicago
DSM
Des Moines
$304 Roundtrip, found 5 days ago
$304
Roundtrip
found 5 days ago
Select United flight, departing Thu, May 14 from Chicago to Des Moines, returning Fri, May 15, priced at $304 found 5 days ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$68 nightly
The price is $76 total per night from Apr 26 to Apr 27
$76 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,776 reviews)
The second night of stay my room card did not work I had to go back to the desk to get re-programmed. After checking out I realized the next day I had left my phone charger. I stopped back by & they had to look in 3 different locations all to come up empty. They said call back maybe on housekeeping ...

Reviewed on Apr 20, 2026

Days Inn & Suites by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
$70 nightly
The price is $78 total per night from Apr 26 to Apr 27
$78 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,003 reviews)
Worked for what we needed.

Reviewed on Apr 18, 2026

AmericInn by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$121 nightly
The price is $135 total per night from Apr 26 to Apr 27
$135 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,006 reviews)
Breakfast was excellent and staff were the best!

Reviewed on Apr 18, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$144 nightly
The price is $161 total per night from Apr 26 to Apr 27
$161 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,126 reviews)
A jewel nestled in downtown Des Moines. All of the staff was friendly and accommodating. Will definitely stay here again.

Reviewed on Apr 21, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$68 nightly
The price is $76 total per night from Apr 26 to Apr 27
$76 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,776 reviews)
The second night of stay my room card did not work I had to go back to the desk to get re-programmed. After checking out I realized the next day I had left my phone charger. I stopped back by & they had to look in 3 different locations all to come up empty. They said call back maybe on housekeeping ...

Reviewed on Apr 20, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$51 nightly
The price is $57 total per night from Apr 23 to Apr 24
$57 total
Apr 23 - Apr 24
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (821 reviews)
Great as always

Reviewed on Apr 20, 2026

Motel 6 West Des Moines, IA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$68 nightly
The price is $76 total per night from Apr 26 to Apr 27
$76 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,776 reviews)
The second night of stay my room card did not work I had to go back to the desk to get re-programmed. After checking out I realized the next day I had left my phone charger. I stopped back by & they had to look in 3 different locations all to come up empty. They said call back maybe on housekeeping ...

Reviewed on Apr 20, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$63 nightly
The price is $71 total per night from Apr 30 to May 1
$71 total
Apr 30 - May 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (1,011 reviews)
They denied me a room saying I was on a "Do not rent to this person" list, which they could not tell me the reason I was on any list to begin with. Very offended

Reviewed on Apr 20, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$121 nightly
The price is $135 total per night from Apr 26 to Apr 27
$135 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,006 reviews)
Breakfast was excellent and staff were the best!

Reviewed on Apr 18, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$51 nightly
The price is $57 total per night from Apr 23 to Apr 24
$57 total
Apr 23 - Apr 24
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (821 reviews)
Great as always

Reviewed on Apr 20, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$68 nightly
The price is $76 total per night from Apr 23 to Apr 24
$76 total
Apr 23 - Apr 24
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (654 reviews)
6yy

Reviewed on Mar 29, 2026

Cozy Rest Motel
Quality Inn West Des Moines - Clive

Quality Inn West Des Moines - Clive

2 out of 5
1258 8th St West Des Moines IA
$64 nightly
The price is $72 total per night from Apr 26 to Apr 27
$72 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (52 reviews)
Gas station and restaurant very close by

Reviewed on Apr 17, 2026

Quality Inn West Des Moines - Clive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$104 nightly
The price is $116 total per night from Apr 26 to Apr 27
$116 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,246 reviews)
We were disappointed that the hot tub was out of order during our stay. After a long day of wrestling the hot tub would have felt great on tired sore muscles and help keep them from cramping the following day during an another long day of wrestling. We also said that our room didn’t need to be turned ...

Reviewed on Apr 20, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$82 nightly
The price is $92 total per night from Apr 26 to Apr 27
$92 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (798 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
U over charged my card not Expedia but the hotel it’s self

Reviewed on Apr 20, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$92 nightly
The price is $103 total per night from Apr 27 to Apr 28
$103 total
Apr 27 - Apr 28
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,166 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Didn’t have breakfast. It’s a trucker stop. Supposedly non smokers room. We couldn’t sleep from cigarette smell. Manager told us they are fully refunded charge back to Expedia.

Reviewed on Apr 20, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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