Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from ORD to DSM starting at $135 One Way, $243 Round Trip

Prices starting at $243 for return flights and $135 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 22 - Wed, May 6
ORD
Chicago
DSM
Des Moines
$243 Roundtrip, found 6 days ago
$243
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Apr 22 from Chicago to Des Moines, returning Wed, May 6, priced at $243 found 6 days ago
Wed, Apr 22 - Wed, May 6
ORD
Chicago
DSM
Des Moines
$253 Roundtrip, found 6 days ago
$253
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Apr 22 from Chicago to Des Moines, returning Wed, May 6, priced at $253 found 6 days ago
Wed, Apr 22 - Wed, May 6
ORD
Chicago
DSM
Des Moines
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Apr 22 from Chicago to Des Moines, returning Wed, May 6, priced at $259 found 6 days ago
Wed, Apr 22 - Wed, May 6
ORD
Chicago
DSM
Des Moines
$278 Roundtrip, found 6 days ago
$278
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Apr 22 from Chicago to Des Moines, returning Wed, May 6, priced at $278 found 6 days ago
Wed, Apr 22 - Wed, May 6
ORD
Chicago
DSM
Des Moines
$280 Roundtrip, found 6 days ago
$280
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Apr 22 from Chicago to Des Moines, returning Wed, May 6, priced at $280 found 6 days ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Apr 13 to Apr 14
$74 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,765 reviews)
Left to early for breakfast - shuttle was great

Reviewed on Apr 3, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$122 nightly
The price is $137 total per night from Apr 19 to Apr 20
$137 total
Apr 19 - Apr 20
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Friendly front desk staff. The property, although clean was definitely dated and shows signs of wear. We would probably chose a different place near the airport next time.

Reviewed on Apr 5, 2026

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
$74 nightly
The price is $83 total per night from Apr 6 to Apr 7
$83 total
Apr 6 - Apr 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,003 reviews)
We had to leave before they served breakfast and the young lady at checkout, Jaya, said they would have muffins, bagels and granola bars to grab on the way out. They did not and the individual at the front desk said she had no idea why Jaya would say that🙁and that the owner would not allow it.

Reviewed on Mar 30, 2026

AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$144 nightly
The price is $161 total per night from Apr 19 to Apr 20
$161 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,108 reviews)
Staff, vallet, and room service was amazing!

Reviewed on Apr 1, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
$98 nightly
The price is $109 total per night from Apr 12 to Apr 13
$109 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,009 reviews)
The state was very convenient very clean, very quick and efficient

Reviewed on Apr 4, 2026

Home2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$87 nightly
The price is $98 total per night from May 3 to May 4
$98 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,239 reviews)
Breakfast was good and had more choices than most, hot tub and pool area looked really nice, but we didn't use. Room was clean and had everything needed would definitely stay again

Reviewed on Apr 4, 2026

Wildwood Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Apr 13 to Apr 14
$74 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,765 reviews)
Left to early for breakfast - shuttle was great

Reviewed on Apr 3, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$63 nightly
The price is $71 total per night from Apr 15 to Apr 16
$71 total
Apr 15 - Apr 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (1,001 reviews)
Nice

Reviewed on Apr 2, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$122 nightly
The price is $137 total per night from Apr 19 to Apr 20
$137 total
Apr 19 - Apr 20
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Friendly front desk staff. The property, although clean was definitely dated and shows signs of wear. We would probably chose a different place near the airport next time.

Reviewed on Apr 5, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$42 nightly
The price is $47 total per night from Apr 21 to Apr 22
$47 total
Apr 21 - Apr 22
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (795 reviews)
Nothing fancy but very clean and friendly staff.Would highly recommend 👌

Reviewed on Apr 2, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$69 nightly
The price is $77 total per night from Apr 12 to Apr 13
$77 total
Apr 12 - Apr 13
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (654 reviews)
6yy

Reviewed on Mar 29, 2026

Cozy Rest Motel
Quality Inn West Des Moines - Clive

Quality Inn West Des Moines - Clive

2 out of 5
1258 8th St West Des Moines IA
$53 nightly
The price is $60 total per night from Apr 8 to Apr 9
$60 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (44 reviews)
Very clean smelled fresh and clean. Beds and pillows were great and I’m picky. Pool was great and breakfast was delicious. We will definitely stay again.

Reviewed on Apr 3, 2026

Quality Inn West Des Moines - Clive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$87 nightly
The price is $98 total per night from May 3 to May 4
$98 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,239 reviews)
Breakfast was good and had more choices than most, hot tub and pool area looked really nice, but we didn't use. Room was clean and had everything needed would definitely stay again

Reviewed on Apr 4, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$76 nightly
The price is $85 total per night from Apr 6 to Apr 7
$85 total
Apr 6 - Apr 7
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (780 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
Okay stay. Kids were happy. Tv and internet never worked properly.

Reviewed on Apr 5, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$87 nightly
The price is $98 total per night from Apr 6 to Apr 7
$98 total
Apr 6 - Apr 7
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,166 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
This was our first trip to Des Moines and we are extremely impressed with this hotel! We are a family of eight and we reserved two one-bedroom suites for two nights for under $350. Exceptional value! Pros: -Rooms, and whole hotel, were very clean. -Excellent amenities with a shop, arcade, rec room ...

Reviewed on Apr 2, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore