Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

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Cheap Flights from ORD to DSM starting at $80 One Way, $161 Round Trip

Prices starting at $161 for return flights and $80 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 3 - Sun, Apr 5
ORD
Chicago
DSM
Des Moines
$161 Roundtrip, found 7 hours ago
$161
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Apr 3 from Chicago to Des Moines, returning Sun, Apr 5, priced at $161 found 7 hours ago
Fri, Apr 3 - Sun, Apr 5
ORD
Chicago
DSM
Des Moines
$169 Roundtrip, found 7 hours ago
$169
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Apr 3 from Chicago to Des Moines, returning Sun, Apr 5, priced at $169 found 7 hours ago
Thu, Apr 2 - Sun, Apr 5
ORD
Chicago
DSM
Des Moines
$182 Roundtrip, found 22 hours ago
$182
Roundtrip
found 22 hours ago
Select Delta flight, departing Thu, Apr 2 from Chicago to Des Moines, returning Sun, Apr 5, priced at $182 found 22 hours ago
Thu, Apr 2 - Sun, Apr 5
ORD
Chicago
DSM
Des Moines
$192 Roundtrip, found 22 hours ago
$192
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Thu, Apr 2 from Chicago to Des Moines, returning Sun, Apr 5, priced at $192 found 22 hours ago
Thu, Apr 2 - Sun, Apr 5
ORD
Chicago
DSM
Des Moines
$194 Roundtrip, found 22 hours ago
$194
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Thu, Apr 2 from Chicago to Des Moines, returning Sun, Apr 5, priced at $194 found 22 hours ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
The price is $76 total per night from Feb 25 to Feb 26
$76 total
per night
Feb 25 - Feb 26
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,757 reviews)
The staff was very accommodating. However, the dirty disguss in the ice bucket lid kept me from having any desire to get ice or drink water from the establishment.

Reviewed on Feb 19, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
The price is $126 total per night from Mar 2 to Mar 3
$126 total
per night
Mar 2 - Mar 3
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Room was great and the staff was very helpful

Reviewed on Feb 19, 2026

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
The price is $68 total per night from Feb 23 to Feb 24
$68 total
per night
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,003 reviews)
Room was clean and spacious. Front desk person in the evening to check in was very nice and helpful but the front desk person in the morning was not at all friendly. A smile with a sincere good morning goes a long way.

Reviewed on Feb 17, 2026

AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
The price is $161 total per night from Feb 22 to Feb 23
$161 total
per night
Feb 22 - Feb 23
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,083 reviews)
Comfortable beds, clean, the most well dressed and courteous staff. I love the character this hotel has. It’s gorgeous.

Reviewed on Feb 16, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
The price is $83 total per night from Feb 22 to Feb 23
$83 total
per night
Feb 22 - Feb 23
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (725 reviews)
For

Reviewed on Feb 17, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2 out of 5
7625 Office Plaza Dr N West Des Moines IA
The price is $89 total per night from Feb 22 to Feb 23
$89 total
per night
Feb 22 - Feb 23
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (984 reviews)
Hotel was accomodating and welcoming...3 or 4 staff changes and still courteous. Definitely will be staying there again in the future!!

Reviewed on Feb 19, 2026

Sonesta Simply Suites Des Moines
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
The price is $76 total per night from Feb 25 to Feb 26
$76 total
per night
Feb 25 - Feb 26
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,757 reviews)
The staff was very accommodating. However, the dirty disguss in the ice bucket lid kept me from having any desire to get ice or drink water from the establishment.

Reviewed on Feb 19, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
The price is $69 total per night from Mar 22 to Mar 23
$69 total
per night
Mar 22 - Mar 23
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (1,000 reviews)
Clean hotel. Clean rooms and friendly staff. I booked it the last minute. Checked all my boxes for this hotel.

Reviewed on Feb 17, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
The price is $126 total per night from Mar 2 to Mar 3
$126 total
per night
Mar 2 - Mar 3
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Room was great and the staff was very helpful

Reviewed on Feb 19, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$46 nightly
The price is $51 total per night from Feb 22 to Feb 23
$51 total
Feb 22 - Feb 23
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (756 reviews)
Great staff. Love to see the same gentleman check us in during the day. So welcoming and professional. Motel 6 is a GEM.

Reviewed on Jan 31, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$70 nightly
The price is $79 total per night from Feb 20 to Feb 21
$79 total
Feb 20 - Feb 21
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Cozy Rest Motel
Quality Inn

Quality Inn

2 out of 5
1258 8th St West Des Moines IA
$52 nightly
The price is $59 total per night from Feb 22 to Feb 23
$59 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (26 reviews)
That gal at the front desk was very helpful and friendly!

Reviewed on Feb 19, 2026

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$78 nightly
The price is $88 total per night from Feb 22 to Feb 23
$88 total
Feb 22 - Feb 23
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,228 reviews)
Jenn was amazing!!! She was so easy to talk yo and answer all my questions. The hot tub was perfect- hot & it bubbled!! I have had a hard time finding hotels with the hot tubs that jets work and are actually hot and not pool temps! Breakfast was good variety of food as well. Pretty wuiet hotel and ...

Reviewed on Feb 17, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$74 nightly
The price is $83 total per night from Feb 22 to Feb 23
$83 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (725 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
For

Reviewed on Feb 17, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$84 nightly
The price is $94 total per night from Feb 25 to Feb 26
$94 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,177 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Excellent. Clean and practical and comfortable. No complaints.

Reviewed on Feb 16, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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