Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from ORD to DSM starting at $119 One Way, $243 Round Trip
Prices starting at $243 for return flights and $119 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
ORD
Chicago
DSM
Des Moines
$243 Roundtrip, found 4 days ago
$243
Roundtrip
found 4 days ago
ORD
Chicago
DSM
Des Moines
$243 Roundtrip, found 4 days ago
$243
Roundtrip
found 4 days ago
ORD
Chicago
DSM
Des Moines
$253 Roundtrip, found 4 days ago
$253
Roundtrip
found 4 days ago
ORD
Chicago
DSM
Des Moines
$263 Roundtrip, found 4 days ago
$263
Roundtrip
found 4 days ago
ORD
Chicago
DSM
Des Moines
$279 Roundtrip, found 4 days ago
$279
Roundtrip
found 4 days ago
Hotel Ideas near Des Moines Intl.
Airport Hotels near Des Moines Intl.
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
$75 nightly
The price is $84 total per night from May 10 to May 11
$84 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,774 reviews)
Their breakfast was so delicious and fresh kept! Highly recommend this place every time you visit Des Moines!
Reviewed on May 2, 2026
AmericInn by Wyndham Des Moines Airport
1920 Hackley Ave Des Moines IA
$70 nightly
The price is $78 total per night from May 4 to May 5
$78 total
May 4 - May 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,001 reviews)
Good parking. Good staff
Reviewed on May 2, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
$122 nightly
The price is $137 total per night from May 10 to May 11
$137 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
Just OK for Hampton
Reviewed on Apr 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
$130 nightly
The price is $146 total per night from May 24 to May 25
$146 total
May 24 - May 25
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,127 reviews)
The hotel is beautiful and I had the best night sleep.
Reviewed on Apr 25, 2026
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
$59 nightly
The price is $67 total per night from May 6 to May 7
$67 total
May 6 - May 7
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (842 reviews)
Very clean Close to interstate and couldn't hear the traffic. Close to the casino and restaurants. Flying J staff are super friendly. Love that it is pet friendly and no charge or having to show proof of esa or service animal
Reviewed on May 2, 2026
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
$75 nightly
The price is $84 total per night from May 10 to May 11
$84 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,774 reviews)
Their breakfast was so delicious and fresh kept! Highly recommend this place every time you visit Des Moines!
Reviewed on May 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Des Moines Hotels With Airport Transportation
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
$75 nightly
The price is $84 total per night from May 10 to May 11
$84 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,774 reviews)
Their breakfast was so delicious and fresh kept! Highly recommend this place every time you visit Des Moines!
Reviewed on May 2, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
$69 nightly
The price is $77 total per night from May 25 to May 26
$77 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (1,005 reviews)
Never changed the sheets in 4 nights.
Reviewed on May 1, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
$122 nightly
The price is $137 total per night from May 10 to May 11
$137 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
Just OK for Hampton
Reviewed on Apr 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Des Moines Hotels
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
$59 nightly
The price is $67 total per night from May 6 to May 7
$67 total
May 6 - May 7
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (842 reviews)
Very clean Close to interstate and couldn't hear the traffic. Close to the casino and restaurants. Flying J staff are super friendly. Love that it is pet friendly and no charge or having to show proof of esa or service animal
Reviewed on May 2, 2026
Cozy Rest Motel
2316 Southeast 14th Street Des Moines IA
$67 nightly
The price is $75 total per night from May 17 to May 18
$75 total
May 17 - May 18
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (656 reviews)
The room was very nicely remodeled but very BASIC....the concierge Dennis was available 24/7 & provided cups, bottled water & kleenex upon our request & delivered them to our room. The bed was very comfortable. There was no remote with the TV so we had to use the buttons on the TV itself. All in ...
Reviewed on Apr 27, 2026
Quality Inn West Des Moines - Clive
1258 8th St West Des Moines IA
$57 nightly
The price is $64 total per night from Jun 1 to Jun 2
$64 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (57 reviews)
Checked in after a long time of driving, my bed didn’t even have a blanket on it and it had a dirty sheet. The pillowcases were clearly reused. I asked the front desk to get this rectified and she wasn’t sympathetic at all. Just OK we’ll get it fixed when we get it fixed and I was like well. I need ...
Reviewed on Apr 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Des Moines
Wildwood Lodge
11431 Forest Ave Clive IA
$99 nightly
The price is $111 total per night from May 10 to May 11
$111 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,240 reviews)
It was a great hotel for the price and for a last minute booking! Just down the road from our sports complex!
Reviewed on May 1, 2026
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
$79 nightly
The price is $89 total per night from May 5 to May 6
$89 total
May 5 - May 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (803 reviews)
Families like: Kids pool, waterpark, game room, cribs
Travelers say...
Pool was cold and bar owner was drunk the whole time
Reviewed on Apr 28, 2026
Baymont by Wyndham Des Moines Airport
6221 Willow Creek Ave Des Moines IA
$93 nightly
The price is $104 total per night from May 10 to May 11
$104 total
May 10 - May 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,160 reviews)
Families like: Game room, cribs, rollaway beds, games and toys
Travelers say...
Clean, great staff, good breakfast!
Reviewed on Apr 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
ORD to DSM Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
- Great Travel Ideas
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
Other Flights from O'Hare Intl. Airport (ORD)
Other Flights to Des Moines Intl. Airport (DSM)
- Chicago Executive Airport (PWK)
- Midway Intl. Airport (MDW)
- Dupage Airport (DPA)
- Kenosha Regional Airport (ENW)
- Greater Rockford Airport (RFD)
- General Mitchell Intl. Airport (MKE)
- Waukesha County Airport (UES)
- South Bend Intl. Airport (SBN)
- Dane County Regional Airport (MSN)
- Goshen Municipal Airport (GSH)
Top Trending
Flights
- ORD to TPA
- MCO to ORD
- RSW to ORD
- ORD to CUN
- ORD to BOS
- ORD to DFW
- ORD to ATL
- ORD to PHX
- ORD to FLL
- LAX to ORD
- SNA to ORD
- DCA to ORD
- LGA to ORD
- SFO to ORD
- ORD to DCA
- ORD to RSW
- ORD to LGA
- ORD to LAS
- ORD to LHR
- ORD to SEA
- ORD to SNA
- EWR to ORD
- ORD to MIA
- ORD to LAX
- BDL to ORD
- ORD to MCO
- ORD to SFO
- ORD to FCA
- DFW to ORD
- ORD to VIE
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
More to Explore
- Flights from Honolulu to Des Moines
- Flights from Jackson to Des Moines
- Flights from Atlanta to Des Moines
- Flights from Austin to Des Moines
- Flights from Baltimore to Des Moines
- Flights from Boston to Des Moines
- Flights from Calgary to Des Moines
- Flights from Charlotte to Des Moines
- Flights from Chicago to Des Moines
- Flights from Cincinnati to Des Moines
- Flights from Cleveland to Des Moines
- Flights from Columbus to Des Moines
- Flights from Dallas to Des Moines
- Flights from Denver to Des Moines
- Flights from Detroit to Des Moines
- Flights from Houston to Des Moines
- Flights from Indianapolis to Des Moines
- Flights from Kansas City to Des Moines
- Flights from Las Vegas to Des Moines
- Flights from Los Angeles to Des Moines
- Flights from Memphis to Des Moines
- Flights from Miami to Des Moines
- Flights from Minneapolis - St. Paul to Des Moines
- Flights from Nairobi to Des Moines
- Flights from Nashville to Des Moines
- Flights from New Orleans to Des Moines
- Flights from New York to Des Moines
- Flights from Orlando to Des Moines
- Flights from Philadelphia to Des Moines
- Flights from Phoenix to Des Moines
- Flights from Portland to Des Moines
- Flights from Raleigh to Des Moines
- Flights from Salt Lake City to Des Moines
- Flights from San Antonio to Des Moines
- Flights from San Francisco to Des Moines
- Flights from Seattle to Des Moines
- Flights from St. Louis to Des Moines
- Flights from Toronto to Des Moines
- Flights from Vancouver to Des Moines
- Flights from Washington to Des Moines
- Flights from Charleston to Des Moines
- Flights from Hartford to Des Moines
- Flights from Providence to Des Moines
- Flights from Sacramento to Des Moines
- Flights from Maui to Des Moines
- Flights from Mason City to Des Moines
- Flights from Omaha to Des Moines
- Flights from Amarillo to Des Moines
- Flights from Pittsburgh to Des Moines
- Flights from Fort Lauderdale to Des Moines
- Flights from Newark to Des Moines
- Flights from Richmond to Des Moines
- Flights from Oakland to Des Moines
- Flights from Syracuse to Des Moines
- Flights from Toledo to Des Moines
- Flights from Tulsa to Des Moines
- Flights from Pensacola to Des Moines
- Flights from South Bend to Des Moines
- Flights from Champaign to Des Moines
- Flights from Manchester to Des Moines
- Flights from Milwaukee to Des Moines
- Flights from Albuquerque to Des Moines
- Flights from Buffalo to Des Moines
- Flights from Reno to Des Moines
- Flights from Medford to Des Moines
- Flights from Madison to Des Moines
- Flights from Fort Myers to Des Moines
- Flights from Little Rock to Des Moines
- Flights from Norfolk - Virginia Beach to Des Moines
- Flights from Harrisburg - Hershey to Des Moines
- Flights from Spokane to Des Moines
- Flights from Springfield to Des Moines
- Flights from Rochester to Des Moines
- Flights from Greensboro to Des Moines
- Flights from Oklahoma City to Des Moines
- Flights from Dayton to Des Moines
- Flights from Knoxville to Des Moines
- Flights from Cedar Rapids - Iowa City to Des Moines
- Flights from Birmingham to Des Moines
- Flights from Huntsville to Des Moines
- Flights from Tucson to Des Moines
- Flights from Fresno to Des Moines
- Flights from Colorado Springs to Des Moines
- Flights from Tampa to Des Moines
- Flights from Jacksonville to Des Moines
- Flights from Boise to Des Moines
- Flights from Fort Wayne to Des Moines
- Flights from Louisville to Des Moines
- Flights from Lexington to Des Moines
- Flights from Grand Rapids to Des Moines
- Flights from Savannah to Des Moines
- Flights from Gainesville to Des Moines
- Flights from Tallahassee to Des Moines
- Flights from Wichita to Des Moines
- Flights from Bismarck to Des Moines
- Flights from Rapid City to Des Moines
- Flights from Sioux Falls to Des Moines
- Flights from Lubbock to Des Moines
- Flights from Winnipeg to Des Moines
- Flights from Chattanooga to Des Moines