Cheap flights from ORD to DSM (O'Hare Intl. to Des Moines Intl.)

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Cheap Flights from ORD to DSM starting at $79 One Way, $177 Round Trip

Prices starting at $177 for return flights and $79 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 17 - Tue, Mar 31
ORD
Chicago
DSM
Des Moines
$177 Roundtrip, found 4 days ago
$177
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Mar 17 from Chicago to Des Moines, returning Tue, Mar 31, priced at $177 found 4 days ago
Tue, Apr 28 - Tue, May 12
ORD
Chicago
DSM
Des Moines
$177 Roundtrip, found 6 days ago
$177
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Apr 28 from Chicago to Des Moines, returning Tue, May 12, priced at $177 found 6 days ago
Wed, Mar 11 - Tue, Mar 24
ORD
Chicago
DSM
Des Moines
$180 Roundtrip, found 4 days ago
$180
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Mar 11 from Chicago to Des Moines, returning Tue, Mar 24, priced at $180 found 4 days ago
Wed, Apr 1 - Tue, Apr 7
ORD
Chicago
DSM
Des Moines
$182 Roundtrip, found 1 day ago
$182
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 1 from Chicago to Des Moines, returning Tue, Apr 7, priced at $182 found 1 day ago
Sat, Apr 4 - Tue, Apr 7
ORD
Chicago
DSM
Des Moines
$184 Roundtrip, found 1 day ago
$184
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 4 from Chicago to Des Moines, returning Tue, Apr 7, priced at $184 found 1 day ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$65 nightly
The price is $73 total per night from Feb 15 to Feb 16
$73 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,738 reviews)
clean room pleasant staff. nothing fancy. airport runs 24/7 on the half-hours

Reviewed on Feb 1, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $123 total per night from Feb 8 to Feb 9
$123 total
Feb 8 - Feb 9
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Great room/breakfast!

Reviewed on Feb 1, 2026

Hampton Inn Des Moines-Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$61 nightly
The price is $68 total per night from Feb 15 to Feb 16
$68 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
Room was great

Reviewed on Jan 22, 2026

Quality Inn & Suites Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$134 nightly
The price is $151 total per night from Feb 25 to Feb 26
$151 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,083 reviews)
Amazing is not the word for this place! Staff was amazing! Totally excited our expectations

Reviewed on Jan 26, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
$89 nightly
The price is $100 total per night from Feb 8 to Feb 9
$100 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,008 reviews)
Room and hotel was very clean, staff were friendly, would definitely stay again!

Reviewed on Jan 31, 2026

Home2 Suites by Hilton Des Moines at Drake University
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$65 nightly
The price is $73 total per night from Feb 15 to Feb 16
$73 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,738 reviews)
clean room pleasant staff. nothing fancy. airport runs 24/7 on the half-hours

Reviewed on Feb 1, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$65 nightly
The price is $73 total per night from Feb 15 to Feb 16
$73 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,738 reviews)
clean room pleasant staff. nothing fancy. airport runs 24/7 on the half-hours

Reviewed on Feb 1, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$61 nightly
The price is $68 total per night from Feb 15 to Feb 16
$68 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
Room was great

Reviewed on Jan 22, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $123 total per night from Feb 8 to Feb 9
$123 total
Feb 8 - Feb 9
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Great room/breakfast!

Reviewed on Feb 1, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$45 nightly
The price is $51 total per night from Feb 27 to Feb 28
$51 total
Feb 27 - Feb 28
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (743 reviews)
Great staff. Love to see the same gentleman check us in during the day. So welcoming and professional. Motel 6 is a GEM.

Reviewed on Jan 31, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$70 nightly
The price is $79 total per night from Feb 10 to Feb 11
$79 total
Feb 10 - Feb 11
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (651 reviews)
This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out.

Reviewed on Sep 25, 2025

Cozy Rest Motel
Quality Inn

Quality Inn

2 out of 5
1258 8th St West Des Moines IA
$51 nightly
The price is $57 total per night from Feb 8 to Feb 9
$57 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (21 reviews)
Staff was very helpful and courteous. Second time staying there. Would recommend to everyone!

Reviewed on Jan 23, 2026

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$87 nightly
The price is $98 total per night from Feb 8 to Feb 9
$98 total
Feb 8 - Feb 9
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,216 reviews)
The safe was above and beyond! They were so welcoming and friendly. The whole hotel it’s self was beautiful and very spotless and clean.. We loved it there differently give it a 10/10

Reviewed on Jan 30, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$70 nightly
The price is $78 total per night from Feb 8 to Feb 9
$78 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (706 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
Room a little dirty

Reviewed on Jan 22, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$80 nightly
The price is $90 total per night from Feb 5 to Feb 6
$90 total
Feb 5 - Feb 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,178 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Nice and clean

Reviewed on Jan 30, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from ORD to Des Moines Intl. Airport (DSM)?
You'll be pleased to hear that you can fly straight from O'Hare Intl. Airport (ORD) to Des Moines Intl. Airport (DSM). Direct flights can be booked with multiple companies, including United Airlines and American Airlines.
What is the shortest flight from O'Hare Intl. Airport (ORD) to DSM?
If you're of the opinion that your vacation hours should be spent 'vacationing' instead of flying, you'll enjoy the ride from ORD to DSM. It's a wonderfully short 1 hour and 24 minutes.
How many hours flight from O'Hare Intl. Airport (ORD) to DSM?
It takes just 1 hour and 32 minutes on average to fly from ORD to DSM. Whip out your guide book and start circling all the special places you want to visit. It won't be long before you'll be seeing them for yourself.
What airlines have the most flights from O'Hare Intl. Airport (ORD) to DSM?
Going on vacation is one of life's greatest pleasures, but how you get to your destination should be just as enjoyable. Look into booking your flight from O'Hare Airport to DSM with American Airlines (AA). One of the most popular airlines, it offers 97 flights on this route each month. Alternatively, secure your favorite seat with United Airlines (UA). You'll have 121 monthly flights between Chicago and Des Moines to choose from with this carrier.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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