$49 Cheap flight deals from Gainesville (MCO) to Columbia (JEF)

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This Weekend's Flight Deals from Gainesville to Columbia

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 10 - Fri, May 15
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$121 Roundtrip, found 3 days ago
$121
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, May 10 from Orlando Intl. to Lambert-St. Louis Intl., returning Fri, May 15, priced at $121 found 3 days ago
Sun, May 10 - Sun, May 17
MCO
Orlando Intl.
MCI
Kansas City Intl.
$586 Roundtrip, found 16 hours ago
$586
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Sun, May 10 from Orlando Intl. to Kansas City Intl., returning Sun, May 17, priced at $586 found 16 hours ago
Sat, May 9 - Sun, May 10
JAX
Jacksonville Intl.
STL
Lambert-St. Louis Intl.
$666 Roundtrip, found 2 days ago
$666
Roundtrip
found 2 days ago
Select United flight, departing Sat, May 9 from Jacksonville Intl. to Lambert-St. Louis Intl., returning Sun, May 10, priced at $666 found 2 days ago

Airfares from $49 One Way, $98 Round Trip from Gainesville to Columbia

Prices starting at $98 for return flights and $49 for one-way flights to Columbia were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jun 4 - Mon, Jun 8
MCO
Orlando
STL
St. Louis
$98 Roundtrip, found 15 hours ago
$98
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Thu, Jun 4 from Orlando to St. Louis, returning Mon, Jun 8, priced at $98 found 15 hours ago
Wed, May 27 - Wed, Jun 3
MCO
Orlando
MCI
Kansas City
$165 Roundtrip, found 4 days ago
$165
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Wed, May 27 from Orlando to Kansas City, returning Wed, Jun 3, priced at $165 found 4 days ago
Tue, Jun 2 - Wed, Jun 3
MCO
Orlando
STL
St. Louis
$219 Roundtrip, found 4 days ago
$219
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 2 from Orlando to St. Louis, returning Wed, Jun 3, priced at $219 found 4 days ago
Thu, Jun 4 - Tue, Jun 9
MCO
Orlando
STL
St. Louis
$224 Roundtrip, found 1 day ago
$224
Roundtrip
found 1 day ago
Select United flight, departing Thu, Jun 4 from Orlando to St. Louis, returning Tue, Jun 9, priced at $224 found 1 day ago
Tue, Sep 8 - Tue, Sep 15
JAX
Jacksonville
STL
St. Louis
$275 Roundtrip, found 2 days ago
$275
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Sep 8 from Jacksonville to St. Louis, returning Tue, Sep 15, priced at $275 found 2 days ago

Columbia economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9.2/10 Wonderful! (1,625 reviews)

Jun 14 - Jun 17

3 night stay

Orlando (MCO) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Orlando (MCO)

Frontier Airlines • Coach
Price was $800, price is now $576 per person
$576
per person
found 23 hours ago
Hotel was clean but honestly, outdated. Staff was great. The continental breakfast was fine. Biggest issue was the shower. There was next to no water pressure no matter the time of day. The mattress also felt cheap. I’m not a picky person and overall, I would stay again. Just maybe not in an upgraded room. I don’t feel like it was worth it.

Reviewed on Feb 24, 2026

Alhonna Resort LLC
3.0-star property

Alhonna Resort LLC

8.8/10 Excellent! (264 reviews)

Jun 19 - Jun 23

4 night stay

Orlando (MCO) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $1,053, price is now $720 per person
$720
per person
found 10 hours ago
Internet Wi-Fi needs upgraded.

Reviewed on Jul 17, 2024

Hilton Pennywell St. Louis at the Arch
4.0-star property

Hilton Pennywell St. Louis at the Arch

8.8/10 Excellent! (1,034 reviews)

Jun 24 - Jun 29

5 night stay

Orlando (MCO) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Orlando (MCO)

Frontier Airlines • Coach
Save 100% on your flight
Price was $1,009, price is now $724 per person
$724
per person
found 12 hours ago
Beautiful hotel. Friendly and helpful staff. Everything you would hope for

Reviewed on Apr 19, 2026

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More About Flying To Columbia from Gainesville

Route Information for Flights from Gainesville to Columbia

Origin Airport IATA Code
MCO
Destination Airport IATA Code
JEF
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Gainesville to Columbia

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Frequently asked questions

Are there non-stop flights from Gainesville to Columbia?
Yes, if you're cruising from MCO to Lambert Field, you'll only have one flight number to keep in mind. There are 3 airlines with nonstop services to pick from. Here are a few of the best:

  • Southwest Airlines
  • Spirit Airlines
  • Frontier Airlines

What is the shortest flight from Gainesville to Columbia?
It can take as little as 2 hours and 34 minutes to get from Jacksonville, FL (JAX-Jacksonville Intl.) to Lambert Field. Relax and enjoy the journey, because you'll be coming in to land before you know it.
What airlines fly from Gainesville to Columbia most frequently?
Southwest Airlines (WN) operates 130 flights every month between Orlando, FL (MCO-Orlando Intl.) to STL. Your next great adventure is just a few clicks away. Alternatively, book your favorite aisle (or window) seat with Spirit Airlines (NK). You'll have 30 monthly flights between Gainesville and Columbia to choose from with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.