Cheap flights from MSP to SDF (Minneapolis - St. Paul Intl. to Louisville Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MSP to SDF starting at $154 One Way, $308 Round Trip

Prices starting at $308 for return flights and $154 for one-way flights to Louisville Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Nov 16 - Tue, Nov 17
MSP
Minneapolis
SDF
Louisville
$308 Roundtrip, just found
$308
Roundtrip
just found
Select Southwest Airlines flight, departing Mon, Nov 16 from Minneapolis to Louisville, returning Tue, Nov 17, priced at $308 just found
Mon, Nov 16 - Tue, Nov 17
MSP
Minneapolis
SDF
Louisville
$313 Roundtrip, just found
$313
Roundtrip
just found
Select Southwest Airlines flight, departing Mon, Nov 16 from Minneapolis to Louisville, returning Tue, Nov 17, priced at $313 just found
Mon, Nov 16 - Tue, Nov 17
MSP
Minneapolis
SDF
Louisville
$355 Roundtrip, just found
$355
Roundtrip
just found
Select Southwest Airlines flight, departing Mon, Nov 16 from Minneapolis to Louisville, returning Tue, Nov 17, priced at $355 just found
Mon, Nov 16 - Tue, Nov 17
MSP
Minneapolis
SDF
Louisville
$360 Roundtrip, just found
$360
Roundtrip
just found
Select Southwest Airlines flight, departing Mon, Nov 16 from Minneapolis to Louisville, returning Tue, Nov 17, priced at $360 just found
Thu, Dec 3 - Tue, Dec 8
MSP
Minneapolis
SDF
Louisville
$361 Roundtrip, just found
$361
Roundtrip
just found
Select Southwest Airlines flight, departing Thu, Dec 3 from Minneapolis to Louisville, returning Tue, Dec 8, priced at $361 just found

Hotel Ideas near Louisville Intl.

Airport Hotels near Louisville Intl.

Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
$101 nightly
The price is $119 total per night from Oct 25 to Oct 26
$119 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,875 reviews)
"Very nice stay was there with large group and was nice. Only complaint was food in restaurant could’ve been better"

Reviewed on Oct 6, 2026

Crowne Plaza Louisville Airport Expo Ctr by IHG
Tru by Hilton Louisville Airport

Tru by Hilton Louisville Airport

2.5 out of 5
810 Phillips Lane Louisville KY
$86 nightly
The price is $101 total per night from Oct 13 to Oct 14
$101 total
Oct 13 - Oct 14
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"✨✨✨"

Reviewed on Oct 3, 2026

Tru by Hilton Louisville Airport
Springhill Suites by Marriott Louisville Airport

Springhill Suites by Marriott Louisville Airport

3 out of 5
820 Phillips Lane Louisville KY
$88 nightly
The price is $104 total per night from Oct 25 to Oct 26
$104 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,004 reviews)
"N/A"

Reviewed on Oct 4, 2026

Springhill Suites by Marriott Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Louisville

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$145 nightly
The price is $171 total per night from Oct 25 to Oct 26
$171 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
Galt House Hotel Trademark Collection by Wyndham
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
$152 nightly
The price is $179 total per night from Oct 28 to Oct 29
$179 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,342 reviews)
"Incredible hotel. Gorgeous historic building, wonderful staff and outstanding food. Highly recommend."

Reviewed on Oct 6, 2026

The Brown Hotel
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
$76 nightly
The price is $85 total per night from Oct 12 to Oct 13
$85 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (3,429 reviews)
"For some reason, all of the hallways and everywhere we went inside the hotel smelt like a skunk. Don’t know if there was an actual skunk there or if it’s all weed smell."

Reviewed on Oct 4, 2026

Radisson Hotel Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Louisville Hotels With Airport Transportation

The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
$152 nightly
The price is $179 total per night from Oct 28 to Oct 29
$179 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,342 reviews)
"Incredible hotel. Gorgeous historic building, wonderful staff and outstanding food. Highly recommend."

Reviewed on Oct 6, 2026

The Brown Hotel
Holiday Inn Express Louisville Airport Expo Center by IHG

Holiday Inn Express Louisville Airport Expo Center by IHG

2.5 out of 5
1921 Bishop Ln Louisville KY
$88 nightly
The price is $104 total per night from Oct 14 to Oct 15
$104 total
Oct 14 - Oct 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Express Louisville Airport Expo Center by IHG
Sleep Inn Louisville Airport

Sleep Inn Louisville Airport

2 out of 5
709 Phillips Lane Louisville KY
$64 nightly
The price is $74 total per night from Oct 27 to Oct 28
$74 total
Oct 27 - Oct 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,000 reviews)
"Clean and well kept. Just needed a place to sleep for the night and they served that well."

Reviewed on Oct 5, 2026

Sleep Inn Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Louisville Hotels

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

2 out of 5
401 S 2nd St Louisville KY
$63 nightly
The price is $74 total per night from Oct 26 to Oct 27
$74 total
Oct 26 - Oct 27
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7/10 Good! (1,003 reviews)
"It was a lower cost, and nice place to stay in Louisville for a short trip."

Reviewed on Oct 5, 2026

Econo Lodge Louisville Downtown
Red Roof Inn Louisville Fair and Expo

Red Roof Inn Louisville Fair and Expo

2 out of 5
3322 Red Roof Inn Pl Louisville KY
$60 nightly
The price is $71 total per night from Oct 12 to Oct 13
$71 total
Oct 12 - Oct 13
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,001 reviews)
"Was super convenient for me and my dogs in our situation. I'm greatfull"

Reviewed on Oct 3, 2026

Red Roof Inn Louisville Fair and Expo
Super 8 by Wyndham Louisville Airport

Super 8 by Wyndham Louisville Airport

2.5 out of 5
4800 Preston Hwy Louisville KY
$56 nightly
The price is $66 total per night from Oct 11 to Oct 12
$66 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff ...
4.8/10 (1,002 reviews)
"The bathroom toilet was dirty ,carpet needed vacuumed"

Reviewed on Oct 4, 2026

Super 8 by Wyndham Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Louisville

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North

3 out of 5
9597 Brownsboro Road Louisville KY
$100 nightly
The price is $118 total per night from Oct 13 to Oct 14
$118 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,063 reviews)
"Staff was great. Property a little dated."

Reviewed on Oct 5, 2026

Drury Inn & Suites Louisville North
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$145 nightly
The price is $171 total per night from Oct 25 to Oct 26
$171 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
Galt House Hotel Trademark Collection by Wyndham
Country Inn & Suites by Radisson, Louisville South, KY

Country Inn & Suites by Radisson, Louisville South, KY

2 out of 5
400 Paroquet Springs Drive Shepherdsville KY
$77 nightly
The price is $85 total per night from Oct 27 to Oct 28
$85 total
Oct 27 - Oct 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Shepherdsville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,003 reviews)
"Rooms were clean, staff was friendly. The breakfast was disappointing"

Reviewed on Oct 5, 2026

Country Inn & Suites by Radisson, Louisville South, KY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MSP to SDF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from MSP to Louisville Intl. Airport (SDF)?
Passengers can jet from Minneapolis - St. Paul Intl. Airport (MSP) to SDF with Delta Air Lines, the only carrier that offers nonstop services on this route.
What is the shortest flight from Minneapolis - St. Paul Intl. Airport (MSP) to Louisville Muhammad Ali Intl. Airport?
Jetting from MSP to Louisville Intl. Airport (SDF) takes at least 4 hours and 46 minutes. Treat yourself to a wine and watch a flick or two — it's the ideal opportunity to sit back and unwind.
How many hours flight from Wold–Chamberlain Field to Louisville Muhammad Ali Intl. Airport?
On average, it takes just 4 hours and 53 minutes to travel from Wold–Chamberlain Field to Louisville Intl. Airport (SDF). With such a short amount of time in the sky, you'll need to save that binge-viewing for a longer trip.
What airlines have the most flights from Minneapolis - St. Paul Intl. Airport (MSP) to Louisville Intl. Airport (SDF)?
Delta Air Lines has your ticket to an unforgettable vacation. This renowned airline offers 126 monthly flights from Minneapolis - St. Paul to Louisville.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore