Cheap flights from LYS to SAN (Saint-Exupery to San Diego Intl.)

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Cheap Flights from LYS to SAN starting at $554 One Way, $864 Round Trip

Prices starting at $864 for return flights and $554 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 21 - Mon, Dec 7
LYS
Lyon
SAN
San Diego
$864 Roundtrip, found 15 hours ago
$864
Roundtrip
found 15 hours ago
Select Iberia flight, departing Sat, Nov 21 from Lyon to San Diego, returning Mon, Dec 7, priced at $864 found 15 hours ago
Sat, Nov 21 - Mon, Dec 7
LYS
Lyon
SAN
San Diego
$882 Roundtrip, found 15 hours ago
$882
Roundtrip
found 15 hours ago
Select Lufthansa flight, departing Sat, Nov 21 from Lyon to San Diego, returning Mon, Dec 7, priced at $882 found 15 hours ago
Sat, Nov 21 - Mon, Dec 7
LYS
Lyon
SAN
San Diego
$965 Roundtrip, found 15 hours ago
$965
Roundtrip
found 15 hours ago
Select Brussels Airlines flight, departing Sat, Nov 21 from Lyon to San Diego, returning Mon, Dec 7, priced at $965 found 15 hours ago
Sun, Jan 17 - Sat, Jan 23
LYS
Lyon
SAN
San Diego
$1,060 Roundtrip, found 2 days ago
$1,060
Roundtrip
found 2 days ago
Select Aer Lingus flight, departing Sun, Jan 17 from Lyon to San Diego, returning Sat, Jan 23, priced at $1,060 found 2 days ago
Sat, Nov 21 - Mon, Dec 7
LYS
Lyon
SAN
San Diego
$1,073 Roundtrip, found 15 hours ago
$1,073
Roundtrip
found 15 hours ago
Select TAP Portugal flight, departing Sat, Nov 21 from Lyon to San Diego, returning Mon, Dec 7, priced at $1,073 found 15 hours ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 28 to Sep 29
$211 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,340 reviews)
"Amazing location but the property is in need of some maintenance. Since we stayed here a year ago there is no longer an airport shuttle, and there are areas that need some attention such as the beds, bathrooms and elevators. Just starting to feel a bit dated."

Reviewed on Sep 22, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$103 nightly
The price is $119 total per night from Sep 28 to Sep 29
$119 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,937 reviews)
"Great for family!"

Reviewed on Sep 22, 2026

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$103 nightly
The price is $119 total per night from Sep 28 to Sep 29
$119 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,937 reviews)
"Great for family!"

Reviewed on Sep 22, 2026

Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 23 to Sep 24
$97 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,940 reviews)
"Property is old outdated. Room smell moldy and bathroom mildew. The only thing I like is free parking."

Reviewed on Sep 22, 2026

Best Western Seven Seas
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$254 nightly
The price is $292 total per night from Oct 4 to Oct 5
$292 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 28 to Sep 29
$211 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,340 reviews)
"Amazing location but the property is in need of some maintenance. Since we stayed here a year ago there is no longer an airport shuttle, and there are areas that need some attention such as the beds, bathrooms and elevators. Just starting to feel a bit dated."

Reviewed on Sep 22, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$141 nightly
The price is $162 total per night from Oct 1 to Oct 2
$162 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,089 reviews)
"I was very disappointed with the cleanliness of my room. One of the folded towels in the bathroom had a long strand of hair on it, while another towel appeared to have what looked like black mold or mildew. The bathtub was not properly cleaned, and the sink had old soap residue and even a chunk of ..."

Reviewed on Sep 22, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$78 nightly
The price is $89 total per night from Sep 27 to Sep 28
$89 total
Sep 27 - Sep 28
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Sep 23 to Sep 24
$81 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,210 reviews)
"Comfy"

Reviewed on Sep 21, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$99 nightly
The price is $113 total per night from Sep 29 to Sep 30
$113 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from Oct 21 to Oct 22
$257 total
Oct 21 - Oct 22
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
8.6/10 Excellent! (2,418 reviews)
"Our bayfront room was beautiful and comfortable. The front desk was very kind and sent a complimentary bottle of wine to our room as we celebrated our 25th anniversary, having been married on the William D Evans in 2001. Apart from the low pressure and lag in hot water coming out of the shower, and ..."

Reviewed on Sep 22, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$194 nightly
The price is $223 total per night from Sep 28 to Sep 29
$223 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$294 nightly
The price is $339 total per night from Sep 23 to Sep 24
$339 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,367 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"Location is so much Good safe walking to the bar restaurant and beach 😎 people vibe amazing"

Reviewed on Sep 22, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LYS to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Saint-Exupery Airport (LYS) to San Diego Airport?
Heading from Lyon Airport to San Diego Airport? Breaking up the trip is your only option as there are no airlines that service this route directly. However, British Airways, Lufthansa and Air Canada offer the best alternative — a flight with just a single stopover.
What is the shortest flight from LYS to San Diego Intl. Airport (SAN)?
With the shortest possible flight time from Lyon Airport to SAN being 13 hours and 12 minutes, it's smart to have a few in-flight survival strategies up your sleeve. Earplugs, a neck pillow and an eye-mask should be among the basic items that go into your hand luggage.
How many hours flight from LYS to San Diego Airport?
With an average flight time of 13 hours and 15 minutes, journeying from LYS to SAN is no short trip. Prepare for some long hours in the sky and think about using your air miles to upgrade.
What airlines have the most flights from Lyon Airport to San Diego Intl. Airport (SAN)?
You'll need to make at least one stopover if you're flying from Lyon to San Diego. For now, there are no airlines that offer nonstop flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.