Cheap flights from EWR to FLO (Newark Liberty Intl. Airport to Florence Regional)

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Cheap Flights from EWR to FLO starting at $118 One Way, $276 Round Trip

Prices starting at $276 for return flights and $118 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Feb 4 - Sun, Feb 8
EWR
New York
FLO
Florence
$276 Roundtrip, found 1 day ago
$276
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 4 from New York to Florence, returning Sun, Feb 8, priced at $276 found 1 day ago
Tue, Feb 3 - Mon, Feb 9
EWR
New York
FLO
Florence
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Feb 3 from New York to Florence, returning Mon, Feb 9, priced at $319 found 1 day ago
Thu, Feb 5 - Mon, Feb 9
EWR
New York
FLO
Florence
$323 Roundtrip, found 1 day ago
$323
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Feb 5 from New York to Florence, returning Mon, Feb 9, priced at $323 found 1 day ago
Wed, Feb 4 - Mon, Feb 9
EWR
New York
FLO
Florence
$327 Roundtrip, found 1 day ago
$327
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 4 from New York to Florence, returning Mon, Feb 9, priced at $327 found 1 day ago
Tue, Feb 3 - Sat, Feb 7
EWR
New York
FLO
Florence
$339 Roundtrip, found 1 day ago
$339
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Feb 3 from New York to Florence, returning Sat, Feb 7, priced at $339 found 1 day ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Feb 2 to Feb 3
$112 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,005 reviews)
Great location and well maintained property.

Reviewed on Jan 18, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Feb 1 to Feb 2
$146 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (614 reviews)
Didn't stay long enough to try any of the amenities that they offer.

Reviewed on Jan 11, 2026

Hotel Florence, Tapestry Collection by Hilton
Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.

Florence SC
$206 nightly
The price is $231 total per night from Jan 25 to Jan 26
$231 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this vacation home in Florence. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Old Greenwood Athletic Park and Drs Bruce and ...
9.8/10 Exceptional! (41 reviews)
Everything was great!

Reviewed on Nov 10, 2025

Walking distance from one of South Carolina's top Medical centers.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night from Jan 25 to Jan 26
$95 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,240 reviews)
Good but need better tv

Reviewed on Jan 19, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$96 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,194 reviews)
The staff was friendly and the room was clean.

Reviewed on Jan 19, 2026

Comfort Inn & Suites Florence Center Area
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$70 nightly
The price is $79 total per night from Jan 22 to Jan 23
$79 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,546 reviews)
It was a great place to stay

Reviewed on Jan 18, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Jan 25 to Jan 26
$63 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,000 reviews)
Room was good. No microwave tho. Staff was very courteous and helpful

Reviewed on Jan 9, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jan 22 to Jan 23
$68 total
Jan 22 - Jan 23
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (325 reviews)
Clean room, great for price, stayed with spouse, 2 children and two pets. You can hear cars pulling in and out of this location. There was a homeless guy asking for money but you can encounter that anywhere. No bugs, no concerns. :)

Reviewed on Dec 29, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Jan 22 to Jan 23
$74 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,005 reviews)
Very friendly and courteous lady at check in. Room was clean, window heat/cool unit worked.Would appreciate a larger than 1"x 2" piece of soap and a more friendly TV guide service

Reviewed on Jan 18, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Feb 8 to Feb 9
$119 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,006 reviews)
Yes very clean and friendly!

Reviewed on Jan 20, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$101 nightly
The price is $113 total per night from Jan 27 to Jan 28
$113 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (40 reviews)
Staff was great, the room was very clean and new

Reviewed on Jan 15, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Jan 22 to Jan 23
$74 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,005 reviews)
Very friendly and courteous lady at check in. Room was clean, window heat/cool unit worked.Would appreciate a larger than 1"x 2" piece of soap and a more friendly TV guide service

Reviewed on Jan 18, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

EWR to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
EWR Address & GPS
Address:
Building 1, Conrad Road
Newark NJ, 07114
United States
IATA Code:
EWR
Longitude:
-74.178753
Latitude:
40.689071
Time Zone:
America/New_York
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from Newark Airport to Florence Regional Airport?
Make the most of the opportunity to sit back and chill out on the flight from Newark to Florence. The shortest flight time from Liberty Intl. Airport (EWR) to Florence Regional Airport (FLO) is 3 hours, which gives you ample time to enjoy a red wine or get carried away with a good book.
How many hours flight from EWR to Florence Regional Airport?
It typically takes about 3 hours and 11 minutes to travel from Newark Airport to Florence Regional Airport. You'll be in the sky for some time, so take some entertainment, like a gripping novel or a podcast.
What airlines have the most flights from Newark Airport to Florence Regional Airport (FLO)?
Do some people-watching, have a coffee, get the blood flowing again ... Airport stopovers don't have to irritating! If you're planning to travel from Liberty Intl. Airport (EWR) to FLO, there are no direct flights. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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