Cheap flights from EWR to FLO (Newark Liberty Intl. Airport to Florence Regional)

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Cheap Flights from EWR to FLO starting at $312 One Way, $412 Round Trip

Prices starting at $412 for return flights and $312 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 13 - Sat, May 16
EWR
New York
FLO
Florence
$412 Roundtrip, found 1 day ago
$412
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 13 from New York to Florence, returning Sat, May 16, priced at $412 found 1 day ago
Tue, Apr 21 - Thu, Apr 23
EWR
New York
FLO
Florence
$428 Roundtrip, found 2 days ago
$428
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Apr 21 from New York to Florence, returning Thu, Apr 23, priced at $428 found 2 days ago
Wed, May 13 - Sat, May 16
EWR
New York
FLO
Florence
$454 Roundtrip, found 1 day ago
$454
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 13 from New York to Florence, returning Sat, May 16, priced at $454 found 1 day ago
Wed, May 13 - Sat, May 16
EWR
New York
FLO
Florence
$455 Roundtrip, found 1 day ago
$455
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 13 from New York to Florence, returning Sat, May 16, priced at $455 found 1 day ago
Wed, May 13 - Sat, May 16
EWR
New York
FLO
Florence
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 13 from New York to Florence, returning Sat, May 16, priced at $485 found 1 day ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$122 nightly
The price is $137 total per night from Apr 12 to Apr 13
$137 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,002 reviews)
Great location, parking is right next door and an easy walk. The staff were very friendly and accommodating. Much better than staying in a hotel near I-95

Reviewed on Apr 2, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Apr 26 to Apr 27
$146 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (624 reviews)
Not used

Reviewed on Mar 30, 2026

Hotel Florence, Tapestry Collection by Hilton
Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown

2 out of 5
415 S. IRBY ST Florence SC
$56 nightly
The price is $63 total per night from Apr 3 to Apr 4
$63 total
Apr 3 - Apr 4
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
4.6/10 (4 reviews)
Looks like the owners are doing a lot of work on the property however, cleanliness is doable but not done. Our room was supposed to have 2 beds in it but the first room we got looked like someone was still in it. Unmade bed, clothes on chair and a huge fan in the middle of the room. Second room, ...

Reviewed on Mar 11, 2026

Rodeway Inn Florence Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$65 nightly
The price is $72 total per night from May 3 to May 4
$72 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,605 reviews)
A very nice facility , clean . Nice stuff & pleasure working people

Reviewed on Apr 2, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$89 nightly
The price is $100 total per night from Apr 26 to Apr 27
$100 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,228 reviews)
The staff was fantastic. The breakfast was not worth mentioning - water downed eggs, kielbasa, fruit loops, toast... Our room had a problem with a very noisy a.c. Our curtains did not shut all the way, making it impossible to keep the light out.

Reviewed on Apr 2, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$98 nightly
The price is $109 total per night from Apr 26 to Apr 27
$109 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,240 reviews)
Parking was good. Staff was very friendly.

Reviewed on Mar 31, 2026

Comfort Inn & Suites Florence Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from May 3 to May 4
$63 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,001 reviews)
Lots of dining opportunities!

Reviewed on Apr 2, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Apr 5 to Apr 6
$68 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (331 reviews)
Check in was easy. Parking was easy. The room was clean. For a $72 room, I didn't mind that the microwave or fridge had cosmetic issues (I didn't need to use them). I work in hotels and found that everything was standard for a roadside motel. The one issue I had was my tub didn't have a drain. Not ...

Reviewed on Mar 23, 2026

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 8 to Apr 9
$74 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,002 reviews)
No AC in room, walls dirty, desk chair stained, old TV. This is a motel.

Reviewed on Apr 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$129 nightly
The price is $144 total per night from Apr 5 to Apr 6
$144 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
The heavy blinds we couldn’t put down so had the lights from outside shining in room

Reviewed on Mar 28, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from Apr 8 to Apr 9
$104 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (60 reviews)
Hotel was OK. Breakfast was slim. Very small selection, everything was fresh. Bed was comfy.

Reviewed on Mar 30, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 8 to Apr 9
$74 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,002 reviews)
No AC in room, walls dirty, desk chair stained, old TV. This is a motel.

Reviewed on Apr 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

EWR to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
EWR Address & GPS
Address:
Building 1, Conrad Road
Newark NJ, 07114
United States
IATA Code:
EWR
Longitude:
-74.178753
Latitude:
40.689071
Time Zone:
America/New_York
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from Newark Airport to Florence Regional Airport?
Make the most of the opportunity to sit back and chill out on the flight from Newark to Florence. The shortest flight time from Liberty Intl. Airport (EWR) to Florence Regional Airport (FLO) is 3 hours, which gives you ample time to enjoy a red wine or get carried away with a good book.
How many hours flight from EWR to Florence Regional Airport?
It typically takes about 3 hours and 11 minutes to travel from Newark Airport to Florence Regional Airport. You'll be in the sky for some time, so take some entertainment, like a gripping novel or a podcast.
What airlines have the most flights from Newark Airport to Florence Regional Airport (FLO)?
Do some people-watching, have a coffee, get the blood flowing again ... Airport stopovers don't have to irritating! If you're planning to travel from Liberty Intl. Airport (EWR) to FLO, there are no direct flights. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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