Cheap flights from DTW to GSP (Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl.)

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Cheap Flights from DTW to GSP starting at $187 One Way, $377 Round Trip

Prices starting at $377 for return flights and $187 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jan 20 - Wed, Jan 27
DTW
Detroit
GSP
Greenville
$377 Roundtrip, found 1 day ago
$377
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Jan 20 from Detroit to Greenville, returning Wed, Jan 27, priced at $377 found 1 day ago
Thu, Nov 26 - Tue, Dec 1
DTW
Detroit
GSP
Greenville
$381 Roundtrip, found 6 days ago
$381
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Thu, Nov 26 from Detroit to Greenville, returning Tue, Dec 1, priced at $381 found 6 days ago
Tue, Nov 24 - Thu, Dec 3
DTW
Detroit
GSP
Greenville
$409 Roundtrip, found 5 days ago
$409
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 24 from Detroit to Greenville, returning Thu, Dec 3, priced at $409 found 5 days ago
Wed, Jan 20 - Wed, Jan 27
DTW
Detroit
GSP
Greenville
$417 Roundtrip, found 1 day ago
$417
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Jan 20 from Detroit to Greenville, returning Wed, Jan 27, priced at $417 found 1 day ago
Thu, Nov 26 - Tue, Dec 1
DTW
Detroit
GSP
Greenville
$418 Roundtrip, found 6 days ago
$418
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Thu, Nov 26 from Detroit to Greenville, returning Tue, Dec 1, priced at $418 found 6 days ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
$91 nightly
The price is $101 total per night from Nov 29 to Nov 30
$101 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this golf hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Comfort Suites Greenville Airport
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd Greenville SC
$75 nightly
The price is $83 total per night from Nov 8 to Nov 9
$83 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Haywood Mall and BMW Performance ...
Woodspring Suites Greenville Airport
Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
$108 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,002 reviews)
"This hotel was an overnight stop for us on a road trip and it was prefect. The front desk staff both in the evening and the morning were extraordinarily helpful and friendly! The included breakfast was better than most and a convenient start to our day. The bathroom had plenty of towels (very helpful!) ..."

Reviewed on Nov 5, 2026

Hampton Inn & Suites Greenville Airport, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$98 nightly
The price is $108 total per night from Nov 15 to Nov 16
$108 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (865 reviews)
"There is a dumpster on one side of hotel that belongs to a shopping center and random people were throwing stuff in all day and night long and the lid would bang shut. Comfort inn needs to talk with the business’s who oversee and rent the dumpster to see about locking for only employees so people ..."

Reviewed on Oct 30, 2026

Comfort Inn & Suites Greer - Greenville
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$71 nightly
The price is $78 total per night from Dec 6 to Dec 7
$78 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
MainStay Suites Greenville Airport
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$97 nightly
The price is $107 total per night from Nov 29 to Nov 30
$107 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$97 nightly
The price is $107 total per night from Nov 29 to Nov 30
$107 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$98 nightly
The price is $108 total per night from Nov 15 to Nov 16
$108 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (865 reviews)
"There is a dumpster on one side of hotel that belongs to a shopping center and random people were throwing stuff in all day and night long and the lid would bang shut. Comfort inn needs to talk with the business’s who oversee and rent the dumpster to see about locking for only employees so people ..."

Reviewed on Oct 30, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$97 nightly
The price is $107 total per night from Nov 29 to Nov 30
$107 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$63 nightly
The price is $69 total per night from Dec 6 to Dec 7
$69 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DTW to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DTW Address & GPS
Address:
1 Detroit Metro Airport
Detroit MI, 48242
United States
IATA Code:
DTW
Longitude:
-83.356048
Latitude:
42.207808
Time Zone:
America/New_York
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Detroit Metropolitan Wayne County Airport (DTW) to GSP?
Delta Air Lines makes going from Detroit to Greenville easy. It offers direct flights from DTW to GSP, so you don't have to stress about swapping aircraft.
What is the shortest flight from Detroit Metro Airport to Roger Milliken Field?
Use the opportunity to sit back and relax on your flight from Detroit to Greenville. The quickest flight time from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) is 3 hours and 54 minutes, which gives you more than enough time to indulge in a tipple or lose yourself in a good book.
How many hours flight from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
There's no excuse not to book a Greer escape when the plane ride from DTW to GSP is just 4 hours and 3 minutes on average. So, go ahead and secure your seat — it's high time you finally took a break.
What airlines have the most flights from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Advertising 139 flights each month between DTW and GSP, Delta Air Lines will get you to your destination in comfort and style.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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