Cheap flights from DTW to GSP (Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl.)

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Cheap Flights from DTW to GSP starting at $74 One Way, $286 Round Trip

Prices starting at $286 for return flights and $74 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 17 - Tue, May 19
DTW
Detroit
GSP
Greenville
$286 Roundtrip, found 5 days ago
$286
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sun, May 17 from Detroit to Greenville, returning Tue, May 19, priced at $286 found 5 days ago
Sun, May 17 - Tue, May 19
DTW
Detroit
GSP
Greenville
$295 Roundtrip, found 5 days ago
$295
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sun, May 17 from Detroit to Greenville, returning Tue, May 19, priced at $295 found 5 days ago
Sat, May 9 - Tue, May 12
DTW
Detroit
GSP
Greenville
$353 Roundtrip, found 6 days ago
$353
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Sat, May 9 from Detroit to Greenville, returning Tue, May 12, priced at $353 found 6 days ago
Wed, Jul 8 - Sun, Jul 12
DTW
Detroit
GSP
Greenville
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 8 from Detroit to Greenville, returning Sun, Jul 12, priced at $367 found 1 day ago
Sun, May 17 - Tue, May 19
DTW
Detroit
GSP
Greenville
$368 Roundtrip, found 5 days ago
$368
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sun, May 17 from Detroit to Greenville, returning Tue, May 19, priced at $368 found 5 days ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
$101 nightly
The price is $111 total per night from Apr 26 to Apr 27
$111 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,001 reviews)
Good location. Plenty of parking! We had a trailer attached to our vehicle j there was plenty of space. Breakfast was decent & employees were pleasant. Room was clean.

Reviewed on Apr 14, 2026

Hampton Inn & Suites Greenville Airport, SC
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$60 nightly
The price is $66 total per night from Apr 26 to Apr 27
$66 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (672 reviews)
Room was not really clean ,the pillows had this perfume ,smelt like someone had used them and the trash can ,was not emptied,it felf like someone else used the room and it was not properly cleaned before we used it.

Reviewed on Apr 12, 2026

MainStay Suites Greenville Airport
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$114 nightly
The price is $125 total per night from Apr 19 to Apr 20
$125 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (838 reviews)
Breakfast was good. Hotel is a little older and could use some cosmetic upgrades, but everything was clean and comfortable for our family. Would stay here again.

Reviewed on Apr 1, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
$123 nightly
The price is $134 total per night from Apr 17 to Apr 18
$134 total
Apr 17 - Apr 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (656 reviews)
Breakfast menu was fresh, staff were great. The material on Expedia do not represent the breakfast accurately. It is an elevated Starbucks rather than a restaurant breakfast venue.

Reviewed on Apr 13, 2026

Courtyard Greenville-Spartanburg by Marriott
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$96 nightly
The price is $104 total per night from Apr 19 to Apr 20
$104 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (779 reviews)
Breakfast not available for our early flight at 6am. Bed were uncomfortable and the metal frames creaked every time you moved. Could also here the creaks from neighboring rooms

Reviewed on Apr 6, 2026

Comfort Inn & Suites Greer - Greenville
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$60 nightly
The price is $66 total per night from Apr 26 to Apr 27
$66 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (672 reviews)
Room was not really clean ,the pillows had this perfume ,smelt like someone had used them and the trash can ,was not emptied,it felf like someone else used the room and it was not properly cleaned before we used it.

Reviewed on Apr 12, 2026

MainStay Suites Greenville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$114 nightly
The price is $125 total per night from Apr 19 to Apr 20
$125 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (838 reviews)
Breakfast was good. Hotel is a little older and could use some cosmetic upgrades, but everything was clean and comfortable for our family. Would stay here again.

Reviewed on Apr 1, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$96 nightly
The price is $104 total per night from Apr 19 to Apr 20
$104 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (779 reviews)
Breakfast not available for our early flight at 6am. Bed were uncomfortable and the metal frames creaked every time you moved. Could also here the creaks from neighboring rooms

Reviewed on Apr 6, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$114 nightly
The price is $125 total per night from Apr 19 to Apr 20
$125 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (838 reviews)
Breakfast was good. Hotel is a little older and could use some cosmetic upgrades, but everything was clean and comfortable for our family. Would stay here again.

Reviewed on Apr 1, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$78 nightly
The price is $85 total per night from May 3 to May 4
$85 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (344 reviews)
Sheets stunk. Dirty. Good water pressure. Noisy. Apple juice was good.

Reviewed on Apr 4, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DTW to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DTW Address & GPS
Address:
1 Detroit Metro Airport
Detroit MI, 48242
United States
IATA Code:
DTW
Longitude:
-83.356048
Latitude:
42.207808
Time Zone:
America/New_York
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Detroit Metropolitan Wayne County Airport (DTW) to GSP?
Delta Air Lines makes going from Detroit to Greenville easy. It offers direct flights from DTW to GSP, so you don't have to stress about swapping aircraft.
What is the shortest flight from Detroit Metro Airport to Roger Milliken Field?
Use the opportunity to sit back and relax on your flight from Detroit to Greenville. The quickest flight time from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) is 3 hours and 54 minutes, which gives you more than enough time to indulge in a tipple or lose yourself in a good book.
How many hours flight from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
There's no excuse not to book a Greer escape when the plane ride from DTW to GSP is just 4 hours and 3 minutes on average. So, go ahead and secure your seat — it's high time you finally took a break.
What airlines have the most flights from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Advertising 139 flights each month between DTW and GSP, Delta Air Lines will get you to your destination in comfort and style.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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