Cheap flights from DTW to GSP (Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl.)

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Cheap Flights from DTW to GSP starting at $152 One Way, $289 Round Trip

Prices starting at $289 for return flights and $152 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Dec 10 - Mon, Dec 14
DTW
Detroit
GSP
Greenville
$289 Roundtrip, found 3 days ago
$289
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Dec 10 from Detroit to Greenville, returning Mon, Dec 14, priced at $289 found 3 days ago
Tue, Dec 1 - Thu, Dec 3
DTW
Detroit
GSP
Greenville
$310 Roundtrip, found 5 days ago
$310
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Dec 1 from Detroit to Greenville, returning Thu, Dec 3, priced at $310 found 5 days ago
Thu, Dec 10 - Mon, Dec 14
DTW
Detroit
GSP
Greenville
$316 Roundtrip, found 3 days ago
$316
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Dec 10 from Detroit to Greenville, returning Mon, Dec 14, priced at $316 found 3 days ago
Sat, Feb 27 - Wed, Mar 3
DTW
Detroit
GSP
Greenville
$321 Roundtrip, found 3 days ago
$321
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 27 from Detroit to Greenville, returning Wed, Mar 3, priced at $321 found 3 days ago
Thu, Dec 10 - Mon, Dec 14
DTW
Detroit
GSP
Greenville
$334 Roundtrip, found 3 days ago
$334
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Dec 10 from Detroit to Greenville, returning Mon, Dec 14, priced at $334 found 3 days ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
$91 nightly
The price is $101 total per night from Nov 29 to Nov 30
$101 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this golf hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Comfort Suites Greenville Airport
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$69 nightly
The price is $76 total per night from Nov 29 to Nov 30
$76 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (821 reviews)
"Staff was very helpful at all times."

Reviewed on Oct 29, 2026

MainStay Suites Greenville Airport
Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
$100 nightly
The price is $111 total per night from Nov 29 to Nov 30
$111 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn & Suites Greenville Airport, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$69 nightly
The price is $76 total per night from Nov 29 to Nov 30
$76 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (821 reviews)
"Staff was very helpful at all times."

Reviewed on Oct 29, 2026

MainStay Suites Greenville Airport
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$98 nightly
The price is $108 total per night from Nov 8 to Nov 9
$108 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$98 nightly
The price is $108 total per night from Nov 29 to Nov 30
$108 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$98 nightly
The price is $108 total per night from Nov 29 to Nov 30
$108 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$98 nightly
The price is $108 total per night from Nov 8 to Nov 9
$108 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$98 nightly
The price is $108 total per night from Nov 29 to Nov 30
$108 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$69 nightly
The price is $75 total per night from Nov 29 to Nov 30
$75 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DTW to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DTW Address & GPS
Address:
1 Detroit Metro Airport
Detroit MI, 48242
United States
IATA Code:
DTW
Longitude:
-83.356048
Latitude:
42.207808
Time Zone:
America/New_York
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Detroit Metropolitan Wayne County Airport (DTW) to GSP?
Delta Air Lines makes going from Detroit to Greenville easy. It offers direct flights from DTW to GSP, so you don't have to stress about swapping aircraft.
What is the shortest flight from Detroit Metro Airport to Roger Milliken Field?
Use the opportunity to sit back and relax on your flight from Detroit to Greenville. The quickest flight time from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) is 3 hours and 54 minutes, which gives you more than enough time to indulge in a tipple or lose yourself in a good book.
How many hours flight from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
There's no excuse not to book a Greer escape when the plane ride from DTW to GSP is just 4 hours and 3 minutes on average. So, go ahead and secure your seat — it's high time you finally took a break.
What airlines have the most flights from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Advertising 139 flights each month between DTW and GSP, Delta Air Lines will get you to your destination in comfort and style.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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