$149 Cheap flight deals from San Francisco (SJC) to Key West (EYW)

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This Weekend's Flight Deals from San Francisco to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 2 - Wed, Aug 6
SFO
San Francisco Intl.
EYW
Key West Intl.
$453 Roundtrip, found 5 days ago
$453
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug 2 from San Francisco Intl. to Key West Intl., returning Wed, Aug 6, priced at $453 found 5 days ago
Sun, Aug 3 - Wed, Aug 6
OAK
Oakland Intl.
EYW
Key West Intl.
$854 Roundtrip, found 5 days ago
$854
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Aug 3 from Oakland Intl. to Key West Intl., returning Wed, Aug 6, priced at $854 found 5 days ago

Airfares from $149 One Way, $273 Round Trip from San Francisco to Key West

Prices starting at $273 for return flights and $149 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Sep 21 - Wed, Sep 24
SFO
San Francisco
EYW
Key West
$273 Roundtrip, found 12 hours ago
$273
Roundtrip
found 12 hours ago
Select Delta flight, departing Sun, Sep 21 from San Francisco to Key West, returning Wed, Sep 24, priced at $273 found 12 hours ago
Sun, Sep 21 - Sat, Sep 27
SFO
San Francisco
EYW
Key West
$284 Roundtrip, found 10 hours ago
$284
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Sun, Sep 21 from San Francisco to Key West, returning Sat, Sep 27, priced at $284 found 10 hours ago
Tue, Sep 23 - Wed, Sep 24
SFO
San Francisco
EYW
Key West
$294 Roundtrip, found 12 hours ago
$294
Roundtrip
found 12 hours ago
Select Delta flight, departing Tue, Sep 23 from San Francisco to Key West, returning Wed, Sep 24, priced at $294 found 12 hours ago
Sun, Sep 21 - Sat, Sep 27
SFO
San Francisco
EYW
Key West
$299 Roundtrip, found 10 hours ago
$299
Roundtrip
found 10 hours ago
Select Delta flight, departing Sun, Sep 21 from San Francisco to Key West, returning Sat, Sep 27, priced at $299 found 10 hours ago
Sun, Sep 21 - Sat, Sep 27
SFO
San Francisco
EYW
Key West
$309 Roundtrip, found 10 hours ago
$309
Roundtrip
found 10 hours ago
Select United flight, departing Sun, Sep 21 from San Francisco to Key West, returning Sat, Sep 27, priced at $309 found 10 hours ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Orchid Key Inn - Adults Only
3.5-star property

Orchid Key Inn - Adults Only

9.8/10 Exceptional! (1,005 reviews)

Sep 15 - Sep 17

2 night stay

San Francisco (SFO) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
per person
found 1 day ago
Great place. Very cool retro motel that’s been renovated. Room was a little small but very comfortable and clean. There’s a nice bar with great cocktails. Staff are friendly and attentive. The location was great. Central to everything and very walkable to most of the popular sites.

Reviewed on Jan 20, 2025

Atlantic Paradise by Avantstay Great Location w/ Balcony, Outdoor Dining & Shared Pool & Hot Tub!
3.0-star property

Atlantic Paradise by Avantstay Great Location w/ Balcony, Outdoor Dining & Shared Pool & Hot Tub!

10/10 Exceptional! (5 reviews)

Sep 4 - Sep 7

3 night stay

San Francisco (SFO) to Key West (EYW)

Delta • Non-stop • Coach

Key West (EYW) to San Francisco (SFO)

American Airlines • Non-stop • Coach
per person
found 1 day ago
Almond Tree Inn Hotel - Adults Only
3.5-star property

Almond Tree Inn Hotel - Adults Only

10/10 Exceptional! (1,002 reviews)

Sep 15 - Sep 17

2 night stay

San Francisco (SFO) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
per person
found 1 day ago
As always, Almond Tree Inn was a bright spot in our latest trip to Key West. I’ve stayed here several times over the years and everything about Almond Tree is top notch, from the superbly attentive and friendly staff to the well-appointed and maintained property. You always feel special staying here and this trip was no exception. As Florida locals, we look forward to our stays with you each and every time- THANK YOU!

Reviewed on May 26, 2025

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More About Flying To Key West from San Francisco

Route Information for Flights from San Francisco to Key West

Origin Airport IATA Code
SJC
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

San Francisco to Key West

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You can always find affordable flights from San Francisco to Key West on Orbitz. Use different airlines to book arrival and departure flights, take advantage of vacation package deals, and secure exclusive rewards.

Frequently asked questions

Am I able to catch a flight from San Francisco to Key West now?
If you're wondering about travel restrictions and quarantine requirements when traveling by plane from San Francisco to Key West, check out the Covid-19 Travel Advisor.
What is the shortest flight from San Francisco to Key West?
The fastest flight time from San Francisco Airport to Key West Intl. Airport is 6 hours and 11 minutes, which gives you more than enough time to indulge in a tipple or get swept up in a good movie.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you'll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.