Hotels in Depew
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Top Rated Depew Hotels

Buffalo Airport Hotel
4600 Genesee St Buffalo NY
Free Cancellation
Reserve now, pay when you stay
2.49 mi from city center
$90 nightly
The price is $102 total per night
$102 total
Feb 11 - Feb 12
Total with taxes and fees
Guests of Buffalo Airport Hotel enjoy a 24-hour gym, free WiFi in public areas, and meeting rooms. There's free parking, as well as a free airport shuttle (available 24 hours). Multilingual staff at the 24-hour front desk can assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Free airport shuttle
Parking included

Sleep Inn & Suites Buffalo Airport
100 Holtz Dr Buffalo NY
Free Cancellation
2.62 mi from city center
$80 nightly
The price is $91 total per night
$91 total
Mar 8 - Mar 9
Total with taxes and fees
Sleep Inn & Suites Buffalo Airport features a gym, free WiFi in public areas, and a 24-hour business center. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include coffee/tea in a common area, a microwave in a common area, and a meeting room.
Breakfast included
Free airport shuttle

Garden Place Hotel
6615 Transit Road Buffalo NY
Free Cancellation
Reserve now, pay when you stay
3.28 mi from city center
$95 nightly
The price is $108 total per night
$108 total
Feb 11 - Feb 12
Total with taxes and fees
Guests staying at Garden Place Hotel enjoy a 24-hour gym, a sauna, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The front desk is staffed 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include a business center, a meeting room, and express check-out.
Free airport shuttle
Pet friendly

Hyatt Regency Buffalo / Hotel and Conference Center
Two Fountain Plaza Buffalo NY
Free Cancellation
Reserve now, pay when you stay
8.61 mi from city center
$143 nightly
The price is $167 total per night
$167 total
Feb 11 - Feb 12
Total with taxes and fees
At Hyatt Regency Buffalo / Hotel and Conference Center, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 29.50 per night. The front desk has multilingual staff on hand 24/7 to help with concierge services, securing valuables, and luggage storage. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Pet friendly

M Hotel Buffalo
2040 Walden Ave Buffalo NY
Free Cancellation
Reserve now, pay when you stay
2.89 mi from city center
$99 nightly
The price is $113 total per night
$113 total
Feb 11 - Feb 12
Total with taxes and fees
Guests of M Hotel Buffalo have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included

La Quinta Inn by Wyndham Buffalo Airport
6619 Transit Rd Buffalo NY
Free Cancellation
Reserve now, pay when you stay
3.32 mi from city center
$76 nightly
The price is $86 total per night
$86 total
Feb 17 - Feb 18
Total with taxes and fees
Renovated in 2024, La Quinta Inn by Wyndham Buffalo Airport offers a gym, free WiFi in public areas, and a 24-hour business center. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include coffee/tea in a common area, express check-in, and express check-out.
Breakfast included
Free airport shuttle

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
131 Buell Ave Buffalo NY
Free Cancellation
2.57 mi from city center
$91 nightly
The price is $104 total per night
$104 total
Mar 1 - Mar 2
Total with taxes and fees
Guests of Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of extended parking for a fee, along with a free airport shuttle (available on request). The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Homewood Suites by Hilton Buffalo/Amherst
1138 Millersport Hwy Buffalo NY
Free Cancellation
Reserve now, pay when you stay
7.37 mi from city center
$130 nightly
The price is $148 total per night
$148 total
Feb 22 - Feb 23
Total with taxes and fees
At Homewood Suites by Hilton Buffalo/Amherst, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Tru by Hilton Williamsville Buffalo Airport
48 Freeman Road Buffalo NY
Free Cancellation
Reserve now, pay when you stay
3.51 mi from city center
$98 nightly
The price is $111 total per night
$111 total
Feb 16 - Feb 17
Total with taxes and fees
At Tru by Hilton Williamsville Buffalo Airport, guests enjoy an indoor pool, a gym, and free WiFi in public areas. There's free parking, as well as a free airport shuttle (available on request). The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Buffalo Amherst
145 Innkeepers Lane Buffalo NY
Free Cancellation
Reserve now, pay when you stay
9.2 mi from city center
$89 nightly
The price is $102 total per night
$102 total
Feb 16 - Feb 17
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Buffalo Amherst have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24/7 to help with concierge services, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, laundry facilities, and a convenience store.
Pool
Breakfast included

Wyndham Garden Buffalo Downtown
125 High St Buffalo NY
Free Cancellation
Reserve now, pay when you stay
8.07 mi from city center
$124 nightly
The price is $144 total per night
$144 total
Feb 16 - Feb 17
Total with taxes and fees
At Wyndham Garden Buffalo Downtown, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. Valet parking is USD 25.00 per day if you plan to drive, or hop aboard the airport shuttle at scheduled times for USD 30.00 per room one-way. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and concierge services. Additional amenities include coffee/tea in a common area, express check-in, and express check-out.
Breakfast included
Free WiFi

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
601 Main St Buffalo NY
Free Cancellation
8.51 mi from city center
$125 nightly
The price is $146 total per night
$146 total
Mar 1 - Mar 2
Total with taxes and fees
Guests of Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG enjoy a gym, free WiFi in public areas, and a business center. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include express check-out, laundry facilities, and a vending machine.
Breakfast included
Free WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What's the best place for a stay in Depew?
What are some favorite hotels in downtown Depew?
These are some of our travelers' favorite hotels in downtown Depew:
- Buffalo Airport Hotel is hotel has free WiFi, free parking, and a 24-hour fitness center.
- Garden Place Hotel is hotel has free parking, a 24-hour fitness center, and a free airport shuttle.
- La Quinta Inn by Wyndham Buffalo Airport is hotel has free breakfast, free WiFi, and free parking.
Depew hotels essential information
Accommodation | 879 hotels |
|---|---|
Lowest Price | $86 |
Highest Price | $167 |
Popular hotels | Buffalo Airport Hotel, Sleep Inn & Suites Buffalo Airport, Garden Place Hotel, Hyatt Regency Buffalo / Hotel and Conference Center, M Hotel Buffalo, La Quinta Inn by Wyndham Buffalo Airport, Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG, Homewood Suites by Hilton Buffalo/Amherst, Tru by Hilton Williamsville Buffalo Airport, La Quinta Inn & Suites by Wyndham Buffalo Amherst, Wyndham Garden Buffalo Downtown, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG |
Recent Reviews

Sleep Inn & Suites Buffalo Airport
5/5 Excellent
"Great staff, wonderful vibe and terrific breakfast :)"
A verified traveler stayed at Sleep Inn & Suites Buffalo Airport
Posted 3 days ago
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