Hotels in San Diego Santa Fe Depot
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Tomorrow night
Check prices close to San Diego Santa Fe Depot for tomorrow night, Apr 5 - Apr 6Hotels near San Diego Santa Fe Depot

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
5.75 mi from San Diego Santa Fe Depot
$273 nightly
The price is $314 total per night
$314 total
Apr 26 - Apr 27
Total with taxes and fees
Paradise Point Resort & Spa features a marina, a full-service spa, and 5 outdoor pools. Self parking is available for USD 49 per night. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Other amenities at this beach resort include a gym, 5 hot tubs, and a sauna.

Best Western Seven Seas
411 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
3.08 mi from San Diego Santa Fe Depot
$82 nightly
The price is $94 total per night
$94 total
Apr 13 - Apr 14
Total with taxes and fees
Guests of Best Western Seven Seas have access to an outdoor pool, a gym, and 2 hot tubs. Free parking is included with your stay. The front desk has multilingual staff on hand 24/7 to help with luggage storage, tours or tickets, and securing valuables. Additional amenities include free WiFi in public areas, conference space, and a business center.

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.8 mi from San Diego Santa Fe Depot
$248 nightly
The price is $287 total per night
$287 total
Apr 5 - Apr 6
Total with taxes and fees
Hard Rock Hotel San Diego features a nightclub, an outdoor pool, and a 24-hour gym. Valet parking is offered for USD 70 per night. Multilingual staff at the 24-hour front desk can assist with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.

Handlery Hotel
950 Hotel Cir N San Diego CA
3.06 mi from San Diego Santa Fe Depot
$129 nightly
The price is $148 total per night
$148 total
Apr 13 - Apr 14
Total with taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, luggage storage, and concierge services. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
0.54 mi from San Diego Santa Fe Depot
$135 nightly
The price is $157 total per night
$157 total
Apr 23 - Apr 24
Total with taxes and fees
Guests of The DEXTRO Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with tours/tickets and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
Free Cancellation
Reserve now, pay when you stay
3.06 mi from San Diego Santa Fe Depot
$103 nightly
The price is $118 total per night
$118 total
Apr 6 - Apr 7
Total with taxes and fees
At Days Inn by Wyndham San Diego Hotel Circle, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 20 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and concierge services. Additional amenities include a hot tub, conference space, and a business center.

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from San Diego Santa Fe Depot
$236 nightly
The price is $274 total per night
$274 total
Apr 6 - Apr 7
Total with taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, concierge services, and securing valuables. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
$182 nightly
The price is $211 total per night
$211 total
Apr 6 - Apr 7
Total with taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 50.00 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, dry cleaning/laundry, and concierge services. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Pet friendly

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.83 mi from San Diego Santa Fe Depot
$185 nightly
The price is $213 total per night
$213 total
Apr 12 - Apr 13
Total with taxes and fees
Guests of Sheraton San Diego Resort have access to a marina, 3 outdoor pools, and a 24-hour gym. Parking is USD 55 per night (USD 67 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle during limited hours. Multilingual staff at the 24-hour front desk can assist with luggage storage, dry cleaning/laundry, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Port of San Diego
4.5/5(1,650 reviews)
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Navy Pier
4.5/5(29 reviews)
After visiting Navy Pier, make a plan to see the other sights and activities in San Diego. Discover the area's top-notch restaurants and its fascinating museums.

B Street Cruise Ship Terminal
4.5/5(163 reviews)
Explore the waterfront in San Diego with a trip to B Street Cruise Ship Terminal. Stroll along the area's beautiful beaches, or simply savor its top-notch restaurants.
Hotels Great for Sightseeing Near San Diego Santa Fe Depot

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Apr 6 to Apr 7
$211 total
Apr 6 - Apr 7
Total with taxes and fees
8.4/10 Very Good! (6,120 reviews)

Gaslamp Plaza Suites
520 E St San Diego CA
$119 nightly
The price is $135 total per night from Apr 6 to Apr 7
$135 total
Apr 6 - Apr 7
Total with taxes and fees
9/10 Wonderful! (1,025 reviews)

Springhill Suites San Diego Downtown/Bayfront
900 Bayfront Court San Diego CA
$215 nightly
The price is $250 total per night from Apr 23 to Apr 24
$250 total
Apr 23 - Apr 24
Total with taxes and fees
9.2/10 Wonderful! (1,003 reviews)
Vacation Rentals Near San Diego Santa Fe Depot

Sentral Gaslamp Quarter
502 10th Avenue San Diego CA
$152 nightly
The price is $176 total per night from Apr 5 to Apr 6
$176 total
Apr 5 - Apr 6
Total with taxes and fees
9.4/10 Exceptional! (813 reviews)

Marriott Vacation Club®, San Diego
701 A St San Diego CA
$169 nightly
The price is $196 total per night from Apr 23 to Apr 24
$196 total
Apr 23 - Apr 24
Total with taxes and fees
9.4/10 Exceptional! (1,049 reviews)

Kasa Little Italy San Diego
1331 Columbia St San Diego CA
$260 nightly
The price is $296 total per night from Apr 5 to Apr 6
$296 total
Apr 5 - Apr 6
Total with taxes and fees
9.6/10 Exceptional! (400 reviews)
Historic San Diego Santa Fe Depot Hotels

The Horton Grand, Downtown/Gaslamp Quarter
311 Island Ave San Diego CA
$157 nightly
The price is $182 total per night from Apr 5 to Apr 6
$182 total
Apr 5 - Apr 6
Total with taxes and fees
9.2/10 Wonderful! (2,792 reviews)

The Sofia Hotel
150 W Broadway San Diego CA
$136 nightly
The price is $158 total per night from Apr 6 to Apr 7
$158 total
Apr 6 - Apr 7
Total with taxes and fees
8.6/10 Excellent! (1,881 reviews)

Gaslamp Plaza Suites
520 E St San Diego CA
$119 nightly
The price is $135 total per night from Apr 6 to Apr 7
$135 total
Apr 6 - Apr 7
Total with taxes and fees
9/10 Wonderful! (1,025 reviews)
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,927 hotels |
|---|---|
Lowest Price | $94 |
Highest Price | $314 |
Popular hotels | Paradise Point Resort & Spa, Best Western Seven Seas, Hard Rock Hotel San Diego, Handlery Hotel, The DEXTRO Little Italy, BW Premier Collection, Days Inn by Wyndham San Diego Hotel Circle, Manchester Grand Hyatt San Diego, Wyndham San Diego Bayside, Sheraton San Diego Resort |
Recent Reviews

The DEXTRO Little Italy, BW Premier Collection
5/5 Excellent
"Good "
A verified traveler stayed at The DEXTRO Little Italy, BW Premier Collection
Posted 2 hours ago
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