COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Check restrictions for your trip.Opens in new tab or window

South Carolina Vacation Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top cities in South Carolina

    Myrtle Beach showing general coastal views, swimming and a city
    Vacation RentalsVacation Rentals
    Myrtle Beach
    Aug 15 - Aug 16
    from $169
    per night/room
    Myrtle Beach
    Charleston
    Vacation RentalsVacation Rentals
    Charleston
    Aug 9 - Aug 10
    from $101
    per night/room
    Charleston
    Greenville which includes a river or creek, a city and a bridge
    Vacation RentalsVacation Rentals
    Greenville
    Aug 16 - Aug 17
    from $50
    per night/room
    Greenville
    Vacation RentalsVacation Rentals
    Beaufort
    Aug 14 - Aug 15
    from $128
    per night/room
    Beaufort
    Hilton Head which includes general coastal views and a beach as well as an individual femail
    Vacation RentalsVacation Rentals
    Hilton Head
    Aug 31 - Sep 1
    from $169
    per night/room
    Hilton Head
    South Carolina State House
    Vacation RentalsVacation Rentals
    Columbia
    Aug 10 - Aug 11
    from $89
    per night/room
    Columbia

South Carolina Vacation Rentals

Ocean Enclave by Hilton Grand Vacations

Ocean Enclave by Hilton Grand Vacations

4 out of 5
1600 Ocean Blvd, Myrtle Beach, SC
The price is $271 per night
Guests of Ocean Enclave by Hilton Grand Vacations have access to 2 outdoor pools, a fitness center, and a 24-hour business center. Valet parking is available for USD 21.80 per day. The 24-hour front desk has multilingual staff ready to assist with securing valuables and luggage storage. Other amenities at this beach aparthotel include a free kid's club, laundry facilities, and an ATM.
Home2 Suites by Hilton Charleston West Ashley

Home2 Suites by Hilton Charleston West Ashley

2.5 out of 5
1963 Savannah Highway, Charleston, SC
Free Cancellation
Reserve now, pay when you stay
The price is $106 per night
Built in 2018, the brand new Home2 Suites by Hilton Charleston West Ashley offers an outdoor pool, a 24-hour fitness center, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and express check-out.
Sheraton Broadway Plantation Resort Villas

Sheraton Broadway Plantation Resort Villas

3.5 out of 5
3301 Robert M Grissom Pkwy, Myrtle Beach, SC
The price is $289 per night
Sheraton Broadway Plantation Resort Villas features an indoor pool, an outdoor pool, and a lazy river. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, concierge services, and luggage storage. Other amenities at this family-friendly aparthotel include a children's pool, a fitness center, and a spa tub.
Royale Palms Condominiums

Royale Palms Condominiums

3.5 out of 5
10000 Beach Club Drive Tower 2, Myrtle Beach, SC
Free Cancellation
Reserve now, pay when you stay
The price is $264 per night
Guests of Royale Palms Condominiums enjoy a private beach, an indoor pool, and an outdoor pool. Parking is available for USD 9.99 per night (USD 15 per day for valet parking), and there's also an area shuttle. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Other amenities at this beach aparthotel include a health club, a spa tub, and free WiFi in public areas.
Driftwood and Tides Condos by Sea Mist Resort

Driftwood and Tides Condos by Sea Mist Resort

3 out of 5
305 13th Avenue South, Myrtle Beach, SC
The price is $218 per night
Driftwood and Tides Condos by Sea Mist Resort features 2 indoor pools, 9 outdoor pools, and a free water park. Self parking is available for USD 5.00 per day. The 24-hour front desk has staff always at the ready. Other amenities at this family-friendly aparthotel include a lazy river, a children's pool, and 3 spa tubs.
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

2.5 out of 5
900 Woody Jones Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
The price is $105 per night
Built in 2014, the brand new Home2 Suites by Hilton Florence, SC offers an indoor pool, a 24-hour fitness center, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with tours or tickets, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, an arcade/game room, and laundry facilities.
Myrtle Beach Resort Vacations

Myrtle Beach Resort Vacations

3 out of 5
5905 S Kings Hwy, Myrtle Beach, SC
Myrtle Beach Resort Vacations features 2 indoor pools, 4 outdoor pools, and a free water park. There's free parking if you drive. Staff members can help with accommodation requests, and provide front-desk service during limited hours. Other amenities at this beach condominium resort include karaoke, a lazy river, and a children's pool.
Home2 Suites by Hilton Summerville

Home2 Suites by Hilton Summerville

2.5 out of 5
221 Holiday Drive, Summerville, SC
Free Cancellation
Reserve now, pay when you stay
The price is $101 per night
Built in 2017, the brand new Home2 Suites by Hilton Summerville offers an indoor pool, a 24-hour fitness center, and free WiFi in public areas. Self parking is offered for USD 10 per day. The 24-hour front desk has staff always at the ready. Additional amenities include conference space, a 24-hour business center, and laundry facilities.
Oceans One Resort

Oceans One Resort

3 out of 5
102 South Ocean Boulevard, Myrtle Beach, SC
The price is $290 per night
Oceans One Resort features an indoor pool, an outdoor pool, and a lazy river. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. Other amenities at this beach condo building include a children's pool, a fitness center, and 2 spa tubs.
Sandy Beach Oceanfront Resort

Sandy Beach Oceanfront Resort

3.5 out of 5
201 South Ocean Blvd., Myrtle Beach, SC
Guests of Sandy Beach Oceanfront Resort have access to 2 indoor pools, 3 outdoor pools, and a lazy river. The front desk is staffed 24/7 to help with tours or tickets, and answer any questions about the accommodations. Other amenities at this beach condo building include a children's pool, a fitness center, and free WiFi in public areas.
Home2 Suites by Hilton Rock Hill

Home2 Suites by Hilton Rock Hill

2.5 out of 5
1285 Old Springdale Rd, Rock Hill, SC
Free Cancellation
Reserve now, pay when you stay
The price is $107 per night
Built in 2017, the brand new Home2 Suites by Hilton Rock Hill offers an indoor pool, a 24-hour fitness center, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a meeting room, a business center, and coffee/tea in a common area.
Home2 Suites by Hilton Hilton Head

Home2 Suites by Hilton Hilton Head

2.5 out of 5
836 William Hilton Parkway, Hilton Head Island, SC
Free Cancellation
Reserve now, pay when you stay
The price is $183 per night
Guests of Home2 Suites by Hilton Hilton Head have access to an outdoor pool, a 24-hour fitness center, and free WiFi in public areas. You can take advantage of free parking, along with a free area shuttle. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a business center, a computer station, and free newspapers.
Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston

2.5 out of 5
1650 James Nelson Road, Mount Pleasant, SC
Free Cancellation
Reserve now, pay when you stay
The price is $135 per night
Built in 2017, the brand new Home2 Suites By Hilton Mt Pleasant Charleston offers an outdoor pool, a 24-hour fitness center, and free WiFi in public areas. If you drive, take advantage of free parking. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry and securing valuables. Additional amenities include a 24-hour business center, coffee/tea in a common area, and free newspapers.
Ocean Villas Beach Resort, a VRI resort

Ocean Villas Beach Resort, a VRI resort

3 out of 5
7509 N. Ocean Blvd., Myrtle Beach, SC
At this apartment, guests have access to an outdoor pool, laundry facilities, and barbecue grills. If you plan to drive, free parking is available.
TownePlace Suites by Marriott Charleston-North Charleston

TownePlace Suites by Marriott Charleston-North Charleston

2.5 out of 5
7535 Northside Drive, North Charleston, SC
Free Cancellation
Reserve now, pay when you stay
The price is $109 per night
At TownePlace Suites by Marriott Charleston-North Charleston, guests enjoy an outdoor pool, a fitness center, and free WiFi in public areas. Free parking is included with your stay. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Home2 Suites by Hilton Columbia Harbison

Home2 Suites by Hilton Columbia Harbison

2.5 out of 5
550 Columbiana Dr, Columbia, Irmo, SC
Free Cancellation
Reserve now, pay when you stay
The price is $101 per night
Built in 2018, the brand new Home2 Suites by Hilton Columbia Harbison offers an indoor pool, a 24-hour fitness center, and free WiFi in public areas. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a meeting room, a business center, and coffee/tea in a common area.
Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island

2.5 out of 5
120 FAIRCHILD STREET, Charleston, SC
Free Cancellation
Reserve now, pay when you stay
The price is $162 per night
Built in 2019, the brand new Home2 Suites by Hilton Charleston Daniel Island offers an outdoor pool, a 24-hour fitness center, and free WiFi in public areas. There's free parking, as well as a free airport shuttle during limited hours. Staff members are on hand to provide dry cleaning/laundry services and a safe deposit box at the front desk. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a computer station.
Yachtsman Ocean Front Resort

Yachtsman Ocean Front Resort

3 out of 5
1304 North Ocean Boulevard, Myrtle Beach, SC
Guests staying at Yachtsman Ocean Front Resort enjoy access to 2 outdoor pools, an indoor pool, and a spa tub. Free parking is available if you drive. Friendly staff can provide front-desk service during limited hours, and also offer advice about sightseeing. Other amenities at this beach vacation home include free WiFi in public areas, a library, and laundry facilities.
Don't see what you're looking for?
See all available properties in South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orbitz makes it easy to find vacation rentals in South Carolina 

🏠 What is the best price for a South Carolina vacation rental?


South Carolina rentals range between $101 and $290 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in South Carolina can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next South Carolina getaway. Orbitz filters your search results so you can find the best South Carolina vacation rental for you. We have tons of options.


🏠 Are cancellations free on South Carolina vacation rentals with Orbitz?


You may be able to cancel or amend your South Carolina vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in South Carolina?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in South Carolina by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My Trips on your Orbitz account page to find the right information contact. If you need more help, visit our Customer Service page. 


🏠 What are the advantages of booking a vacation rental in South Carolina?


When you book a South Carolina vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in South Carolina?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across South Carolina—with plenty of hidden gems. We also have plenty of inventory in South Carolina main cities and near popular attraction spots.


🏠 Why should I book my South Carolina vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream South Carolina vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


Hotel Options in South Carolina

    Days Inn by Wyndham Charleston Historic District

    Days Inn by Wyndham Charleston Historic District

    155 Meeting St, Charleston, SC
    The price is $135 per night from Aug 3 to Aug 3
    3.3/5 (74 reviews)
    Days Inn by Wyndham Charleston Historic District
    Sandcastle Oceanfront Resort South Beach

    Sandcastle Oceanfront Resort South Beach

    2207 S Ocean Blvd, Myrtle Beach, SC
    The price is $159 per night from Sep 2 to Sep 2
    3.3/5 (89 reviews)
    Sandcastle Oceanfront Resort South Beach
    Sea Mist Oceanfront Resort

    Sea Mist Oceanfront Resort

    305 13th Ave. South, Myrtle Beach, SC
    The price is $229 per night from Aug 25 to Aug 25
    2/5 (104 reviews)
    Sea Mist Oceanfront Resort