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Sep 20 - Sep 22
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Top Rated Depew Hotels

Pink Fountain Motor Inn
Pink Fountain Motor Inn
2.0 out of 5.0 5474 Transit Rd, Depew, NY
Free Cancellation
$49
2.3/5 (7 reviews)

motel location was very convenient. this is my 2nd time i've stayed at the Pink Fountain.

Reviewed on Jun 17, 2018
At Pink Fountain Motor Inn, guests have access to a spa tub, free WiFi in public areas, and express check-in. If you drive, put free parking to good use. Front-desk ...
Quiet Suburban Home 10 Minutes From Airport/25 min From Niagara Falls
Quiet Suburban Home 10 Minutes From Airport/25 min From Niagara Falls
Depew, NY
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This apartment is a smoke-free apartment building.
Millennium Buffalo
Millennium Buffalo
3.5 out of 5.0 2040 Walden Ave, Buffalo, NY
Free Cancellation
$84
4.0/5 (53 reviews)

We stayed for one night but it was beautiful! Nice and clean. Definitely will be going back!

Reviewed on Sep 11, 2019
Guests of Millennium Buffalo have access to an indoor pool, a 24-hour fitness center, and a sauna. There's free parking, as well as a free airport shuttle (available ...
Buffalo Grand Hotel
Buffalo Grand Hotel
3.0 out of 5.0 120 Church St, Buffalo, NY
Free Cancellation
$82
3.1/5 (203 reviews)

Great price, located near everything downtown and canal side. Found a lot of dust on the vent in the bathroom, a/c noisy with facia falling off, even with the window closed I could hear all the noise on street, shower curtain rod kinda held in place with electrical tape but all in all a great place ...

Reviewed on Sep 5, 2019
Guests of Buffalo Grand Hotel have access to an indoor pool, a 24-hour health club, and a sauna. Self parking is offered for USD 15 per night. Front-desk staff ...
Days Hotel by Wyndham Buffalo Airport
Days Hotel by Wyndham Buffalo Airport
3.0 out of 5.0 4345 Genesee St, Buffalo, NY
$79
3.7/5 (126 reviews)

Breakfast started at 4 am and was very good. Personnel were to a person super nice. Overall the property was just a little tired.

Reviewed on Sep 11, 2019
Guests staying at Days Hotel by Wyndham Buffalo Airport enjoy an indoor pool, a fitness center, and a spa tub. There's free parking, as well as a free airport ...
Radisson Hotel Niagara Falls-Grand Island
Radisson Hotel Niagara Falls-Grand Island
3.0 out of 5.0 100 Whitehaven Rd, Grand Island, NY
Free Cancellation
$71
3.2/5 (62 reviews)

Pool was filled with algie. Residents of island were in control of pool.

Reviewed on Sep 5, 2019
Radisson Hotel Niagara Falls-Grand Island features an indoor pool, an outdoor pool, and a children's pool. If you plan to drive, free parking is available. The ...
Four Points by Sheraton Niagara Falls
Four Points by Sheraton Niagara Falls
3.0 out of 5.0 7001 Buffalo Ave, Niagara Falls, NY
Free Cancellation
$67
3.8/5 (54 reviews)

Great views. Awesome pool that is open late. The elevators were a bit slow at peak time with alot of traffic at the hotel,

Reviewed on Aug 9, 2019
At Four Points by Sheraton Niagara Falls, guests enjoy an indoor pool, a fitness center, and free WiFi in public areas. Self parking is offered for USD 10.00 ...
Hyatt Regency Buffalo / Hotel and Conference Center
Hyatt Regency Buffalo / Hotel and Conference Center
3.5 out of 5.0 Two Fountain Plaza, Buffalo, NY
Free Cancellation
$123
3.9/5 (128 reviews)

Good location. Very friendly helpful staff! Easy to be there.

Reviewed on Jul 20, 2019
At Hyatt Regency Buffalo / Hotel and Conference Center, guests enjoy a full-service spa, an indoor pool, and a 24-hour fitness center. Valet parking is available ...
Hampton Inn Niagara Falls/Blvd
Hampton Inn Niagara Falls/Blvd
2.5 out of 5.0 6501 Niagara Falls Blvd, Niagara Falls, NY
Free Cancellation
$85
4.6/5 (10 reviews)

Easy access to highway and retail. Courteous staff, nice pool & good variety at breakfast--great for a family stay.

Reviewed on Jan 4, 2019
Built in 2014, the brand new Hampton Inn Niagara Falls/Blvd offers an indoor pool, a fitness center, and free WiFi in public areas. There's free parking if you ...

Finding a Hotel in Depew


So you're pondering a getaway to Depew? If you want a place to call home that's located close to Depew attractions, use Orbitz to pick your travel dates, and then presto! Look through the list of hotels and other accommodations to find those that are close to what you want to see while you're in the area.


There are 208 accommodations to pick from within the larger area if you can't find the ideal place to stay in the heart of Depew. Search by filters such as price, neighborhood, guest rating, or popular locations, depending on what's most important to you.


We make it easy to find a convenient flight to Buffalo, NY (BUF-Buffalo Niagara Intl.), which is 2.1 mi (3.3 km) from the city center. Find the perfect flight in a flash by using the filters on our site to narrow down your search.


Accommodations in Depew


There may be a limited number of hotels and accommodations to choose from in Depew, but here some other options located nearby so you've got some choices.

  • 2 hotels in Bowmansville
  • 26 hotels in Cheektowaga
  • 14 hotels in Williamsville

What's the Weather Like in Depew?


If you need to know whether to pack sunglasses or an umbrella for your holiday in Depew, the following weather information may be useful. Depew is typically warmest in July and August, while it’s usually the chilliest in February and January. The rainiest months are November and September, while the driest months are normally February and March. Here's an overview of rain and seasonal temperatures so you're ready for everything Mother Nature can chuck at you:


  • January to March: average temp during the day is 48°F and 18°F at night
  • April to June: average temp during the day is 79°F and 31°F at night
  • July to September: average temp during the day is 80°F and 48°F at night
  • October to December: average temp during the day is 65°F and 20°F at night
  • Annual average rainfall: 40.47 inches

Things to See and Do in Depew


While you're in Depew, you may want to make time to experience the local activities. Explore these well-known attractions during your visit:

  • Walden Galleria Mall
  • KeyBank Center
  • Canalside
  • Buffalo Zoo
  • Shea's Performing Arts Center
  • New Era Field

Recent Reviews

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.