Hotels in Depew

Search over 894 hotels from $82

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Aug 11 - Aug 12
Tonight
Check prices in Depew for tonight, Aug 11 - Aug 12
Aug 12 - Aug 13
Tomorrow night
Check prices in Depew for tomorrow night, Aug 12 - Aug 13

Top Rated Depew Hotels

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Free Cancellation
Reserve now, pay when you stay
2.49 mi from city center
$101 nightly
The price is $118 total per night
$118 total
Aug 16 - Aug 17
Total with taxes and fees
Guests of Buffalo Airport Hotel enjoy a 24-hour gym, free WiFi in public areas, and meeting rooms. There's free parking, as well as a free airport shuttle (available 24 hours). Multilingual staff at the 24-hour front desk can assist with luggage storage, securing valuables, and concierge services. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Free Cancellation
Reserve now, pay when you stay
3.28 mi from city center
$111 nightly
The price is $126 total per night
$126 total
Aug 27 - Aug 28
Total with taxes and fees
Guests staying at Garden Place Hotel enjoy a 24-hour gym, a sauna, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The front desk is staffed 24/7 to help with securing valuables, concierge services, and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a microwave in a common area.
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Free Cancellation
Reserve now, pay when you stay
2.89 mi from city center
$104 nightly
The price is $122 total per night
$122 total
Aug 18 - Aug 19
Total with taxes and fees
Guests of M Hotel Buffalo have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Free Cancellation
Reserve now, pay when you stay
8.61 mi from city center
$152 nightly
The price is $178 total per night
$178 total
Aug 30 - Aug 31
Total with taxes and fees
At Hyatt Regency Buffalo / Hotel and Conference Center, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 29.50 per night. The front desk has multilingual staff on hand 24/7 to help with concierge services, luggage storage, and securing valuables. Additional amenities include meeting rooms, a conference center, and a business center.
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road Grand Island NY
Free Cancellation
17.84 mi from city center
$157 nightly
The price is $179 total per night
$179 total
Sep 10 - Sep 11
Total with taxes and fees
Guests staying at Holiday Inn Express Grand Island - Niagara Falls by IHG enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to assist with concierge services and luggage storage. Additional amenities include meeting rooms, a business center, and a terrace.
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Free Cancellation
2.62 mi from city center
$81 nightly
The price is $95 total per night
$95 total
Sep 8 - Sep 9
Total with taxes and fees
Sleep Inn & Suites Buffalo Airport features a gym, free WiFi in public areas, and a 24-hour business center. You can take advantage of free parking, along with a free airport shuttle (available 24 hours). The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include coffee/tea in a common area, a microwave in a common area, and a meeting room.
Fairbridge Inn Express Buffalo Airport Williamsville

Fairbridge Inn Express Buffalo Airport Williamsville

2 out of 5
7200 Transit Road Buffalo NY
Free Cancellation
Reserve now, pay when you stay
4.4 mi from city center
$72 nightly
The price is $82 total per night
$82 total
Aug 12 - Aug 13
Total with taxes and fees
At Fairbridge Inn Express Buffalo Airport Williamsville, guests have access to free WiFi in public areas, microwave in a common area, and laundry facilities. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include a vending machine, a TV in a common area, and an ATM.
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3 out of 5
145 Innkeepers Lane Buffalo NY
Free Cancellation
Reserve now, pay when you stay
9.2 mi from city center
$97 nightly
The price is $110 total per night
$110 total
Aug 30 - Aug 31
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Buffalo Amherst have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24/7 to help with concierge services, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, laundry facilities, and a convenience store.
Comfort Inn University

Comfort Inn University

2.5 out of 5
1 Flint Rd Buffalo NY
Free Cancellation
7.62 mi from city center
$89 nightly
The price is $102 total per night
$102 total
Aug 30 - Aug 31
Total with taxes and fees
Guests of Comfort Inn University have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and a computer station.
Days Inn & Suites by Wyndham Niagara Falls/Buffalo

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

2.5 out of 5
2821 Niagara Falls Blvd Niagara Falls NY
Free Cancellation
Reserve now, pay when you stay
16.1 mi from city center
$93 nightly
The price is $106 total per night
$106 total
Sep 8 - Sep 9
Total with taxes and fees
Guests of Days Inn & Suites by Wyndham Niagara Falls/Buffalo enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with securing valuables and tours/tickets. Additional amenities include free newspapers, laundry facilities, and a vending machine.
Microtel Inn & Suites by Wyndham Niagara Falls

Microtel Inn & Suites by Wyndham Niagara Falls

2.5 out of 5
7726 Niagara Falls Blvd Niagara Falls NY
Free Cancellation
Reserve now, pay when you stay
18.87 mi from city center
$103 nightly
The price is $117 total per night
$117 total
Sep 8 - Sep 9
Total with taxes and fees
Microtel Inn & Suites by Wyndham Niagara Falls offers a 24-hour gym, conference space, and a 24-hour business center. There's free parking and a free area shuttle. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include coffee/tea in a common area, express check-out, and laundry facilities.
Best Western Buffalo Inn & Suites

Best Western Buffalo Inn & Suites

2.5 out of 5
50 Freeman Rd Buffalo NY
3.51 mi from city center
$131 nightly
The price is $149 total per night
$149 total
Aug 23 - Aug 24
Total with taxes and fees
Best Western Buffalo Inn & Suites features a 24-hour gym, free WiFi in public areas, and coffee in a common area. If you decide to drive, there's free parking. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include a microwave in a common area, laundry facilities, and a TV in a common area.
Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What's the best place for a stay in Depew?

What are some favorite hotels in central Depew?

Here are some of our travelers' favorite hotels in downtown Depew:

Not all of the most important sights are in the heart of Depew, so consider a visit to well-known places in the larger area like Highmark Stadium.

Depew hotels essential information

Accommodation
894 hotels
Lowest Price
$82
Highest Price
$179
Popular hotels
Buffalo Airport Hotel, Garden Place Hotel, M Hotel Buffalo, Hyatt Regency Buffalo / Hotel and Conference Center, Holiday Inn Express Grand Island - Niagara Falls by IHG, Sleep Inn & Suites Buffalo Airport, Fairbridge Inn Express Buffalo Airport Williamsville, La Quinta Inn & Suites by Wyndham Buffalo Amherst, Comfort Inn University, Days Inn & Suites by Wyndham Niagara Falls/Buffalo, Microtel Inn & Suites by Wyndham Niagara Falls, Best Western Buffalo Inn & Suites

Recent Reviews

M Hotel Buffalo

M Hotel Buffalo

4/5 Good
"Breakfast set up was a bottleneck"
A verified traveler stayed at M Hotel Buffalo
Posted 2 hours ago
M Hotel Buffalo

More to Explore