Cheap flights from TRI to SAN (Tri-Cities Regional to San Diego Intl.)

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Cheap Flights from TRI to SAN starting at $295 One Way, $364 Round Trip

Prices starting at $364 for return flights and $295 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Sep 18 - Mon, Sep 21
TRI
Tri-Cities
SAN
San Diego
$364 Roundtrip, just found
$364
Roundtrip
just found
Select Delta flight, departing Fri, Sep 18 from Tri-Cities to San Diego, returning Mon, Sep 21, priced at $364 just found
Fri, Sep 18 - Mon, Sep 21
TRI
Tri-Cities
SAN
San Diego
$364 Roundtrip, just found
$364
Roundtrip
just found
Select American Airlines flight, departing Fri, Sep 18 from Tri-Cities to San Diego, returning Mon, Sep 21, priced at $364 just found
Fri, Sep 11 - Wed, Sep 16
TRI
Tri-Cities
SAN
San Diego
$399 Roundtrip, found 1 day ago
$399
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 11 from Tri-Cities to San Diego, returning Wed, Sep 16, priced at $399 found 1 day ago
Fri, Aug 28 - Wed, Sep 2
TRI
Tri-Cities
SAN
San Diego
$431 Roundtrip, found 1 day ago
$431
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Aug 28 from Tri-Cities to San Diego, returning Wed, Sep 2, priced at $431 found 1 day ago
Fri, Sep 18 - Mon, Sep 21
TRI
Tri-Cities
SAN
San Diego
$435 Roundtrip, just found
$435
Roundtrip
just found
Select American Airlines flight, departing Fri, Sep 18 from Tri-Cities to San Diego, returning Mon, Sep 21, priced at $435 just found

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$188 nightly
The price is $216 total per night from Aug 23 to Aug 24
$216 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 24 to Aug 25
$211 total
Aug 24 - Aug 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,300 reviews)
"Good location, nice staff, clean."

Reviewed on Aug 16, 2026

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$233 nightly
The price is $270 total per night from Aug 30 to Aug 31
$270 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,797 reviews)
"Great experience, very convenient location for all the things"

Reviewed on Aug 16, 2026

Manchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$269 nightly
The price is $309 total per night from Sep 7 to Sep 8
$309 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,817 reviews)
"Great places for a family love everything about this place"

Reviewed on Aug 16, 2026

Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$233 nightly
The price is $270 total per night from Aug 30 to Aug 31
$270 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,797 reviews)
"Great experience, very convenient location for all the things"

Reviewed on Aug 16, 2026

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 24 to Aug 25
$211 total
Aug 24 - Aug 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,300 reviews)
"Good location, nice staff, clean."

Reviewed on Aug 16, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 24 to Aug 25
$211 total
Aug 24 - Aug 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,300 reviews)
"Good location, nice staff, clean."

Reviewed on Aug 16, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$188 nightly
The price is $216 total per night from Aug 23 to Aug 24
$216 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Sep 1 to Sep 2
$156 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,087 reviews)
"Nice stay. Good air conditioning. Musty smell and bouncy bed."

Reviewed on Aug 16, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Sep 7 to Sep 8
$126 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,510 reviews)
"The Pleasant Inn is exactly that...."pleasant". It is an older hotel that has undergone renovations in the bedroom and bathroom. The price and location are fine. Staff are welcoming and organized."

Reviewed on Aug 16, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Aug 17 to Aug 18
$81 total
Aug 17 - Aug 18
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$120 nightly
The price is $137 total per night from Aug 19 to Aug 20
$137 total
Aug 19 - Aug 20
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$239 nightly
The price is $275 total per night from Sep 14 to Sep 15
$275 total
Sep 14 - Sep 15
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
8.6/10 Excellent! (2,338 reviews)
"Nice private beach on the bay. Short walk to the ocean beach and Belmont park."

Reviewed on Aug 16, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$214 nightly
The price is $246 total per night from Aug 30 to Aug 31
$246 total
Aug 30 - Aug 31
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,432 reviews)
"Our room was ok clean. The bed was really hard and there was a gap underneath the door. The housekeeping was washing the walkway and when we entered the room the carpet was soaking wet. The tall tropical plants look unkept. We did enjoy the pool areas. It was an overall ok stay . The surrounding ..."

Reviewed on Aug 15, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$315 nightly
The price is $362 total per night from Sep 8 to Sep 9
$362 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TRI to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TRI Address & GPS
Address:
2525 Tennessee 75
Bristol, VA/Johnson City/Kingsport TN, 37617
United States
IATA Code:
TRI
Longitude:
-82.407852
Latitude:
36.481109
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

What is the shortest flight from TRI to San Diego Intl. Airport (SAN)?
Use the opportunity to unwind on the flight from Blountville to San Diego. The shortest flight time from Tri-Cities Airport to SAN is 6 hours and 20 minutes, which gives you loads of time to indulge in a tipple or get engrossed in a book.
How many hours flight from TRI to SAN?
From Tri-Cities Airport to SAN, you'll be in your seat for roughly 6 hours and 26 minutes. Settle back, order a glass of bubbly and take out your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Tri-Cities Airport to San Diego Intl. Airport (SAN)?
If you're hoping to book with an airline that flies direct from TRI to San Diego Intl. Airport (SAN), you won't have much luck. You'll have to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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