Cheap flights from MOB to SAN (Mobile Regional to San Diego Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MOB to SAN starting at $386 One Way, $350 Round Trip

Prices starting at $350 for return flights and $386 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, May 13 - Wed, May 26
MOB
Mobile
SAN
San Diego
$350 Roundtrip, found 16 hours ago
$350
Roundtrip
found 16 hours ago
Select Delta flight, departing Thu, May 13 from Mobile to San Diego, returning Wed, May 26, priced at $350 found 16 hours ago
Fri, Sep 25 - Tue, Sep 29
MOB
Mobile
SAN
San Diego
$355 Roundtrip, found 5 days ago
$355
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 25 from Mobile to San Diego, returning Tue, Sep 29, priced at $355 found 5 days ago
Thu, May 13 - Wed, May 26
MOB
Mobile
SAN
San Diego
$379 Roundtrip, found 16 hours ago
$379
Roundtrip
found 16 hours ago
Select Delta flight, departing Thu, May 13 from Mobile to San Diego, returning Wed, May 26, priced at $379 found 16 hours ago
Fri, Sep 25 - Tue, Sep 29
MOB
Mobile
SAN
San Diego
$384 Roundtrip, found 5 days ago
$384
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Sep 25 from Mobile to San Diego, returning Tue, Sep 29, priced at $384 found 5 days ago
Fri, Sep 25 - Tue, Sep 29
MOB
Mobile
SAN
San Diego
$408 Roundtrip, found 5 days ago
$408
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Sep 25 from Mobile to San Diego, returning Tue, Sep 29, priced at $408 found 5 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$188 nightly
The price is $216 total per night from Sep 3 to Sep 4
$216 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 3 to Sep 4
$211 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,311 reviews)
"Excellent location with a great view of the bay in tower 3."

Reviewed on Aug 30, 2026

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$246 nightly
The price is $285 total per night from Sep 7 to Sep 8
$285 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
Manchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$246 nightly
The price is $285 total per night from Sep 7 to Sep 8
$285 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
Manchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$254 nightly
The price is $292 total per night from Sep 7 to Sep 8
$292 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 3 to Sep 4
$211 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,311 reviews)
"Excellent location with a great view of the bay in tower 3."

Reviewed on Aug 30, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 3 to Sep 4
$211 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,311 reviews)
"Excellent location with a great view of the bay in tower 3."

Reviewed on Aug 30, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$188 nightly
The price is $216 total per night from Sep 3 to Sep 4
$216 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$148 nightly
The price is $170 total per night from Sep 27 to Sep 28
$170 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,088 reviews)
"So convenient, close to MCRD. Very helpful with maps and restaurants. Very friendly!"

Reviewed on Aug 29, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$109 nightly
The price is $125 total per night from Aug 31 to Sep 1
$125 total
Aug 31 - Sep 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Aug 31 to Sep 1
$81 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,188 reviews)
"Manager was rude and unprofessional. I don’t know how he has a job"

Reviewed on Aug 30, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$108 nightly
The price is $124 total per night from Sep 30 to Oct 1
$124 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,724 reviews)
"Yes it was very clean and outstanding guest services. Sandy is awesome, friendly and represents the Kings Inn professionally and positively. As a happy guest we have been staying here for 16 year's"

Reviewed on Aug 29, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from Sep 30 to Oct 1
$257 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
8.6/10 Excellent! (2,371 reviews)
"I arrived early to check in possibly at 3 PM. I did not get my room until 5 PM. There was no sense of urgency when I called to get my room serviced with towels and coffee. After my third day, I asked to have the sheets changed and it took four phone calls three to housekeeping and one to the front ..."

Reviewed on Aug 30, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$186 nightly
The price is $213 total per night from Aug 31 to Sep 1
$213 total
Aug 31 - Sep 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,439 reviews)
"1"

Reviewed on Aug 30, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$294 nightly
The price is $339 total per night from Sep 7 to Sep 8
$339 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MOB to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MOB Address & GPS
Address:
8400 Airport Blvd.
Mobile AL, 36608-0004
United States
IATA Code:
MOB
Longitude:
-88.244753
Latitude:
30.681085
Time Zone:
America/Chicago
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Mobile Regional Airport (MOB) to SAN?
Unfortunately, direct flights aren't an option when it comes to flying from MOB to San Diego Airport. However, there are a range of companies that service this route with just one stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from Mobile Regional Airport (MOB) to SAN?
From Mobile, the wonderful sights and sounds of San Diego are around 6 hours and 25 minutes away. Lock in your favorite seat, or maybe even one with a bit more legroom, and fly to your destination in pure comfort.
How many hours flight from Mobile Regional Airport to San Diego Intl. Airport (SAN)?
It usually takes around 6 hours and 30 minutes to jet from MOB to SAN. Get through the flight by watching some films or listening to audiobooks. Alternatively, catch up on some Zs.
What airlines have the most flights from Mobile Regional Airport to San Diego Intl. Airport (SAN)?
You won't be able to find any airlines that operate direct flights between Mobile Regional Airport and SAN. Be organized and secure a multi or single-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore