Cheap flights from MLI to SAN (Quad City Intl. to San Diego Intl.)

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Cheap Flights from MLI to SAN starting at $128 One Way, $253 Round Trip

Prices starting at $253 for return flights and $128 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, May 5 - Sat, May 9
MLI
Moline
SAN
San Diego
$253 Roundtrip, found 4 days ago
$253
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 5 from Moline to San Diego, returning Sat, May 9, priced at $253 found 4 days ago
Tue, May 5 - Sat, May 9
MLI
Moline
SAN
San Diego
$253 Roundtrip, found 4 days ago
$253
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 5 from Moline to San Diego, returning Sat, May 9, priced at $253 found 4 days ago
Tue, May 5 - Sat, May 9
MLI
Moline
SAN
San Diego
$258 Roundtrip, found 4 days ago
$258
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 5 from Moline to San Diego, returning Sat, May 9, priced at $258 found 4 days ago
Tue, May 5 - Sat, May 9
MLI
Moline
SAN
San Diego
$263 Roundtrip, found 4 days ago
$263
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 5 from Moline to San Diego, returning Sat, May 9, priced at $263 found 4 days ago
Tue, May 5 - Sat, May 9
MLI
Moline
SAN
San Diego
$266 Roundtrip, found 4 days ago
$266
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 5 from Moline to San Diego, returning Sat, May 9, priced at $266 found 4 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$235 nightly
The price is $270 total per night from Mar 20 to Mar 21
$270 total
Mar 20 - Mar 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,338 reviews)
Roll in showers need the soap and shampoo moved closer to the bench.

Reviewed on Feb 23, 2026

Sheraton San Diego Resort
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$149 nightly
The price is $171 total per night from Feb 24 to Feb 25
$171 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,419 reviews)
We stayed for two nights, a family of 8 with three rooms. The rooms were very spacious and the balconies are definitely a plus. Our only frustration was coin laundry facilities with no way to get change. As a family on a little road trip, laundry was a necessity but overall a nice stay.

Reviewed on Feb 22, 2026

Bay Club Hotel & Marina
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
$146 nightly
The price is $168 total per night from Mar 1 to Mar 2
$168 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
9.2/10 Wonderful! (663 reviews)
Good.

Reviewed on Feb 22, 2026

Hampton Inn & Suites by Hilton San Diego SeaWorld
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$231 nightly
The price is $266 total per night from Mar 1 to Mar 2
$266 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,436 reviews)
Room was not ready at time of check in 4pm had to wait 1 hour checked in at 5pm overall room was clean view was good

Reviewed on Feb 23, 2026

Paradise Point Resort & Spa
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$149 nightly
The price is $171 total per night from Feb 24 to Feb 25
$171 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,419 reviews)
We stayed for two nights, a family of 8 with three rooms. The rooms were very spacious and the balconies are definitely a plus. Our only frustration was coin laundry facilities with no way to get change. As a family on a little road trip, laundry was a necessity but overall a nice stay.

Reviewed on Feb 22, 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$254 nightly
The price is $294 total per night from Feb 27 to Feb 28
$294 total
Feb 27 - Feb 28
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,343 reviews)
El Cuarto necesitaba mas limpieza y no es la gran cosa el hotel

Reviewed on Feb 23, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$185 nightly
The price is $214 total per night from Mar 1 to Mar 2
$214 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,057 reviews)
Hotel was dated. Hot water took at least 10 minutes from the time you turned on the faucet. The constant sales pitches. It did have a good location but will not stay there again.

Reviewed on Feb 23, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$235 nightly
The price is $270 total per night from Mar 20 to Mar 21
$270 total
Mar 20 - Mar 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,338 reviews)
Roll in showers need the soap and shampoo moved closer to the bench.

Reviewed on Feb 23, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Mar 1 to Mar 2
$156 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,064 reviews)
Nice clean room with everything you need. The breakfast was perfect and quick.

Reviewed on Feb 22, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$94 nightly
The price is $107 total per night from Feb 24 to Feb 25
$107 total
Feb 24 - Feb 25
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.4/10 Very Good! (1,328 reviews)
Very friendly staff. Clean rooms. Fairly quiet. Lots of restaurants nearby

Reviewed on Feb 23, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$64 nightly
The price is $73 total per night from Feb 24 to Feb 25
$73 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,110 reviews)
Staff was sweet the lady was in the front by herself and had a big line so the wait was long but we were helped quickly. The room was nice had a funny smell but overall pretty clean

Reviewed on Feb 21, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$97 nightly
The price is $112 total per night from Mar 2 to Mar 3
$112 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,634 reviews)
Rooms were clean and always neat when you got back to the room

Reviewed on Feb 22, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$209 nightly
The price is $240 total per night from Mar 1 to Mar 2
$240 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (1,891 reviews)
Staff was excellent! Breakfast at Dockside as well as drinks at Bianchi were awesome. Greet location as well! The room however was very outdated and smelled a bit musty.

Reviewed on Feb 22, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$189 nightly
The price is $217 total per night from Mar 2 to Mar 3
$217 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,118 reviews)
Great location, very clean. Walking trails everywhere.

Reviewed on Feb 23, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$258 nightly
The price is $297 total per night from Mar 8 to Mar 9
$297 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,168 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
Great location for beach proximity and served us well for a short vacation. We went in February and many amenities such as kids activities were lacking which made it feel like less of a resort experience. But overall kids had a great time in pool, hot tub and arcade.

Reviewed on Feb 23, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MLI to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MLI Address & GPS
Address:
2200 69th Ave.
Moline IL, 61265
United States
IATA Code:
MLI
Longitude:
-90.506111
Latitude:
41.453897
Time Zone:
America/Chicago
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Quad City Intl. Airport to SAN?
While you can't fly straight from Quad City Intl. Airport (MLI) to San Diego Airport, there are plenty of carriers that operate on this route with just one stop. Why not check if the dates and times available with American Airlines or United Airlines match your travel plans? If they don't, you could always check out Delta Air Lines.
What is the shortest flight from MLI to SAN?
Flying from Quad City Intl. Airport to SAN will take a minimum of 6 hours and 5 minutes. Enjoy a tipple and get stuck into that book — now's your chance to take some time out.
How many hours flight from MLI to San Diego Intl. Airport (SAN)?
Get comfy, because the average journey from Quad City Intl. Airport to SAN is 6 hours and 12 minutes. Enjoy some wine with your meal, finally finish that book ... You'll have ample time to sit back and enjoy the ride.
What airlines have the most flights from Quad City Intl. Airport to San Diego Airport?
Do a bit of shopping, tuck into some takeaway, chat with a stranger ... Airport stopovers don't have to be a drag! If you're heading from Quad City Intl. Airport to San Diego Intl. Airport (SAN), you can't fly direct. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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